| SKU | Size | Availability | Price | Qty |
|---|---|---|---|---|
| R485503-200μl | 200μl | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $750.90 |
| Specifications & Purity | Ready Made Solution, 2.5mg/mL in DMSO (2.74 mM), from Streptomyces hygroscopicus |
|---|---|
| Storage Temp | Store at -20°C |
| Shipped In | Ice chest + Ice pads |
Enter Lot Number to search for COA:
| 1. Caroline E von Allmen,Nicole Schmitz,Monika Bauer,Heather J Hinton,Michael O Kurrer,Regula B Buser,Myriam Gwerder,Simone Muntwiler,Tim Sparwasser,Roger R Beerli,Martin F Bachmann. (2009-07-01) Secretory phospholipase A2-IID is an effector molecule of CD4+CD25+ regulatory T cells.. Proceedings of the National Academy of Sciences of the United States of America, 106 ((28)): (11673-11678). [PMID:19564598] |
| 2. Guoxin Ren,Jingzhou Hu,Runxiang Wang,Wei Han,Mei Zhao,Ge Zhou,Chenping Zhang,Zhiyuan Zhang. (2014-04-17) Rapamycin inhibits Toll-like receptor 4-induced pro-oncogenic function in head and neck squamous cell carcinoma.. Oncology reports, 31 ((6)): (2804-2810). [PMID:24737049] |
| 3. Bin Fang,Hongjun Xiao. (2014-05-07) Rapamycin alleviates cisplatin-induced ototoxicity in vivo.. Biochemical and biophysical research communications, 448 ((4)): (443-447). [PMID:24796670] |
| 4. Xiaohua Yu,Toshio Takayama,Shakti A Goel,Xudong Shi,Yifan Zhou,K Craig Kent,William L Murphy,Lian-Wang Guo. (2014-05-24) A rapamycin-releasing perivascular polymeric sheath produces highly effective inhibition of intimal hyperplasia.. Journal of controlled release : official journal of the Controlled Release Society, 191 (47-53). [PMID:24852098] |
| 5. X Song,A-K Dilly,S-Y Kim,H A Choudry,Y J Lee. (2014-06-06) Rapamycin-enhanced mitomycin C-induced apoptotic death is mediated through the S6K1-Bad-Bak pathway in peritoneal carcinomatosis.. Cell death & disease, 5 (e1281-e1281). [PMID:24901052] |
| 6. J T Vollrath,A Sechi,A Dreser,I Katona,D Wiemuth,J Vervoorts,M Dohmen,A Chandrasekar,J Prause,E Brauers,C M Jesse,J Weis,A Goswami. (2014-06-13) Loss of function of the ALS protein SigR1 leads to ER pathology associated with defective autophagy and lipid raft disturbances.. Cell death & disease, 5 (e1290-e1290). [PMID:24922074] |
| 7. Hui Gao,Mingzhang Ao,Haiyan Wang,Longjiang Yu. (2014-06-14) Rapamycin represses myotube hypertrophy and preserves viability of C2C12 cells during myogenesis in vitro.. Transplantation, 98 ((2)): (139-147). [PMID:24926828] |
| 8. Ling Lu,Qin Lan,Zhiyuan Li,Xiaohui Zhou,Jian Gu,Qiang Li,Julie Wang,Maogen Chen,Ya Liu,Yi Shen,David D Brand,Bernhard Ryffel,David A Horwitz,Francisco P Quismorio,Zhongmin Liu,Bin Li,Nancy J Olsen,Song Guo Zheng. (2014-08-08) Critical role of all-trans retinoic acid in stabilizing human natural regulatory T cells under inflammatory conditions.. Proceedings of the National Academy of Sciences of the United States of America, 111 ((33)): (E3432-E3440). [PMID:25099355] |
| 9. C Wu,J Zheng,X Yao,H Shan,Y Li,P Xu,X Guo. (2014-08-30) Defective autophagy in chondrocytes with Kashin-Beck disease but higher than osteoarthritis.. Osteoarthritis and cartilage, 22 ((11)): (1936-1946). [PMID:25168363] |
| 10. Shannon A Carty,Gary A Koretzky,Martha S Jordan. (2014-09-11) Interleukin-4 regulates eomesodermin in CD8+ T cell development and differentiation.. PloS one, 9 ((9)): (e106659-e106659). [PMID:25207963] |
