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(R)-phosphoric acid mono-[2-amino-2-(3-octyl-phenylcarbamoyl)-ethyl] ester - >99%, high purity , CAS No.449173-19-7, Antagonist of S1P 1 receptor;Antagonist of S1P 3 receptor

  • Moligand™
  • ≥99%
Item Number
R130529
Grouped product items
SKUSizeAvailabilityPrice Qty
R130529-1mg
1mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$68.90
R130529-5mg
5mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$206.90
R130529-10mg
10mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$325.90

S1P1and S1P3antagonist

Basic Description

SynonymsVPC 230192-Amino-N-(3-octylphenyl)-3-(phosphonooxy)-propanamaide
Specifications & PurityMoligand™, ≥99%
Biochemical and Physiological MechanismsSphingosine-1-phosphate receptor antagonist; inhibits S1P1and S1P3receptors (pKivalues are 7.86 and 5.93 respectively).
Shipped InNormal
GradeMoligand™
Action TypeANTAGONIST
Mechanism of actionAntagonist of S1P 1 receptor;Antagonist of S1P 3 receptor

Associated Targets

S1PR5 Tclin Sphingosine 1-phosphate receptor 5 1 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

S1PR2 Tchem Sphingosine 1-phosphate receptor 2 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

S1PR4 Tclin Sphingosine 1-phosphate receptor 4 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

S1PR1 Tclin Sphingosine 1-phosphate receptor 1 2 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

S1PR3 Tclin Sphingosine 1-phosphate receptor 3 1 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

Names and Identifiers

IUPAC Name [(2R)-2-amino-3-(3-octylanilino)-3-oxopropyl] dihydrogen phosphate
INCHI InChI=1S/C17H29N2O5P/c1-2-3-4-5-6-7-9-14-10-8-11-15(12-14)19-17(20)16(18)13-24-25(21,22)23/h8,10-12,16H,2-7,9,13,18H2,1H3,(H,19,20)(H2,21,22,23)/t16-/m1/s1
InChi Key MRUSUGVVWGNKFE-MRXNPFEDSA-N
Canonical SMILES CCCCCCCCC1=CC(=CC=C1)NC(=O)C(COP(=O)(O)O)N
Isomeric SMILES CCCCCCCCC1=CC(=CC=C1)NC(=O)[C@@H](COP(=O)(O)O)N
PubChem CID 11588811
Molecular Weight 372.396

Certificates

Certificate of Analysis(COA)

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Chemical and Physical Properties

SolubilitySolvent:Acidified DMSO (5% 1N HCl in DMSO) , Max Conc. mg/mL: 3.72, Max Conc. mM: 10 with gentle warming; Solvent:2eq. NaOH, Max Conc. mg/mL: 18.62, Max Conc. mM: 50

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Solution Calculators