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(Rac)-BRD0705 - 10mM in DMSO, high purity , CAS No.1597440-03-3(DMSO)

  • 10mM in DMSO
Item Number
B655690
Grouped product items
SKUSizeAvailabilityPrice Qty
B655690-1ml
1ml
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$318.90
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Basic Description

Specifications & Purity10mM in DMSO
Storage TempStore at -80°C
Shipped InIce chest + Ice pads
Product Description

(Rac)-BRD0705 is a less active racemate of BRD0705. BRD0705 is a potent, paralog selective and orally active GSK3α inhibitor with an IC 50 of 66 nM and a K d of 4.8 μM. BRD0705 displays increased selectivity for GSK3α (8-fold) versus GSK3β (IC 50 of 515 nM). BRD0705 can be used for acute myeloid leukemia (AML).

Names and Identifiers

Canonical SMILES CCC1(C2=C(NC3=C1C(=O)CC(C3)(C)C)NN=C2)C4=CC=CC=C4
Molecular Weight 321.42

Certificates

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Solution Calculators