The store will not work correctly when cookies are disabled.
JavaScript seems to be disabled in your browser. For the best experience on our site, be sure to turn on Javascript in your browser.
Radafaxine hydrochloride - 99%, high purity , CAS No.106083-71-0
Basic Description Synonyms Radafaxine hydrochloride|106083-71-0|Radafaxine (hydrochloride)|Radafaxine HCl|(2S,3S)-Hydroxybupropion hydrochloride|GW-353162A|Radafaxine Hydrochloride [USAN]|GW353162A|SYD411HZ3S|(2S,3S)-2-(3-chlorophenyl)-3,5,5-trimethylmorpholin-2-ol;hydrochloride|Ra Specifications & Purity 99% Storage Temp Store at 2-8°C,Desiccated Shipped In Wet ice Product Description Radafaxine hydrochloride (GW-353162A) is a DAT (dopamine transporter) and NET(norepinephrine transporter) transporters inhibitor, and nAChR family modulator. Radafaxine hydrochloride (GW-353162A) is a potent metabolite of bupropion and selective for inhibiting the reuptake of norepinephrine over dopamine .
In Vitro
The relatively low potency of Radafaxine hydrochloride (GW-353162A) in blocking DAT and its slow blockade suggests that it is unlikely to have reinforcing effects. MCE has not independently confirmed the accuracy of these methods. They are for reference only.
Form:Solid
Names and Identifiers IUPAC Name (2S,3S)-2-(3-chlorophenyl)-3,5,5-trimethylmorpholin-2-ol;hydrochloride INCHI InChI=1S/C13H18ClNO2.ClH/c1-9-13(16,17-8-12(2,3)15-9)10-5-4-6-11(14)7-10;/h4-7,9,15-16H,8H2,1-3H3;1H/t9-,13+;/m0./s1 InChi Key ORXTVTDGPVINDN-BTJVGWIPSA-N Canonical SMILES CC1C(OCC(N1)(C)C)(C2=CC(=CC=C2)Cl)O.Cl Isomeric SMILES C[C@H]1[C@@](OCC(N1)(C)C)(C2=CC(=CC=C2)Cl)O.Cl WGK Germany 3 PubChem CID 9838996 Molecular Weight 292.2
Chemical and Physical Properties Solubility H2O : 33.33 mg/mL (114.07 mM; Need ultrasonic) DMSO : 25 mg/mL (85.56 mM; Need ultrasonic)
Safety and Hazards(GHS) Pictogram(s) GHS07 Signal Warning Hazard Statements H319: Causes serious eye irritation
Precautionary Statements P305+P351+P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing.
P280: Wear protective gloves/protective clothing/eye protection/face protection.
P264+P265: Wash hands [and …] thoroughly after handling. Do not touch eyes.
P337+P317: If eye irritation persists: Get medical help.
WGK Germany 3 RIDADR NONHforallmodesoftransport
Solution Calculators Molarity Calculator Determine the necessary mass, volume, or concentration for preparing a solution.
Dilution Calculator Determine the dilution needed to prepare a stock solution.
Reconstitution Calculator