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(R)-(+)-α-Hydroxy-γ-butyrolactone - 98%, high purity , CAS No.56881-90-4
Discover (R)-(+)-α-Hydroxy-γ-butyrolactone by Aladdin Scientific in 98% for only $148.90. Available - in Ligands at Aladdin Scientific. Tags: asymmetric synthesis, Chiral heterocyclic block.
Basic Description Synonyms (R)-dihydro-3-hydroxyfuran-2(3H)-one | AS-61367 | (3R)-3-hydroxyoxolan-2-one | AKOS015909640 | SCHEMBL183974 | SG03T0K3QH | 2-HYDROXY-.GAMMA.-BUTYROLACTONE, (+)- | IDI1_015695 | T72635 | UNII-SG03T0K3QH | EN300-2009870 | Q27289197 | 2-HYDROXY-.GAMMA.-BUTY Specifications & Purity ≥98% Storage Temp Store at 2-8°C,Argon charged Shipped In Wet ice Product Description Application：
(R)-(+)-α-Hydroxy-γ-butyrolactone can be used as a starting material to synthesize:
δ-Azaproline by reacting with benzyloxycarbonyl aminophthalimide via Mitsunobu reactions；
Homochiral (R)-2,4-dihydroxybutyramide seco-pseudonucleoside reagents；
Botryolide B via esterification and ring-closing metathesis reaction；
Pregnane derivatives containing γ-butyrolactones as potential glucocorticoid agonists；
Names and Identifiers IUPAC Name (3R)-3-hydroxyoxolan-2-one INCHI InChI=1S/C4H6O3/c5-3-1-2-7-4(3)6/h3,5H,1-2H2/t3-/m1/s1 InChi Key FWIBCWKHNZBDLS-GSVOUGTGSA-N Canonical SMILES C1COC(=O)C1O Isomeric SMILES C1COC(=O)[C@@H]1O WGK Germany 3 PubChem CID 7157070 Molecular Weight 102.09 Beilstein 80588 Reaxy-Rn 80588
Chemical and Physical Properties Sensitivity Moisture Sensitive Refractive Index 1.47 Specific Rotation[α] 71.5° (C=1,CHCl3) Flash Point(°F) >235.4 °F Flash Point(°C) >113 °C Boil Point(°C) 133°C/10mmHg(lit.)
Safety and Hazards(GHS) WGK Germany 3 Reaxy-Rn 80588
References 1. Natalia N Dioubankova,Andrey D Malakhov,Dmitry A Stetsenko,Vladimir A Korshun,Michael J Gait. (2002-12-20) (R)-2,4-Dihydroxybutyramide seco-pseudonucleosides: new versatile homochiral synthons for synthesis of modified oligonucleotides.. Organic letters, 4 ((26)): (4607-4610). [PMID:12489941 ] 2. Xiaohui Gou,Yifan Xue,Huiwen Zheng,Guobin Yang,Shuo Chen,Zhi Chen,Guohua Yuan. (2020-07-17) Gelatinases Cleave Dentin Sialoprotein Intracellularly.. Frontiers in physiology, 11 (686-686). [PMID:32670089 ]
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