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RBC8 - ≥98%(HPLC), high purity , CAS No.361185-42-4
Basic Description Synonyms 6-Amino-4-(2,5-dimethoxyphenyl)-1,4-dihydro-3-(2-naphthalenyl)pyrano[2,3-c]pyrazole-5-carbonitrile Specifications & Purity ≥98%(HPLC) Biochemical and Physiological Mechanisms RalA and RalB GTPase inhibitor (EC50~3.5μM). Inhibits the binding of Ral to RaLBP1. Exhibits no detectable inhibition of Ras or RhoA activity. Suppresses growth of xenograft tumors in mice. Cell permeable. Storage Temp Store at -20°C Shipped In Ice chest + Ice pads
Names and Identifiers IUPAC Name 6-amino-4-(2,5-dimethoxyphenyl)-3-naphthalen-2-yl-2,4-dihydropyrano[2,3-c]pyrazole-5-carbonitrile INCHI InChI=1S/C25H20N4O3/c1-30-17-9-10-20(31-2)18(12-17)21-19(13-26)24(27)32-25-22(21)23(28-29-25)16-8-7-14-5-3-4-6-15(14)11-16/h3-12,21H,27H2,1-2H3,(H,28,29) InChi Key CLMQBVUFKIKYLU-UHFFFAOYSA-N Canonical SMILES COC1=CC(=C(C=C1)OC)C2C(=C(OC3=NNC(=C23)C4=CC5=CC=CC=C5C=C4)N)C#N Isomeric SMILES COC1=CC(=C(C=C1)OC)C2C(=C(OC3=NNC(=C23)C4=CC5=CC=CC=C5C=C4)N)C#N PubChem CID 6626226 Molecular Weight 424.45
Chemical and Physical Properties Solubility Solvent:DMSO, Max Conc. mg/mL: 42.44, Max Conc. mM: 100
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G2415659