mAb (1565CT164.36.80); Mouse anti Human Rab11A Antibody; WB, IHC; Unconjugated
| SKU | Size | Availability | Price | Qty |
|---|---|---|---|---|
| Ab124104-10μl | 10μl | In stock | $69.90 | |
| Ab124104-50μl | 50μl | In stock | $189.90 | |
| Ab124104-100μl | 100μl | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $289.90 | |
| Ab124104-1ml | 1ml | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $2,309.90 |
mAb (1565CT164.36.80); Mouse anti Human Rab11A Antibody; WB, IHC; Unconjugated
| Product Name | Rab11A Mouse mAb - Primary antibody, specific to Rab11A, Mouse IgG1 |
|---|---|
| Synonyms | Rab-11 | YL8 | MGC1490 antibody | Rab 11 antibody | Rab 11A antibody | RAB 11A, member oncogene family antibody | Rab-11 antibody | RAB11 A antibody | RAB11 antibody | Rab11a antibody | RAB11A member RAS oncogene family antibody | Ras related protein Rab |
| Specifications & Purity | ExactAb™, Validated, Carrier Free, High performance, 0.5 mg/mL |
| Host species | Mouse |
| Specificity | Rab11A |
| Immunogen | Recombinant protein of human RAB11A (AA 1-216) |
| Positive Control | WB: HeLa, Jurkat, HEK293, A549, MCF7, NIH/3T3 and C6 cell lysates. IHC: Human brain tissue. |
| Conjugation | Unconjugated |
| Grade | Carrier Free, ExactAb™, High performance, Validated |
| Product Description | Mouse anti Human Rab11A Antibody, Monoclonal (1565CT164.36.80), could be used for WB, IHC and so on. |
| Isotype | Mouse IgG1 |
|---|---|
| Light Chain Type | kappa |
| SDS-PAGE | 150 kDa |
| Purification Method | Protein G purified |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Storage Temp | Store at -20°C,Avoid repeated freezing and thawing |
| Shipped In | Ice chest + Ice pads |
| Stability And Storage | Store at 4℃ short term (2 weeks). Store at -20℃ long term (24 months). Upon delivery aliquot. Avoid freeze/thaw cycle. |
Rab11A Mouse mAb (Ab124104) - Western Blot
All lanes: Rab11A Mouse mAb (Ab124104) at 1/4000 dilution
Samples: Lysates at 20 µg per lane
Secondary: Goat Anti-Mouse IgG H&L (HRP) (Ab179001) at 1/20000 dilution
Predicted band size: 24 kDa
Observed band size: 24 kDa
Exposure time: 22.1 s
Rab11A Mouse mAb (Ab124104) - IHC
Rab11A Mouse mAb (Ab124104) staining RAB11A in human brain sections by Immunohistochemistry. Tissue was fixed with formaldehyde and blocked with 3% BSA for 0. 5 hour at room temperature; antigen retrieval was by heat mediation with a citrate buffer (pH 6.0). Samples were incubated with Rab11A Mouse mAb (Ab124104) (1/25) for 1 hours at 37°C. A undiluted biotinylated goat polyvalent antibody was used as the secondary antibody.
