R-Venlafaxine-di-p-toluoyl-D-tartrate Salt , CAS No.272788-00-8

Item Number
R357440
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R357440-5mg
5mg
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$581.90

Discover R-Venlafaxine-di-p-toluoyl-D-tartrate Salt by Aladdin Scientific in for only $581.90. Available - in Ligands at Aladdin Scientific. a (?)-Venlafaxine derivative Tags: .

Basic Description

SynonymsSCHEMBL4310168 | (2S,3S)-2,3-bis[(4-methylbenzoyl)oxy]butanedioic acid;1-[(1R)-2-(dimethylamino)-1-(4-methoxyphenyl)ethyl]cyclohexan-1-ol | R-Venlafaxine Di-p-toluoyl-D-tartrate Salt | J-016718 | DTXSID60476505 | R-Venlafaxine-di-p-toluoyl-D-tartrate Salt
Storage TempStore at -20°C
Shipped InIce chest + Ice pads
Product Description

R-Venlafaxine-di-p-toluoyl-D-tartrate Salt is a derivative of (-)-Venlafaxine. Venlafaxine is a derivative of phenylethylamine which is reported to facilitate neurotransmission within the central nervous system via blocking the presynaptic reuptake of neuroamines such as serotonin (5-hydroxytryptamine; 5-HT) and noradrenaline (norepinephrine). Venlafaxine is also reported to be a weak inhibitor of dopamine reuptake.|In vitro|studies indicate that Venlafaxine does not demonstrate significant activity for muscarinic, histaminergic or α-1 adrenergic receptors. The metabolism of venlafaxine is reported to occur by cytochrome P450 (CYP) enzyme CYP2D6 yielding O-desmethylvenlafaxine. A lesser metabolite, N-desmethylvenlafaxine is produced by CYP3A4.

Names and Identifiers

IUPAC Name (2S,3S)-2,3-bis[(4-methylbenzoyl)oxy]butanedioic acid;1-[(1R)-2-(dimethylamino)-1-(4-methoxyphenyl)ethyl]cyclohexan-1-ol
INCHI InChI=1S/C20H18O8.C17H27NO2/c1-11-3-7-13(8-4-11)19(25)27-15(17(21)22)16(18(23)24)28-20(26)14-9-5-12(2)6-10-14;1-18(2)13-16(17(19)11-5-4-6-12-17)14-7-9-15(20-3)10-8-14/h3-10,15-16H,1-2H3,(H,21,22)(H,23,24);7-10,16,19H,4-6,11-13H2,1-3H3/t15-,16-;16-/m00/s1
InChi Key JFYLKWUYWDBONP-VNMAQVTLSA-N
Canonical SMILES CC1=CC=C(C=C1)C(=O)OC(C(C(=O)O)OC(=O)C2=CC=C(C=C2)C)C(=O)O.CN(C)CC(C1=CC=C(C=C1)OC)C2(CCCCC2)O
Isomeric SMILES CC1=CC=C(C=C1)C(=O)O[C@@H]([C@@H](C(=O)O)OC(=O)C2=CC=C(C=C2)C)C(=O)O.CN(C)C[C@@H](C1=CC=C(C=C1)OC)C2(CCCCC2)O
PubChem CID 12050192
Molecular Weight 663.75

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Chemical and Physical Properties

SolubilitySoluble in Methanol and Water
Melt Point(°C)120-122°C (lit.)

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Solution Calculators