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R-(−)-Apomorphine hydrochloride hemihydrate - 98%, high purity , CAS No.41372-20-7
Dopamine pan-receptor agonist
Basic Description Synonyms Kw-6500 | NCIOpen2_005869 | W-107235 | Apomorphine SL | KYNMOBI | NSC-755875 | (-)-Apomorphinium hydrochloride | APOMORPHINE HYDROCHLORIDE [EMA EPAR] | Apomorphine hydrochloride [USP] | Apomorphinum hydrochloricum | AT18583 | N-(4-((4-(Dimethylamino)pheny Specifications & Purity ≥98% Biochemical and Physiological Mechanisms 'Biological description': "Dopamine pan-receptor agonist. Displays anti-Parkinson's activity in vivo . Protects against MPTP-induced neurotoxicity (mouse model).", 'General notes': 'Solutions in distilled water may be stored at -20°C for up to 1 week. Storage Temp Store at -20°C,Argon charged,Desiccated Shipped In Ice chest + Ice pads Note Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one week. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Toxic, refer to SDS for further information . Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
Mechanisms of Action Mechanism of Action Action Type target ID Target Name Target Type Target Organism Binding Site Name References
Names and Identifiers IUPAC Name (6aR)-6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol;hydrate;dihydrochloride INCHI InChI=1S/2C17H17NO2.2ClH.H2O/c2*1-18-8-7-10-3-2-4-12-15(10)13(18)9-11-5-6-14(19)17(20)16(11)12;;;/h2*2-6,13,19-20H,7-9H2,1H3;2*1H;1H2/t2*13-;;;/m11.../s1 InChi Key CXWQXGNFZLHLHQ-DPFCLETOSA-N Canonical SMILES CN1CCC2=C3C1CC4=C(C3=CC=C2)C(=C(C=C4)O)O.CN1CCC2=C3C1CC4=C(C3=CC=C2)C(=C(C=C4)O)O.O.Cl.Cl Isomeric SMILES CN1CCC2=C3[C@H]1CC4=C(C3=CC=C2)C(=C(C=C4)O)O.CN1CCC2=C3[C@H]1CC4=C(C3=CC=C2)C(=C(C=C4)O)O.O.Cl.Cl PubChem CID 107882 Molecular Weight 312.79
Chemical and Physical Properties Solubility Soluble in water to 50 mM Sensitivity Hygroscopic ight sensitive；heat sensitive Melt Point(°C) 285-287 °C (lit.)
Safety and Hazards(GHS) Pictogram(s) GHS06 , GHS08 , GHS07 Signal Danger Hazard Statements H301: Toxic if swallowed
H302: Harmful if swallowed
H317: May cause an allergic skin reaction
H334: May cause allergy or asthma symptoms or breathing difficulties if inhaled
H312: Harmful in contact with skin
H332: Harmful if inhaled
Precautionary Statements P261: Avoid breathing dust/fume/gas/mist/vapors/spray.
P280: Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352: IF ON SKIN: wash with plenty of water.
P321: Specific treatment (see ... on this label).
P405: Store locked up.
P501: Dispose of contents/container to ...
P264: Wash hands [and …] thoroughly after handling.
P284: [In case of inadequate ventilation] Wear respiratory protection.
P271: Use only outdoors or in a well-ventilated area.
P270: Do not eat, drink or smoke when using this product.
P304+P340: IF INHALED: Remove person to fresh air and keep comfortable for breathing.
P272: Contaminated work clothing should not be allowed out of the workplace.
P333+P313: IF SKIN irritation or rash occurs: Get medical advice/attention.
P362+P364: Take off contaminated clothing and wash it before reuse.
P330: Rinse mouth.
P301+P316: IF SWALLOWED: Get emergency medical help immediately.
P301+P317: IF SWALLOWED: Get medical help.
P317: Get emergency medical help.
P342+P316: If experiencing respiratory symptoms: Get emergence medical help immediately.
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