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
|---|
| Application | Dilution info |
|---|---|
| IHC | 1/100-1/500 |
| WB |
1/4000
|
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To view the certificate results,please click on a Lot number.For Lot numbers from past orders,please use our order status section
| Lot Number | Certificate Type | Date | Item |
|---|---|---|---|
 ZJ24F0303554 | Certificate of Analysis | Mar 21, 2024 | Ab124104 |
| ZJ24F0303555 | Certificate of Analysis | Mar 21, 2024 | Ab124104 |
| 1. Drivas, G T GT, Shih, A A, Coutavas, E E EE, D'Eustachio, P P and Rush, M G MG.. (1991) Identification and characterization of a human homolog of the Schizosaccharomyces pombe ras-like gene YPT-3.. Oncogene, [PMID:1704119] |
| 2. Gromov, P S PS and 5 more authors.. (1998) Human rab11a: transcription, chromosome mapping and effect on the expression levels of host GTP-binding proteins.. FEBS letters, (16): [PMID:9662449] |
| 3. Hales, C M CM and 9 more authors.. (2001) Identification and characterization of a family of Rab11-interacting proteins.. The Journal of biological chemistry, (19): [PMID:11495908] |
| 4. Lindsay, Andrew J AJ and 6 more authors.. (2002) Rab coupling protein (RCP), a novel Rab4 and Rab11 effector protein.. The Journal of biological chemistry, (5): [PMID:11786538] |
| 5. Lindsay, Andrew J AJ and McCaffrey, Mary W MW.. (2002) Rab11-FIP2 functions in transferrin recycling and associates with endosomal membranes via its COOH-terminal domain.. The Journal of biological chemistry, (26): [PMID:11994279] |
| 6. Wallace, Deborah M E DM, Lindsay, Andrew J AJ, Hendrick, Alan G AG and McCaffrey, Mary W MW.. (2002) Rab11-FIP4 interacts with Rab11 in a GTP-dependent manner and its overexpression condenses the Rab11 positive compartment in HeLa cells.. Biochemical and biophysical research communications, (20): [PMID:12470645] |
| 7. Junutula, Jagath R JR and 5 more authors.. (2004) Molecular characterization of Rab11 interactions with members of the family of Rab11-interacting proteins.. The Journal of biological chemistry, (6): [PMID:15173169] |
| 8. Peden, Andrew A AA and 5 more authors.. (2004) The RCP-Rab11 complex regulates endocytic protein sorting.. Molecular biology of the cell, [PMID:15181150] |
| 9. Lindsay, Andrew J AJ and McCaffrey, Mary W MW.. (2004) Characterisation of the Rab binding properties of Rab coupling protein (RCP) by site-directed mutagenesis.. FEBS letters, (30): [PMID:15280022] |
| 10. Lindsay, Andrew J AJ and McCaffrey, Mary W MW.. (2004) The C2 domains of the class I Rab11 family of interacting proteins target recycling vesicles to the plasma membrane.. Journal of cell science, (1): [PMID:15304524] |
| 11. Wilson, Gayle M GM and 9 more authors.. (2005) The FIP3-Rab11 protein complex regulates recycling endosome targeting to the cleavage furrow during late cytokinesis.. Molecular biology of the cell, [PMID:15601896] |
| 12. Lock, John G JG and Stow, Jennifer L JL.. (2005) Rab11 in recycling endosomes regulates the sorting and basolateral transport of E-cadherin.. Molecular biology of the cell, [PMID:15689490] |
| 13. Pasqualato, Sebastiano S and Cherfils, Jacqueline J.. (2005) Crystallographic evidence for substrate-assisted GTP hydrolysis by a small GTP binding protein.. Structure (London, England : 1993), [PMID:15837192] |
| 14. Eathiraj, Sudharshan S, Pan, Xiaojing X, Ritacco, Christopher C and Lambright, David G DG.. (2005) Structural basis of family-wide Rab GTPase recognition by rabenosyn-5.. Nature, (21): [PMID:16034420] |
| 15. Fielding, Andrew B AB and 9 more authors.. (2005) Rab11-FIP3 and FIP4 interact with Arf6 and the exocyst to control membrane traffic in cytokinesis.. The EMBO journal, (5): [PMID:16148947] |
| 16. Zody, Michael C MC and 68 more authors.. (2006) Analysis of the DNA sequence and duplication history of human chromosome 15.. Nature, (30): [PMID:16572171] |
| 17. Jagoe, William N WN and 5 more authors.. (2006) Crystal structure of rab11 in complex with rab11 family interacting protein 2.. Structure (London, England : 1993), [PMID:16905101] |
| 18. Eathiraj, Sudharshan S, Mishra, Ashwini A, Prekeris, Rytis R and Lambright, David G DG.. (2006) Structural basis for Rab11-mediated recruitment of FIP3 to recycling endosomes.. Journal of molecular biology, (24): [PMID:17007872] |
