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Radafaxine hydrochloride - 99%, high purity , CAS No.106083-71-0

  • ≥99%
Item Number
R646904
Grouped product items
SKUSizeAvailabilityPrice Qty
R646904-5mg
5mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$102.90
R646904-10mg
10mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$192.90

Basic Description

SynonymsRadafaxine hydrochloride|106083-71-0|Radafaxine (hydrochloride)|Radafaxine HCl|(2S,3S)-Hydroxybupropion hydrochloride|GW-353162A|Radafaxine Hydrochloride [USAN]|GW353162A|SYD411HZ3S|(2S,3S)-2-(3-chlorophenyl)-3,5,5-trimethylmorpholin-2-ol;hydrochloride|Ra
Specifications & Purity99%
Storage TempStore at 2-8°C,Desiccated
Shipped InWet ice
Product Description

Radafaxine hydrochloride (GW-353162A) is a DAT (dopamine transporter) and NET(norepinephrine transporter) transporters inhibitor, and nAChR family modulator. Radafaxine hydrochloride (GW-353162A) is a potent metabolite of bupropion and selective for inhibiting the reuptake of norepinephrine over dopamine .

In Vitro

The relatively low potency of Radafaxine hydrochloride (GW-353162A) in blocking DAT and its slow blockade suggests that it is unlikely to have reinforcing effects. MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Form:Solid

Names and Identifiers

IUPAC Name (2S,3S)-2-(3-chlorophenyl)-3,5,5-trimethylmorpholin-2-ol;hydrochloride
INCHI InChI=1S/C13H18ClNO2.ClH/c1-9-13(16,17-8-12(2,3)15-9)10-5-4-6-11(14)7-10;/h4-7,9,15-16H,8H2,1-3H3;1H/t9-,13+;/m0./s1
InChi Key ORXTVTDGPVINDN-BTJVGWIPSA-N
Canonical SMILES CC1C(OCC(N1)(C)C)(C2=CC(=CC=C2)Cl)O.Cl
Isomeric SMILES C[C@H]1[C@@](OCC(N1)(C)C)(C2=CC(=CC=C2)Cl)O.Cl
WGK Germany 3
PubChem CID 9838996
Molecular Weight 292.2

Certificates

Certificate of Analysis(COA)

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Chemical and Physical Properties

SolubilityH2O : 33.33 mg/mL (114.07 mM; Need ultrasonic) DMSO : 25 mg/mL (85.56 mM; Need ultrasonic)

Safety and Hazards(GHS)

Pictogram(s) GHS07
Signal Warning
Hazard Statements

H319:Causes serious eye irritation

Precautionary Statements

P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing.

P280:Wear protective gloves/protective clothing/eye protection/face protection.

P264+P265:Wash hands [and …] thoroughly after handling. Do not touch eyes.

P337+P317:If eye irritation persists: Get medical help.

WGK Germany 3
RIDADR NONHforallmodesoftransport

Related Documents

Solution Calculators