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RAD51-IN-2 - 99%, high purity , CAS No.2301085-04-9
Basic Description Synonyms Carbamic acid, N-(3-(((1,1-dimethylethyl)amino)sulfonyl)-4-(2-(trans-4-(((1-methylethoxy)carbonyl)amino)cyclohexyl)-5-thiazolyl)phenyl)-, 1-methylethyl ester | 1-Methylethyl N-[3-[[(1,1-dimethylethyl)amino]sulfonyl]-4-[2-[trans-4-[[(1-methylethoxy)carbony Specifications & Purity ≥99% Storage Temp Store at -20°C Shipped In Ice chest + Ice pads Product Description RAD51-IN-2 (compound example 67A) is a RAD51 inhibitor extracted from patent WO2019/051465A1
In Vitro
RAD51-IN-2 exhibts an EC 50 of ≤1 μM in activation-induced cytidine deaminase (AID) positive cells. MCE has not independently confirmed the accuracy of these methods. They are for reference only.
Form:Solid
IC50& Target:RAD51
Names and Identifiers IUPAC Name propan-2-yl N-[3-(tert-butylsulfamoyl)-4-[2-[4-(propan-2-yloxycarbonylamino)cyclohexyl]-1,3-thiazol-5-yl]phenyl]carbamate INCHI InChI=1S/C27H40N4O6S2/c1-16(2)36-25(32)29-19-10-8-18(9-11-19)24-28-15-22(38-24)21-13-12-20(30-26(33)37-17(3)4)14-23(21)39(34,35)31-27(5,6)7/h12-19,31H,8-11H2,1-7H3,(H,29,32)(H,30,33) InChi Key OVXFEICGTUUFPE-UHFFFAOYSA-N Canonical SMILES CC(C)OC(=O)NC1CCC(CC1)C2=NC=C(S2)C3=C(C=C(C=C3)NC(=O)OC(C)C)S(=O)(=O)NC(C)(C)C Isomeric SMILES CC(C)OC(=O)NC1CCC(CC1)C2=NC=C(S2)C3=C(C=C(C=C3)NC(=O)OC(C)C)S(=O)(=O)NC(C)(C)C Alternate CAS 2301085-04-9 PubChem CID 137542570 Molecular Weight 580.76
Chemical and Physical Properties Solubility DMSO : 100 mg/mL (172.19 mM; Need ultrasonic)
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