| 19. Shiba, Tomoo T and 6 more authors.. (2006) Structural basis for Rab11-dependent membrane recruitment of a family of Rab11-interacting protein 3 (FIP3)/Arfophilin-1.. Proceedings of the National Academy of Sciences of the United States of America, (17): [PMID:17030804] |
| 20. Shirane, Michiko M and Nakayama, Keiichi I KI.. (2006) Protrudin induces neurite formation by directional membrane trafficking.. Science (New York, N.Y.), (3): [PMID:17082457] |
| 21. Westlake, Christopher J CJ and 7 more authors.. (2007) Identification of Rab11 as a small GTPase binding protein for the Evi5 oncogene.. Proceedings of the National Academy of Sciences of the United States of America, (23): [PMID:17229837] |
| 22. Swiatecka-Urban, Agnieszka A and 11 more authors.. (2007) Myosin Vb is required for trafficking of the cystic fibrosis transmembrane conductance regulator in Rab11a-specific apical recycling endosomes in polarized human airway epithelial cells.. The Journal of biological chemistry, (10): [PMID:17462998] |
| 23. Pohl, Christian C and Jentsch, Stefan S.. (2008) Final stages of cytokinesis and midbody ring formation are controlled by BRUCE.. Cell, (7): [PMID:18329369] |
| 24. Chu, Bei-Bei BB and 7 more authors.. (2009) Requirement of myosin Vb.Rab11a.Rab11-FIP2 complex in cholesterol-regulated translocation of NPC1L1 to the cell surface.. The Journal of biological chemistry, (14): [PMID:19542231] |
| 25. Cullinane, Andrew R AR and 24 more authors.. (2010) Mutations in VIPAR cause an arthrogryposis, renal dysfunction and cholestasis syndrome phenotype with defects in epithelial polarization.. Nature genetics, [PMID:20190753] |
| 26. Seto, Shintaro S, Tsujimura, Kunio K and Koide, Yukio Y.. (2011) Rab GTPases regulating phagosome maturation are differentially recruited to mycobacterial phagosomes.. Traffic (Copenhagen, Denmark), [PMID:21255211] |
| 27. Roland, Joseph T JT and 5 more authors.. (2011) Rab GTPase-Myo5B complexes control membrane recycling and epithelial polarization.. Proceedings of the National Academy of Sciences of the United States of America, (15): [PMID:21282656] |
| 28. Matsuzaki, Fumiko F, Shirane, Michiko M, Matsumoto, Masaki M and Nakayama, Keiichi I KI.. (2011) Protrudin serves as an adaptor molecule that connects KIF5 and its cargoes in vesicular transport during process formation.. Molecular biology of the cell, [PMID:21976701] |
| 29. Longatti, Andrea A and 5 more authors.. (2012) TBC1D14 regulates autophagosome formation via Rab11- and ULK1-positive recycling endosomes.. The Journal of cell biology, (28): [PMID:22613832] |
| 30. Lee, YuKyung Y and 5 more authors.. (2013) UNC119a bridges the transmission of Fyn signals to Rab11, leading to the completion of cytokinesis.. Cell cycle (Georgetown, Tex.), (15): [PMID:23535298] |
| 31. Gruber, Robert R and 18 more authors.. (2017) Autosomal Recessive Keratoderma-Ichthyosis-Deafness (ARKID) Syndrome Is Caused by VPS33B Mutations Affecting Rab Protein Interaction and Collagen Modification.. The Journal of investigative dermatology, [PMID:28017832] |
| 32. Sobajima, Tomoaki T and 5 more authors.. (2018) The Rab11-binding protein RELCH/KIAA1468 controls intracellular cholesterol distribution.. The Journal of cell biology, (7): [PMID:29514919] |
| 33. Jenkins, Meredith L ML and 8 more authors.. (2018) Structural determinants of Rab11 activation by the guanine nucleotide exchange factor SH3BP5.. Nature communications, (14): [PMID:30217979] |
| 34. Serwas, Nina K NK and 40 more authors.. (2019) Human DEF6 deficiency underlies an immunodeficiency syndrome with systemic autoimmunity and aberrant CTLA-4 homeostasis.. Nature communications, (15): [PMID:31308374] |
| 35. Serwas, Nina K and 41 more authors.. (2019) Publisher Correction: Human DEF6 deficiency underlies an immunodeficiency syndrome with systemic autoimmunity and aberrant CTLA-4 homeostasis.. Nature communications, (2): [PMID:31578334] |
| 36. Gan, Jiyao and 10 more authors.. (2020) The Salmonella Effector SseK3 Targets Small Rab GTPases.. Frontiers in cellular and infection microbiology, [PMID:32974215] |
