R-Venlafaxine-di-p-toluoyl-D-tartrate Salt , CAS No.272788-00-8

Item Number

R357440

• Synonyms: 272788-00-8|R-Venlafaxine-di-p-toluoyl-D-tartrate Salt|(2S,3S)-2,3-bis[(4-methylbenzoyl)oxy]butanedioic acid;1-[(1R)-2-(dimethylamino)-1-(4-methoxyphenyl)ethyl]cyclohexan-1-ol|(2S,3S)-4-hydroxy-2,3-bis[(4-methylbenzoyl)oxy]-4-oxobutanoate;[(2R)-2-(1-hydro
• Storage Temp: Store at -20°C
• Shipped In: Ice chest + Ice pads

Product Description

R-Venlafaxine-di-p-toluoyl-D-tartrate Salt is a derivative of (-)-Venlafaxine. Venlafaxine is a derivative of phenylethylamine which is reported to facilitate neurotransmission within the central nervous system via blocking the presynaptic reuptake of neuroamines such as serotonin (5-hydroxytryptamine; 5-HT) and noradrenaline (norepinephrine). Venlafaxine is also reported to be a weak inhibitor of dopamine reuptake.|In vitro|studies indicate that Venlafaxine does not demonstrate significant activity for muscarinic, histaminergic or α-1 adrenergic receptors. The metabolism of venlafaxine is reported to occur by cytochrome P450 (CYP) enzyme CYP2D6 yielding O-desmethylvenlafaxine. A lesser metabolite, N-desmethylvenlafaxine is produced by CYP3A4.