| 11. H Artee Luchman,Owen D M Stechishin,Stephanie A Nguyen,Xueqing Q Lun,J Gregory Cairncross,Samuel Weiss. (2014-10-16) Dual mTORC1/2 blockade inhibits glioblastoma brain tumor initiating cells in vitro and in vivo and synergizes with temozolomide to increase orthotopic xenograft survival.. Clinical cancer research : an official journal of the American Association for Cancer Research, 20 ((22)): (5756-5767). [PMID:25316808] |
| 12. Fangrui Ding,Xiaoyan Zhang,Xuejuan Li,Yanqin Zhang,Baihong Li,Jie Ding. (2014-11-14) Mammalian target of rapamycin complex 2 signaling pathway regulates transient receptor potential cation channel 6 in podocytes.. PloS one, 9 ((11)): (e112972-e112972). [PMID:25393730] |
| 13. Rina Yagasaki,Tsutomu Nakahara,Asami Mori,Kenji Sakamoto,Kunio Ishii. (2014-12-03) Effects of mTOR inhibition on normal retinal vascular development in the mouse.. Experimental eye research, 129 (127-134). [PMID:25446323] |
| 14. Junhui Xing,Hongtao Liu,Huabing Yang,Rui Chen,Yuguo Chen,Jian Xu. (2014-12-30) Upregulation of Unc-51-like kinase 1 by nitric oxide stabilizes SIRT1, independent of autophagy.. PloS one, 9 ((12)): (e116165-e116165). [PMID:25541949] |
| 15. N Yuan,L Song,W Lin,Y Cao,F Xu,S Liu,A Zhang,Z Wang,X Li,Y Fang,H Zhang,W Zhao,S Hu,J Wang,S Zhang. (2015-01-24) Autophagy collaborates with ubiquitination to downregulate oncoprotein E2A/Pbx1 in B-cell acute lymphoblastic leukemia.. Blood cancer journal, 5 (e274-e274). [PMID:25615280] |
| 16. Virginia A Pedicord,Justin R Cross,Welby Montalvo-Ortiz,Martin L Miller,James P Allison. (2015-01-28) Friends not foes: CTLA-4 blockade and mTOR inhibition cooperate during CD8+ T cell priming to promote memory formation and metabolic readiness.. Journal of immunology (Baltimore, Md. : 1950), 194 ((5)): (2089-2098). [PMID:25624453] |
| 17. Maysa M Abu-Khalaf,Megan A Baumgart,Scott N Gettinger,Indukala Doddamane,David P Tuck,Shihe Hou,Nianhang Chen,Catherine Sullivan,Kimberly Lezon-Geyda,Daniel Zelterman,Christos Hatzis,Hari Deshpande,Michael P Digiovanna,Masoud Azodi,Peter E Schwartz,Lyndsay N Harris. (2015-02-05) Phase 1b study of the mammalian target of rapamycin inhibitor sirolimus in combination with nanoparticle albumin-bound paclitaxel in patients with advanced solid tumors.. Cancer, 121 ((11)): (1817-1826). [PMID:25649370] |
| 18. Qiulin Xu,Xixian Li,Yongkang Lu,Liang Shen,Jingwen Zhang,Shiping Cao,Xiaobo Huang,Jianping Bin,Yulin Liao. (2015-02-11) Pharmacological modulation of autophagy to protect cardiomyocytes according to the time windows of ischaemia/reperfusion.. British journal of pharmacology, 172 ((12)): (3072-3085). [PMID:25660104] |
| 19. C Blázquez,A Chiarlone,L Bellocchio,E Resel,P Pruunsild,D García-Rincón,M Sendtner,T Timmusk,B Lutz,I Galve-Roperh,M Guzmán. (2015-02-24) The CB₁ cannabinoid receptor signals striatal neuroprotection via a PI3K/Akt/mTORC1/BDNF pathway.. Cell death and differentiation, 22 ((10)): (1618-1629). [PMID:25698444] |
| 20. Jianling Xie,Halina Mikolajek,Craig R Pigott,Kelly J Hooper,Toby Mellows,Claire E Moore,Hafeez Mohammed,Jörn M Werner,Gareth J Thomas,Christopher G Proud. (2015-03-18) Molecular Mechanism for the Control of Eukaryotic Elongation Factor 2 Kinase by pH: Role in Cancer Cell Survival.. Molecular and cellular biology, 35 ((10)): (1805-1824). [PMID:25776553] |
