Determine the necessary mass, volume, or concentration for preparing a solution.
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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SKU | Size | Availability | Price | Qty |
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R190710-100mg | 100mg | In stock | $71.90 | |
R190710-250mg | 250mg | In stock | $142.90 | |
R190710-1g | 1g | In stock | $399.90 | |
R190710-5g | 5g | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $1,399.90 |
Highly selective, irreversible MAO-B inhibitor
Synonyms | TVP1012 | (R)-2,3-dihydro-N-2-propynyl-1H-inden-1-amine | (R)-N-(2-Propynyl)-2,3-dihydroinden-1-amine | Azilect | TV-1030 | (R)-N-2-Propynyl-1-indanamine | (1R)-N-(prop-2-yn-1-yl)-2,3-dihydro-1H-inden-1-amine | AGN1135 |
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Specifications & Purity | Moligand™, ≥97% |
Storage Temp | Store at 2-8°C |
Shipped In | Wet ice |
Grade | Moligand™ |
Action Type | INHIBITOR |
Mechanism of action | Inhibitor of Monoamine oxidase B |
Note | Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details. |
Product Description |
Rasagiline (R-AGN1135) is a highly potent selective irreversible mitochondrial monoamine oxidase (MAO) inhibitor with IC50s of 4.43?nM and 412?nM for rat brain MAO B and A activity, respectively[1]. Rasagiline is a click chemistry reagent, itcontains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
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IUPAC Name | (1R)-N-prop-2-ynyl-2,3-dihydro-1H-inden-1-amine |
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INCHI | InChI=1S/C12H13N/c1-2-9-13-12-8-7-10-5-3-4-6-11(10)12/h1,3-6,12-13H,7-9H2/t12-/m1/s1 |
InChi Key | RUOKEQAAGRXIBM-GFCCVEGCSA-N |
Canonical SMILES | C#CCNC1CCC2=CC=CC=C12 |
Isomeric SMILES | C#CCN[C@@H]1CCC2=CC=CC=C12 |
PubChem CID | 3052776 |
Molecular Weight | 171.24 |
DrugBank Ligand | DB01367 |
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PubChem CID | 3052776 |
ChEMBL Ligand | CHEMBL887 |
Wikipedia | Rasagiline |
CAS Registry No. | 136236-51-6 |
PEP | rasagiline |
RCSB PDB Ligand | RAU |
DrugCentral Ligand | 3521 |
Enter Lot Number to search for COA:
Find and download the COA for your product by matching the lot number on the packaging.
Lot Number | Certificate Type | Date | Item |
---|---|---|---|
G2424392 | Certificate of Analysis | Jul 05, 2024 | R190710 |
G2424406 | Certificate of Analysis | Jul 05, 2024 | R190710 |
H2124424 | Certificate of Analysis | Jun 20, 2024 | R190710 |
H2124425 | Certificate of Analysis | Jun 20, 2024 | R190710 |
B2224286 | Certificate of Analysis | Jan 04, 2022 | R190710 |
B2224309 | Certificate of Analysis | Jan 04, 2022 | R190710 |
B2225115 | Certificate of Analysis | Jan 04, 2022 | R190710 |
B2225125 | Certificate of Analysis | Jan 04, 2022 | R190710 |
F2330021 | Certificate of Analysis | Jan 04, 2022 | R190710 |
Pictogram(s) | GHS07 |
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Signal | Warning |
Hazard Statements | H315:Causes skin irritation H319:Causes serious eye irritation H335:May cause respiratory irritation H302:Harmful if swallowed |
Precautionary Statements | P261:Avoid breathing dust/fume/gas/mist/vapors/spray. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of water. P321:Specific treatment (see ... on this label). P405:Store locked up. P501:Dispose of contents/container to ... P264:Wash hands [and …] thoroughly after handling. P271:Use only outdoors or in a well-ventilated area. P270:Do not eat, drink or smoke when using this product. P304+P340:IF INHALED: Remove person to fresh air and keep comfortable for breathing. P403+P233:Store in a well-ventilated place. Keep container tightly closed. P362+P364:Take off contaminated clothing and wash it before reuse. P330:Rinse mouth. P264+P265:Wash hands [and …] thoroughly after handling. Do not touch eyes. P301+P317:IF SWALLOWED: Get medical help. P337+P317:If eye irritation persists: Get medical help. P332+P317:If skin irritation occurs: Get medical help. P319:Get medical help if you feel unwell. |
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1. Yi-Kao Hu, Yi-Ming Liu, Xiao-Lin Bai, Chao Ma, Xun Liao. (2023) Screening of Monoamine Oxidase B Inhibitors from Fragaria nubicola by Ligand Fishing and Their Neuroprotective Effects. JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 71 (1): (512–521). [PMID:36562659] |
1. Yi-Kao Hu, Yi-Ming Liu, Xiao-Lin Bai, Chao Ma, Xun Liao. (2023) Screening of Monoamine Oxidase B Inhibitors from Fragaria nubicola by Ligand Fishing and Their Neuroprotective Effects. JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 71 (1): (512–521). [PMID:36562659] |