Grouped product items

SKU

Size

Availability

Price

Qty

P106007-1g

Available within 8-12 weeks(?)

$16.90

P106007-5g

In stock

$53.90

P106007-10g

10g

In stock

$93.90

P106007-25g

25g

In stock

$156.90

P106007-50g

50g

In stock

$238.90

P106007-100g

100g

In stock

$380.90

Basic Description

Synonyms	Phenylephrine HCl \| PHENYLEPHRINE HYDROCHLORIDE (EP MONOGRAPH) \| Benzyl alcohol, m-hydroxy-alpha-((methylamino)methyl)-, hydrochloride, (-)- \| PHENYLEPHRINE HYDROCHLORIDE [USP MONOGRAPH] \| Phenylephrine hydrochloride [USP:JAN] \| D-(-)-Phenylephrine hydroc
Specifications & Purity	≥99%
Biochemical and Physiological Mechanisms	α1-adrenoceptor agonist.α 1 Adrenoceptor agonist. pK i values are 4.87, 4.70 and 5.86 for adrenoceptor subtypes α 1B , α 1C and α 1A/D , respectively. Vasoconstrictor. Active in vivo , may cross the blood-brain barrier.
Storage Temp	Store at 2-8°C,Argon charged
Shipped In	Wet ice
Action Type	AGONIST
Mechanism of action	Adrenergic receptor alpha-1 agonist
Note	Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

Associated Targets

EHMT2 Tchem Histone-lysine N-methyltransferase EHMT2 0 Activities

Discover Target: EHMT2

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

CBX1 Tbio Chromobox protein homolog 1 0 Activities

Discover Target: CBX1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

GMNN Tbio Geminin 0 Activities

Discover Target: GMNN

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

HIF1A Tchem Hypoxia-inducible factor 1-alpha 0 Activities

Discover Target: HIF1A

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

GALC Tbio Galactocerebrosidase 0 Activities

Discover Target: GALC

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

TXNRD1 Tclin Thioredoxin reductase 1, cytoplasmic 0 Activities

Discover Target: TXNRD1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

SLCO1B1 Tchem Solute carrier organic anion transporter family member 1B1 0 Activities

Discover Target: SLCO1B1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

SLCO1B3 Tchem Solute carrier organic anion transporter family member 1B3 0 Activities

Discover Target: SLCO1B3

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

PMP22 Tbio Peripheral myelin protein 22 0 Activities

Discover Target: PMP22

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

LMNA Tbio Prelamin-A/C 0 Activities

Discover Target: LMNA

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

GAA Tclin Lysosomal alpha-glucosidase 0 Activities

Discover Target: GAA

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

BLM Tchem Bloom syndrome protein 0 Activities

Discover Target: BLM

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

TDP1 Tchem Tyrosyl-DNA phosphodiesterase 1 0 Activities

Discover Target: TDP1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

ADRB2 Tclin Beta-2 adrenergic receptor 0 Activities

Discover Target: ADRB2

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

HTR2A Tclin 5-hydroxytryptamine receptor 2A 0 Activities

Discover Target: HTR2A

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

GLP1R Tclin Glucagon-like peptide 1 receptor 0 Activities

Discover Target: GLP1R

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

IDH1 Tclin Isocitrate dehydrogenase [NADP] cytoplasmic 0 Activities

Discover Target: IDH1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

TP53 Tchem Cellular tumor antigen p53 0 Activities

Discover Target: TP53

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

OPRM1 Tclin Mu-type opioid receptor 0 Activities

Discover Target: OPRM1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

KDM4E Tchem Lysine-specific demethylase 4E 0 Activities

Discover Target: KDM4E

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

Names and Identifiers

IUPAC Name	3-[(1R)-1-hydroxy-2-(methylamino)ethyl]phenol;hydrochloride
INCHI	InChI=1S/C9H13NO2.ClH/c1-10-6-9(12)7-3-2-4-8(11)5-7;/h2-5,9-12H,6H2,1H3;1H/t9-;/m0./s1
InChi Key	OCYSGIYOVXAGKQ-FVGYRXGTSA-N
Canonical SMILES	CNCC(C1=CC(=CC=C1)O)O.Cl
Isomeric SMILES	CNC[C@@H](C1=CC(=CC=C1)O)O.Cl
WGK Germany	3
RTECS	DO7525000
PubChem CID	5284443
Molecular Weight	203.67
Beilstein	4158948
Reaxy-Rn	4158948

Certificates

Certificate of Analysis(COA)

Enter Lot Number to search for COA:

To view the certificate results,please click on a Lot number.For Lot numbers from past orders,please use our order status section

13 results found

Lot Number	Certificate Type	Date	Item
E2406453	Certificate of Analysis	Mar 26, 2024	P106007
E2406454	Certificate of Analysis	Mar 26, 2024	P106007
D2402410	Certificate of Analysis	Mar 14, 2024	P106007
D2402411	Certificate of Analysis	Mar 14, 2024	P106007
D2402412	Certificate of Analysis	Mar 14, 2024	P106007
D2402413	Certificate of Analysis	Mar 14, 2024	P106007
J2218246	Certificate of Analysis	Aug 03, 2022	P106007
J2218250	Certificate of Analysis	Aug 03, 2022	P106007
J2218275	Certificate of Analysis	Aug 03, 2022	P106007
J2218285	Certificate of Analysis	Aug 03, 2022	P106007
J2218286	Certificate of Analysis	Aug 03, 2022	P106007
J2218287	Certificate of Analysis	Aug 03, 2022	P106007
L2318076	Certificate of Analysis	Aug 27, 2021	P106007