| 21. Jordanna S Master,George A Thouas,Alexandra J Harvey,John R Sheedy,Natalie J Hannan,David K Gardner,Mary E Wlodek. (2015-03-27) Fathers that are born small program alterations in the next-generation preimplantation rat embryos.. The Journal of nutrition, 145 ((5)): (876-883). [PMID:25809684] |
| 22. Jing Li,Xiaocui Li,Jingpu Wang,Yuan Wang,Haifeng Qiu. (2015-04-25) MicroRNA-218 increases cellular sensitivity to Rapamycin via targeting Rictor in cervical cancer.. APMIS : acta pathologica, microbiologica, et immunologica Scandinavica, 123 ((7)): (562-570). [PMID:25908215] |
| 23. Dingguo Zhang,Cheng Wei,Jun Yao,Xiaoyan Cai,Lisheng Wang. (2015-05-10) Interleukin-10 gene-carrying bifidobacteria ameliorate murine ulcerative colitis by regulating regulatory T cell/T helper 17 cell pathway.. Experimental biology and medicine (Maywood, N.J.), 240 ((12)): (1622-1629). [PMID:25956685] |
| 24. Yi Xie,Yu Jin,Bethany L Merenick,Min Ding,Kristina M Fetalvero,Robert J Wagner,Alice Mai,Scott Gleim,David F Tucker,Morris J Birnbaum,Bryan A Ballif,Amelia K Luciano,William C Sessa,Eva M Rzucidlo,Richard J Powell,Lin Hou,Hongyu Zhao,John Hwa,Jun Yu,Kathleen A Martin. (2015-05-15) Phosphorylation of GATA-6 is required for vascular smooth muscle cell differentiation after mTORC1 inhibition.. Science signaling, 8 ((376)): (ra44-ra44). [PMID:25969542] |
| 25. Shu Chen,Ming Luo,Yuming Zhao,Yimin Zhang,Mingliang He,Wangqing Cai,Anmin Liu. (2015-05-23) Fasudil Stimulates Neurite Outgrowth and Promotes Differentiation in C17.2 Neural Stem Cells by Modulating Notch Signalling but not Autophagy.. Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, 36 ((2)): (531-541). [PMID:25997481] |
| 26. Makoto Miyara,Driss Chader,Edouard Sage,Daisuke Sugiyama,Hiroyoshi Nishikawa,Diane Bouvry,Laetitia Claër,Ravi Hingorani,Robert Balderas,Jurg Rohrer,Noel Warner,Alain Chapelier,Dominique Valeyre,Reiji Kannagi,Shimon Sakaguchi,Zahir Amoura,Guy Gorochov. (2015-05-28) Sialyl Lewis x (CD15s) identifies highly differentiated and most suppressive FOXP3high regulatory T cells in humans.. Proceedings of the National Academy of Sciences of the United States of America, 112 ((23)): (7225-7230). [PMID:26015572] |
| 27. Enrico Milan,Tommaso Perini,Massimo Resnati,Ugo Orfanelli,Laura Oliva,Andrea Raimondi,Paolo Cascio,Angela Bachi,Magda Marcatti,Fabio Ciceri,Simone Cenci. (2015-06-05) A plastic SQSTM1/p62-dependent autophagic reserve maintains proteostasis and determines proteasome inhibitor susceptibility in multiple myeloma cells.. Autophagy, 11 ((7)): (1161-1178). [PMID:26043024] |
| 28. Giulia Maria Camerino,Jean-François Desaphy,Michela De Bellis,Roberta Francesca Capogrosso,Anna Cozzoli,Maria Maddalena Dinardo,Roberta Caloiero,Kejla Musaraj,Adriano Fonzino,Elena Conte,Catherine Jagerschmidt,Florence Namour,Antonella Liantonio,Annamaria De Luca,Diana Conte Camerino,Sabata Pierno. (2015-06-13) Effects of Nandrolone in the Counteraction of Skeletal Muscle Atrophy in a Mouse Model of Muscle Disuse: Molecular Biology and Functional Evaluation.. PloS one, 10 ((6)): (e0129686-e0129686). [PMID:26066046] |
