pAb; Rabbit anti Human Rab 6A Antibody; WB, IHC; Unconjugated
| SKU | Size | Availability | Price | Qty |
|---|---|---|---|---|
| Ab124088-10μl | 10μl | In stock | $69.90 | |
| Ab124088-50μl | 50μl | In stock | $189.90 | |
| Ab124088-100μl | 100μl | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $289.90 | |
| Ab124088-1ml | 1ml | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $2,819.90 |
pAb; Rabbit anti Human Rab 6A Antibody; WB, IHC; Unconjugated
| Product Name | Rab 6A Antibody - Primary antibody, specific to Rab 6A, Rabbit IgG |
|---|---|
| Synonyms | Rab-6 | Rab-6 antibody | RAB6A antibody | RAB6A_HUMAN antibody | Ras-related protein Rab-6A antibody | RAB6A | RAB6 |
| Specifications & Purity | ExactAb™, Validated, Carrier Free, 0.4 mg/mL |
| Host species | Rabbit |
| Specificity | Rab 6A |
| Immunogen | A synthetic peptide derived from human RAB6A (AA 105-139) |
| Positive Control | WB: Mouse brain, HEK293, A549, HeLa, HT-29, NIH/3T3 and C6 cell lysates. IHC: Human skin tissue. |
| Conjugation | Unconjugated |
| Grade | Carrier Free, ExactAb™, Validated |
| Product Description | Rabbit anti Human Rab 6A Antibody, Polyclonal, could be used for WB, IHC and so on. |
| Isotype | Rabbit IgG |
|---|---|
| SDS-PAGE | 150 kDa |
| Purification Method | Protein A purified |
| Form | Liquid |
| Concentration | 0.4 mg/mL |
| Storage Temp | Store at -20°C,Avoid repeated freezing and thawing |
| Shipped In | Ice chest + Ice pads |
| Stability And Storage | Store at 4℃ short term (1-2 weeks). Store at -20℃ long term (24 months). Upon delivery aliquot. Avoid freeze/thaw cycle. |
Rab 6A Antibody (Ab124088) - Western Blot
All lanes: Rab 6A Antibody (Ab124088) at 1/1000 dilution
Samples: Lysates at 20 µg per lane
Secondary: Goat Anti-Rabbit IgG H&L (HRP) (Ab170144) at 1/20000 dilution
Predicted band size: 24 kDa
Observed band size: 24 kDa
Exposure time: 4.9 s
Rab 6A Antibody (Ab124088) - IHC
Immunohistochemistry analysis of paraffin-embedded Human skin using Rab 6A Antibody (Ab124088). High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
|---|
| Application | Dilution info |
|---|---|
| WB | 1/500-1/1000 |
| IHC | 1/50 - 1/100 |
Enter Lot Number to search for COA:
To view the certificate results,please click on a Lot number.For Lot numbers from past orders,please use our order status section
| Lot Number | Certificate Type | Date | Item |
|---|---|---|---|
 ZJ24F0505938 | Certificate of Analysis | May 22, 2024 | Ab124088 |
| ZJ24F0505939 | Certificate of Analysis | May 22, 2024 | Ab124088 |
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| 3. Klaeger S, Heinzlmeir S and Wilhelm M et al. (2017) The target landscape of clinical kinase drugs.. Science, 358 (6367): [PMID:29191878] |
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| 5. Cuif, M H MH and 9 more authors.. (1999) Characterization of GAPCenA, a GTPase activating protein for Rab6, part of which associates with the centrosome.. The EMBO journal, (1): [PMID:10202141] |
| 6. Caillol, N N, Pasqualini, E E, Lloubes, R R and Lombardo, D D.. (2000) Impairment of bile salt-dependent lipase secretion in human pancreatic tumoral SOJ-6 cells.. Journal of cellular biochemistry, (14): [PMID:10996854] |
| 7. Shan, J J and 8 more authors.. (2000) Rab6c, a new member of the rab gene family, is involved in drug resistance in MCF7/AdrR cells.. Gene, (17): [PMID:11054569] |
| 8. Echard, A A and 8 more authors.. (2000) Alternative splicing of the human Rab6A gene generates two close but functionally different isoforms.. Molecular biology of the cell, [PMID:11071909] |
| 9. Matanis, Theodoros T and 11 more authors.. (2002) Bicaudal-D regulates COPI-independent Golgi-ER transport by recruiting the dynein-dynactin motor complex.. Nature cell biology, [PMID:12447383] |
| 10. Liewen, Heike H and 8 more authors.. (2005) Characterization of the human GARP (Golgi associated retrograde protein) complex.. Experimental cell research, (15): [PMID:15878329] |