Chemical and Physical Properties

Sensitivity	Moisture sensitive.
Specific Rotation[α]	-45.5 ° (C=1, H2O)
Melt Point(°C)	143°C

Safety and Hazards(GHS)

Pictogram(s)	GHS08, GHS07
Signal	Warning
Hazard Statements	H315:Causes skin irritation H319:Causes serious eye irritation H335:May cause respiratory irritation H302:Harmful if swallowed H317:May cause an allergic skin reaction H312:Harmful in contact with skin H361:Suspected of damaging fertility or the unborn child
Precautionary Statements	P261:Avoid breathing dust/fume/gas/mist/vapors/spray. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of water. P321:Specific treatment (see ... on this label). P405:Store locked up. P501:Dispose of contents/container to ... P264:Wash hands [and …] thoroughly after handling. P271:Use only outdoors or in a well-ventilated area. P270:Do not eat, drink or smoke when using this product. P304+P340:IF INHALED: Remove person to fresh air and keep comfortable for breathing. P403+P233:Store in a well-ventilated place. Keep container tightly closed. P272:Contaminated work clothing should not be allowed out of the workplace. P333+P313:IF SKIN irritation or rash occurs: Get medical advice/attention. P362+P364:Take off contaminated clothing and wash it before reuse. P330:Rinse mouth. P203:Obtain, read and follow all safety instructions before use. P264+P265:Wash hands [and …] thoroughly after handling. Do not touch eyes. P301+P317:IF SWALLOWED: Get medical help. P318:if exposed or concerned, get medical advice. P317:Get emergency medical help. P337+P317:If eye irritation persists: Get medical help. P332+P317:If skin irritation occurs: Get medical help. P319:Get medical help if you feel unwell.
WGK Germany	3
RTECS	DO7525000
Reaxy-Rn	4158948
Merck Index	7286

Alternative Products

FAQs and Articles

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The Importance of L-Tyrosine in Laboratory Research and Cell Culture

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cell culture Amino acids Solvents Peptides Cell biology Metabolites Laboratory chemicals Medium component Liquid media

References

1. Tyurin-Kuzmin PA et al.. (2016) Activation of ß-adrenergic receptors is required for elevated a1A-adrenoreceptors expression and signaling in mesenchymal stromal cells.. Sci Rep, 6 (32835). [PMID:27596381]
2. Tyurin-Kuzmin PA et al.. (2018) Noradrenaline Sensitivity Is Severely Impaired in Immortalized Adipose-Derived Mesenchymal Stem Cell Line.. Int J Mol Sci, 19 (12): [PMID:30469522]
3. Lippiello P et al.. (2015) Noradrenergic modulation of the parallel fiber-Purkinje cell synapse in mouse cerebellum.. Neuropharmacology, 89 (33-42). [PMID:25218865]
4. Jiang DS et al.. (2016) The potential role of lysosome-associated membrane protein 3 (LAMP3) on cardiac remodelling.. Am J Transl Res, 8 (37-48). [PMID:27069538]

Solution Calculators

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(R)-(-)-Phenylephrine hydrochloride - 99%, high purity , Adrenergic receptor alpha-1 agonist, CAS No.61-76-7, Adrenergic receptor alpha-1 agonist

Basic Description

Associated Targets

EHMT2 Tchem Histone-lysine N-methyltransferase EHMT2 0 Activities

CBX1 Tbio Chromobox protein homolog 1 0 Activities

GMNN Tbio Geminin 0 Activities

HIF1A Tchem Hypoxia-inducible factor 1-alpha 0 Activities

GALC Tbio Galactocerebrosidase 0 Activities

TXNRD1 Tclin Thioredoxin reductase 1, cytoplasmic 0 Activities

SLCO1B1 Tchem Solute carrier organic anion transporter family member 1B1 0 Activities

SLCO1B3 Tchem Solute carrier organic anion transporter family member 1B3 0 Activities

PMP22 Tbio Peripheral myelin protein 22 0 Activities

LMNA Tbio Prelamin-A/C 0 Activities

GAA Tclin Lysosomal alpha-glucosidase 0 Activities

BLM Tchem Bloom syndrome protein 0 Activities

TDP1 Tchem Tyrosyl-DNA phosphodiesterase 1 0 Activities

ADRB2 Tclin Beta-2 adrenergic receptor 0 Activities

HTR2A Tclin 5-hydroxytryptamine receptor 2A 0 Activities

GLP1R Tclin Glucagon-like peptide 1 receptor 0 Activities

IDH1 Tclin Isocitrate dehydrogenase [NADP] cytoplasmic 0 Activities

TP53 Tchem Cellular tumor antigen p53 0 Activities

OPRM1 Tclin Mu-type opioid receptor 0 Activities

KDM4E Tchem Lysine-specific demethylase 4E 0 Activities

Names and Identifiers

Certificates

Certificate of Analysis(COA)

more

Chemical and Physical Properties

Safety and Hazards(GHS)

Related Documents

Alternative Products

FAQs and Articles

References

Solution Calculators

Molarity Calculator

Dilution Calculator

Reconstitution Calculator

SKU	Size	Availability	Price
P106007-1g	1g	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$16.90
P106007-5g	5g	In stock	$53.90
P106007-10g	10g	In stock	$93.90
P106007-25g	25g	In stock	$156.90
P106007-50g	50g	In stock	$238.90
P106007-100g	100g	In stock	$380.90