| 29. Erik Helgeland,Lars Breivik,Balindiwe J Sishi,Anna-Mart Engelbrecht,Anne K Jonassen. (2015-07-15) Intermittent insulin treatment mimics ischemic postconditioning via MitoKATP channels, ROS, and RISK.. Scandinavian cardiovascular journal : SCJ, 49 ((5)): (270-279). [PMID:26156031] |
| 30. Ling Gu,Liping Xie,Chuan Zuo,Zhigui Ma,Yanle Zhang,Yiping Zhu,Ju Gao. (2015-07-21) Targeting mTOR/p70S6K/glycolysis signaling pathway restores glucocorticoid sensitivity to 4E-BP1 null Burkitt Lymphoma.. BMC cancer, 15 (529-529). [PMID:26189041] |
| 31. Roberta L Beauchamp,Marianne F James,Patrick A DeSouza,Vilas Wagh,Wen-Ning Zhao,Justin T Jordan,Anat Stemmer-Rachamimov,Scott R Plotkin,James F Gusella,Stephen J Haggarty,Vijaya Ramesh. (2015-07-30) A high-throughput kinome screen reveals serum/glucocorticoid-regulated kinase 1 as a therapeutic target for NF2-deficient meningiomas.. Oncotarget, 6 ((19)): (16981-16997). [PMID:26219339] |
| 32. Bernadeta Szewczyk,Bartłomiej Pochwat,Anna Rafało,Agnieszka Palucha-Poniewiera,Helena Domin,Gabriel Nowak. (2015-08-25) Activation of mTOR dependent signaling pathway is a necessary mechanism of antidepressant-like activity of zinc.. Neuropharmacology, 99 (517-526). [PMID:26297535] |
| 33. Bumsup Kwon,Henry W Querfurth. (2015-09-08) Palmitate activates mTOR/p70S6K through AMPK inhibition and hypophosphorylation of raptor in skeletal muscle cells: Reversal by oleate is similar to metformin.. Biochimie, 118 (141-150). [PMID:26344902] |
| 34. Rui Xiong,Wenbo Zhou,David Siegel,Russell R A Kitson,Curt R Freed,Christopher J Moody,David Ross. (2015-09-26) A Novel Hsp90 Inhibitor Activates Compensatory Heat Shock Protein Responses and Autophagy and Alleviates Mutant A53T α-Synuclein Toxicity.. Molecular pharmacology, 88 ((6)): (1045-1054). [PMID:26405178] |
| 35. Yubin Li,Haiyan Zhu,Shaofei Wang,Xiaolu Qian,Jiajun Fan,Ziyu Wang,Ping Song,Xuesai Zhang,Weiyue Lu,Dianwen Ju. (2015-10-31) Interplay of Oxidative Stress and Autophagy in PAMAM Dendrimers-Induced Neuronal Cell Death.. Theranostics, 5 ((12)): (1363-1377). [PMID:26516373] |
| 36. Massimo Barbierato,Laura Facci,Carla Marinelli,Morena Zusso,Carla Argentini,Stephen D Skaper,Pietro Giusti. (2015-11-19) Co-ultramicronized Palmitoylethanolamide/Luteolin Promotes the Maturation of Oligodendrocyte Precursor Cells.. Scientific reports, 5 (16676-16676). [PMID:26578323] |
| 37. Abubakar Wani,Mehak Gupta,Masroor Ahmad,Aabid M Shah,Aitizaz Ul Ahsan,Parvaiz H Qazi,Fayaz Malik,Gurdarshan Singh,Parduman R Sharma,Amal Kaddoumi,Sandip B Bharate,Ram A Vishwakarma,Ajay Kumar. (2019-03-22) Alborixin clears amyloid-β by inducing autophagy through PTEN-mediated inhibition of the AKT pathway.. Autophagy, 15 ((10)): (1810-1828). [PMID:30894052] |
| 38. Audrey Der Vartanian,Marie Quétin,Stéphanie Michineau,Frédéric Auradé,Shinichiro Hayashi,Christelle Dubois,Didier Rocancourt,Bernadette Drayton-Libotte,Anikó Szegedi,Margaret Buckingham,Simon J Conway,Marianne Gervais,Frédéric Relaix. (2019-04-23) PAX3 Confers Functional Heterogeneity in Skeletal Muscle Stem Cell Responses to Environmental Stress.. Cell stem cell, 24 ((6)): (958-973). [PMID:31006622] |