| 11. Eathiraj, Sudharshan S, Pan, Xiaojing X, Ritacco, Christopher C and Lambright, David G DG.. (2005) Structural basis of family-wide Rab GTPase recognition by rabenosyn-5.. Nature, (21): [PMID:16034420] |
| 12. Bergbrede, Tim T, Pylypenko, Olena O, Rak, Alexey A and Alexandrov, Kirill K.. (2005) Structure of the extremely slow GTPase Rab6A in the GTP bound form at 1.8A resolution.. Journal of structural biology, [PMID:16332443] |
| 13. Yamane, Junko J and 6 more authors.. (2007) Functional involvement of TMF/ARA160 in Rab6-dependent retrograde membrane traffic.. Experimental cell research, (1): [PMID:17698061] |
| 14. Wanschers, Bas B and 5 more authors.. (2008) Rab6 family proteins interact with the dynein light chain protein DYNLRB1.. Cell motility and the cytoskeleton, [PMID:18044744] |
| 15. Burguete, Alondra Schweizer AS, Fenn, Timothy D TD, Brunger, Axel T AT and Pfeffer, Suzanne R SR.. (2008) Rab and Arl GTPase family members cooperate in the localization of the golgin GCC185.. Cell, (25): [PMID:18243103] |
| 16. Hennies, Hans Christian HC and 25 more authors.. (2008) Gerodermia osteodysplastica is caused by mutations in SCYL1BP1, a Rab-6 interacting golgin.. Nature genetics, [PMID:18997784] |
| 17. Recacha, Rosario R and 6 more authors.. (2009) Structural basis for recruitment of Rab6-interacting protein 1 to Golgi via a RUN domain.. Structure (London, England : 1993), (14): [PMID:19141279] |
| 18. Splinter, Daniël D and 15 more authors.. (2010) Bicaudal D2, dynein, and kinesin-1 associate with nuclear pore complexes and regulate centrosome and nuclear positioning during mitotic entry.. PLoS biology, (6): [PMID:20386726] |
| 19. Kinzel, Doris D and 10 more authors.. (2010) Pitchfork regulates primary cilia disassembly and left-right asymmetry.. Developmental cell, (20): [PMID:20643351] |
| 20. Indran, Sabarish V SV and Britt, William J WJ.. (2011) A role for the small GTPase Rab6 in assembly of human cytomegalovirus.. Journal of virology, [PMID:21411515] |
| 21. Mukherjee, Shaeri and 5 more authors.. (2011) Modulation of Rab GTPase function by a protein phosphocholine transferase.. Nature, (7): [PMID:21822290] |
| 22. Bienvenut, Willy V WV and 6 more authors.. (2012) Comparative large scale characterization of plant versus mammal proteins reveals similar and idiosyncratic N-α-acetylation features.. Molecular & cellular proteomics : MCP, [PMID:22223895] |
| 23. Van Damme, Petra P and 15 more authors.. (2012) N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB.. Proceedings of the National Academy of Sciences of the United States of America, (31): [PMID:22814378] |
| 24. Pusapati, Ganesh V GV, Luchetti, Giovanni G and Pfeffer, Suzanne R SR.. (2012) Ric1-Rgp1 complex is a guanine nucleotide exchange factor for the late Golgi Rab6A GTPase and an effector of the medial Golgi Rab33B GTPase.. The Journal of biological chemistry, (7): [PMID:23091056] |
| 25. Peeters, Kristien K and 14 more authors.. (2013) Molecular defects in the motor adaptor BICD2 cause proximal spinal muscular atrophy with autosomal-dominant inheritance.. American journal of human genetics, (6): [PMID:23664119] |
| 26. Thyrock, Anika A and 13 more authors.. (2013) A new Mint1 isoform, but not the conventional Mint1, interacts with the small GTPase Rab6.. PloS one, [PMID:23737971] |
| 27. Seifert, Wenke W and 7 more authors.. (2015) Cohen syndrome-associated protein COH1 physically and functionally interacts with the small GTPase RAB6 at the Golgi complex and directs neurite outgrowth.. The Journal of biological chemistry, (6): [PMID:25492866] |
| 28. Matsuto, Mariko M, Kano, Fumi F and Murata, Masayuki M.. (2015) Reconstitution of the targeting of Rab6A to the Golgi apparatus in semi-intact HeLa cells: A role of BICD2 in stabilizing Rab6A on Golgi membranes and a concerted role of Rab6A/BICD2 interactions in Golgi-to-ER retrograde transport.. Biochimica et biophysica acta, [PMID:25962623] |
