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(R)-GSK-3685032 - 98%, high purity , CAS No.2170140-50-6

Item Number

G648996

Grouped product items
SKU	Size	Availability	Price	Qty
G648996-5mg	5mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$500.90
G648996-10mg	10mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$850.90

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Basic Description

Specifications & Purity	98%
Storage Temp	Store at 2-8°C,Protected from light,Desiccated
Shipped In	Wet ice
Product Description	(R)-GSK-3685032 is the R-enantiomer of GSK-3685032. GSK-3685032 is a non-time-dependent, noncovalently, first-in-class reversible DNMT1 -selective inhibitor, with an IC 50 of 0.036 μM. GSK-3685032 induces robust loss of DNA methylation, transcriptional activation, and cancer cell growth inhibition Form:Solid IC50& Target:DNMT1

Canonical SMILES	N#CC1=C(N2CCC(CC2)N)N=C(C(C#N)=C1CC)S[C@H](C3=CC=CC=C3)C(N)=O
Molecular Weight	420.53

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Solubility	DMSO : 60 mg/mL (142.68 mM; Need ultrasonic)

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