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RBC8 - 10mM in DMSO, high purity , CAS No.361185-42-4

Item Number

R423626

Grouped product items
SKU	Size	Availability	Price	Qty
R423626-1ml	1ml	Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!	$263.90

RalA and RalB inhibitor

Basic Description

Synonyms	6-Amino-4-(2,5-dimethoxyphenyl)-1,4-dihydro-3-(2-naphthalenyl)pyrano[2,3-c]pyrazole-5-carbonitrile
Specifications & Purity	10mM in DMSO
Biochemical and Physiological Mechanisms	RalA and RalB GTPase inhibitor (EC50~3.5μM). Inhibits the binding of Ral to RaLBP1. Exhibits no detectable inhibition of Ras or RhoA activity. Suppresses growth of xenograft tumors in mice. Cell permeable.
Storage Temp	Store at -80°C
Shipped In	Ice chest + Ice pads

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

IUPAC Name	6-amino-4-(2,5-dimethoxyphenyl)-3-naphthalen-2-yl-2,4-dihydropyrano[2,3-c]pyrazole-5-carbonitrile
INCHI	InChI=1S/C25H20N4O3/c1-30-17-9-10-20(31-2)18(12-17)21-19(13-26)24(27)32-25-22(21)23(28-29-25)16-8-7-14-5-3-4-6-15(14)11-16/h3-12,21H,27H2,1-2H3,(H,28,29)
InChi Key	CLMQBVUFKIKYLU-UHFFFAOYSA-N
Canonical SMILES	COC1=CC(=C(C=C1)OC)C2C(=C(OC3=NNC(=C23)C4=CC5=CC=CC=C5C=C4)N)C#N
Isomeric SMILES	COC1=CC(=C(C=C1)OC)C2C(=C(OC3=NNC(=C23)C4=CC5=CC=CC=C5C=C4)N)C#N
PubChem CID	6626226
Molecular Weight	424.45

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