| 39. Naomi X Y Ling,Adrian Kaczmarek,Ashfaqul Hoque,Elizabeth Davie,Kevin R W Ngoei,Kaitlin R Morrison,William J Smiles,Gabriella M Forte,Tingting Wang,Shervi Lie,Toby A Dite,Christopher G Langendorf,John W Scott,Jonathan S Oakhill,Janni Petersen. (2020-01-30) mTORC1 directly inhibits AMPK to promote cell proliferation under nutrient stress.. Nature metabolism, 2 ((1)): (41-49). [PMID:31993556] |
| 40. M G Yefimova,C Lefevre,A Bashamboo,C Eozenou,A Burel,M T Lavault,A C Meunier,C Pimentel,S Veau,A S Neyroud,S Jaillard,B Jégou,N Bourmeyster,C Ravel. (2020-06-13) Granulosa cells provide elimination of apoptotic oocytes through unconventional autophagy-assisted phagocytosis.. Human reproduction (Oxford, England), 35 ((6)): (1346-1362). [PMID:32531067] |
| 41. Yinfeng Xu,Yaosen Wu,Lei Wang,Chuying Qian,Qian Wang,Wei Wan. (2020-11-11) Identification of curcumin as a novel natural inhibitor of rDNA transcription.. Cell cycle (Georgetown, Tex.), 19 ((23)): (3362-3374). [PMID:33171062] |
| 42. Kim R Bridle,Amy L Sobbe,C Erika de Guzman,Nishreen Santrampurwala,Lesley A Jaskowski,Andrew D Clouston,Catherine M Campbell,V Nathan Subramaniam,Darrell H G Crawford. (2014-02-13) Lack of efficacy of mTOR inhibitors and ACE pathway inhibitors as antifibrotic agents in evolving and established fibrosis in Mdr2⁻/⁻ mice.. Liver international : official journal of the International Association for the Study of the Liver, 35 ((4)): (1451-1463). [PMID:24517519] |
| 43. I Gañán-Gómez,M C Estañ-Omaña,P Sancho,P Aller,M C Boyano-Adánez. (2014-10-18) Mechanisms of resistance to apoptosis in the human acute promyelocytic leukemia cell line NB4.. Annals of hematology, 94 ((3)): (379-392). [PMID:25322811] |
| 44. Ilona Patursky-Polischuk,Judith Kasir,Rachel Miloslavski,Zvi Hayouka,Mirit Hausner-Hanochi,Miri Stolovich-Rain,Pinchas Tsukerman,Moshe Biton,Rajini Mudhasani,Stephen N Jones,Oded Meyuhas. (2014-10-23) Reassessment of the role of TSC, mTORC1 and microRNAs in amino acids-meditated translational control of TOP mRNAs.. PloS one, 9 ((10)): (e109410-e109410). [PMID:25338081] |
| 45. Jogitha Selvarajah,Androulla Elia,Veronica A Carroll,Abdeladim Moumen. (2014-12-03) DNA damage-induced S and G2/M cell cycle arrest requires mTORC2-dependent regulation of Chk1.. Oncotarget, 6 ((1)): (427-440). [PMID:25460505] |
| 46. Zhili Deng,Xiaohua Lei,Xudong Zhang,Huishan Zhang,Shuang Liu,Qi Chen,Huimin Hu,Xinyue Wang,Lina Ning,Yujing Cao,Tongbiao Zhao,Jiaxi Zhou,Ting Chen,Enkui Duan. (2015-01-23) mTOR signaling promotes stem cell activation via counterbalancing BMP-mediated suppression during hair regeneration.. Journal of molecular cell biology, 7 ((1)): (62-72). [PMID:25609845] |
| 47. Marianna Holczer,Margita Márton,Anita Kurucz,Gábor Bánhegyi,Orsolya Kapuy. (2015-05-20) A Comprehensive Systems Biological Study of Autophagy-Apoptosis Crosstalk during Endoplasmic Reticulum Stress.. BioMed research international, 2015 (319589-319589). [PMID:25984530] |
| 48. Mei Ding,Rajneesh Malhotra,Tomas Ottosson,Magnus Lundqvist,Aman Mebrahtu,Johan Brengdahl,Ulf Gehrmann,Elisabeth Bäck,Douglas Ross-Thriepland,Ida Isaksson,Björn Magnusson,Kris F Sachsenmeier,Hanna Tegel,Sophia Hober,Mathias Uhlén,Lorenz M Mayr,Rick Davies,Johan Rockberg,Lovisa Holmberg Schiavone. (2021-08-20) Secretome screening reveals immunomodulating functions of IFNα-7, PAP and GDF-7 on regulatory T-cells.. Scientific reports, 11 ((1)): (16767-16767). [PMID:34408239] |
