| SKU | Size | Availability | Price | Qty |
|---|---|---|---|---|
| R348368-5mg | 5mg | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $285.90 |
a venlafaxine metabolite
| Synonyms | E98735 | (-)-O-Desmethylvenlafaxine | (R)-4-(2-(dimethylamino)-1-(1-hydroxycyclohexyl)ethyl)phenol | AKOS015911238 | O-Desmethylvenlafaxine, (-)- | DTXSID10162168 | SCHEMBL3277527 | HY5T9WKI4O | R-(-)-O-Desmethyl Venlafaxine | 29J | 4-[(1r)-2-(Dimethylami |
|---|---|
| Storage Temp | Store at -20°C |
| Shipped In | Ice chest + Ice pads |
| Product Description | R-(-)-O-Desmethyl Venlafaxine is a metabolite of R-Venlafaxine , a selective serotonin noradrenaline reuptake inhibitor. This bicyclic molecule facilitates neurotransmission by preventing presynaptic reuptake, resulting in a higher concentration of neurotransmitters located within the synapse. It is known that the neurotransmitters most effected by this inhibitor are norepinephrine and serotonin, which weakly suppress dopamine at high concentrations. Furthermore, studies show that R-(-)-O-Desmethyl Venlafaxine can be seperated from Venlafaxine using LC-MS/MS in rat plasma. |
| IUPAC Name | 4-[(1R)-2-(dimethylamino)-1-(1-hydroxycyclohexyl)ethyl]phenol |
|---|---|
| INCHI | InChI=1S/C16H25NO2/c1-17(2)12-15(13-6-8-14(18)9-7-13)16(19)10-4-3-5-11-16/h6-9,15,18-19H,3-5,10-12H2,1-2H3/t15-/m0/s1 |
| InChi Key | KYYIDSXMWOZKMP-HNNXBMFYSA-N |
| Canonical SMILES | CN(C)CC(C1=CC=C(C=C1)O)C2(CCCCC2)O |
| Isomeric SMILES | CN(C)C[C@@H](C1=CC=C(C=C1)O)C2(CCCCC2)O |
| PubChem CID | 12018336 |
| Molecular Weight | 263.38 |
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| Solubility | Soluble in ethanol, and methanol. |
|---|---|
| Refractive Index | n20D1.57 (Predicted) |
| Boil Point(°C) | 403.79° C at 760 mmHg (Predicted) |
| Melt Point(°C) | 208-213° C |
