Ravagalimab (anti-CD40) is a CD40 antagonist (EC50: 3.7 nM). Ravagalimab (anti-CD40) can be used for research of Crohn's disease.
Purity
>95% (SDS-PAGE&SEC)
Endotoxin Level
< 1.0EU/mg
Product Properties
Isotype
Human IgG1
Light Chain Type
kappa
SDS-PAGE
146.04 kDa
Purification Method
Protein A purified
Form
Liquid
Concentration
Lot by Lot
Storage Temp
Store at -80°C,Avoid repeated freezing and thawing
Shipped In
Ice chest + Ice pads
Stability And Storage
Store at -80℃ for 24 months. Upon delivery aliquot. Avoid freeze/thaw cycle.
CAS
2050816-56-1
Images
Ravagalimab (anti-CD40) (Ab182860) - Flow Cytometry Flow Cytometry analysis of human peripheral blood lymphocytes labelling CD40 with Ravagalimab (anti-CD40) (Ab182860) conjugated with biotin (right panel) compared with Human IgG (Biotin) (Ab180314) - Isotype Control (left panel) and detected with SA-PE (rp156150).
Ravagalimab (anti-CD40) (Ab182860) - ELISA Immobilized Recombinant Human CD40 protein (rp183577) at 1.0 μg/mL can bind Ravagalimab (anti-CD40) (Ab182860) with the EC50 of 11.32 ng/mL.
Ravagalimab (anti-CD40) (Ab182860) - SEC The purity of Ravagalimab (anti-CD40) (Ab182860) is more than 95% verified by HPLC.
Ravagalimab (anti-CD40) (Ab182860) - Flow Cytometry Flow Cytometry analysis of human peripheral blood lymphocytes labelling CD40 (red) with Ravagalimab (anti-CD40) (Ab182860) conjugated with biotin and detected with SA-PE (rp156150). Blue - Isotype control, Human IgG (Biotin) (Ab180314). Black - Unlabelled control, cells without incubation with primary antibody.
Ravagalimab (anti-CD40) (Ab182860) - Flow Cytometry Flow Cytometry analysis of Raji cells labelling CD40 (red) with Ravagalimab (anti-CD40) (Ab182860). Goat Anti-Human IgG (PE) (Ab175838) at a dilution of 1/1000 was used as the secondary antibody. Blue - Isotype control, human IgG (Ab170213). Black - Unlabelled control, cells without incubation with primary antibody.
Ravagalimab (anti-CD40) (Ab182860) - Flow Cytometry Flow Cytometry analysis of Ramos cells labelling CD40 (red) with Ravagalimab (anti-CD40) (Ab182860). Goat Anti-Human IgG (PE) (Ab175838) at a dilution of 1/1000 was used as the secondary antibody. Blue - Isotype control, human IgG (Ab170213). Black - Unlabelled control, cells without incubation with primary antibody.
Associated Targets
CD40Tchem Tumor necrosis factor receptor superfamily member 5 0 Activities