| SKU | Size | Availability | Price | Qty |
|---|---|---|---|---|
| F650266-5mg | 5mg | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $300.90 |
| Synonyms | 1,6-Naphthyridine-3-carboxamide, 4-(4-cyano-2-methoxyphenyl)-5-ethoxy-1,4-dihydro-2,8-dimethyl- | CS-0077343 | SCHEMBL18583516 | AKOS040756444 | DTXSID201035670 | 1,6-Naphthyridine-3-carboxamide, 4-(4-cyano-2-methoxyphenyl)-5-ethoxy-1,4-dihydro-2,8-dimeth |
|---|---|
| Specifications & Purity | ≥99% |
| Biochemical and Physiological Mechanisms | (Rac)-Finerenone ((Rac)-BAY 94-8862) is the racemate of Finerenone. Finerenone is a third-generation, selective, and orally available nonsteroidal mineralocorticoid receptor (MR) antagonist (IC 50 =18 nM). Finerenone displays excellent selectivity versus |
| Storage Temp | Store at -20°C |
| Shipped In | Ice chest + Ice pads |
| Product Description | (Rac)-Finerenone ((Rac)-BAY 94-8862) is the racemate of Finerenone. Finerenone is a third-generation, selective, and orally available nonsteroidal mineralocorticoid receptor (MR) antagonist (IC 50 =18 nM). Finerenone displays excellent selectivity versus glucocorticoid receptor (GR), androgen receptor (AR), and progesterone receptor (>500-fold). Form:Solid |
| IUPAC Name | 4-(4-cyano-2-methoxyphenyl)-5-ethoxy-2,8-dimethyl-1,4-dihydro-1,6-naphthyridine-3-carboxamide |
|---|---|
| INCHI | InChI=1S/C21H22N4O3/c1-5-28-21-18-17(14-7-6-13(9-22)8-15(14)27-4)16(20(23)26)12(3)25-19(18)11(2)10-24-21/h6-8,10,17,25H,5H2,1-4H3,(H2,23,26) |
| InChi Key | BTBHLEZXCOBLCY-UHFFFAOYSA-N |
| Canonical SMILES | CCOC1=NC=C(C2=C1C(C(=C(N2)C)C(=O)N)C3=C(C=C(C=C3)C#N)OC)C |
| Isomeric SMILES | CCOC1=NC=C(C2=C1C(C(=C(N2)C)C(=O)N)C3=C(C=C(C=C3)C#N)OC)C |
| Alternate CAS | 1050477-27-4 |
| PubChem CID | 24993045 |
| Molecular Weight | 378.42 |
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| Solubility | DMSO : 62.5 mg/mL (165.16 mM; Need ultrasonic) |
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