| SKU | Size | Availability | Price | Qty |
|---|---|---|---|---|
| R661713-1ml | 1ml | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $110.90 |
| Specifications & Purity | 10mM in DMSO |
|---|---|
| Storage Temp | Store at -80°C |
| Shipped In | Ice chest + Ice pads |
| Product Description | RBPJ Inhibitor-1 (RIN1), the first RBPJ inhibitor, blocks the functional interaction of RBPJ with SHARP. RBPJ Inhibitor-1 (RIN1) inhibits NOTCH-dependent tumor cell proliferation. In Vitro:RIN1 inhibits the proliferation of hematologic cancer cell lines and promoted skeletal muscle diferentiation from C2C12 myoblasts. RIN1 (0.6 μM, corresponding to 3 × IC 50 ) decreases the number of MHC+ cells and increased the number of nuclei per Biological Activity:RBPJ Inhibitor-1 (RIN1), the first RBPJ inhibitor, blocks the functional interaction of RBPJ with SHARP. RBPJ Inhibitor-1 (RIN1) inhibits NOTCH-dependent tumor cell proliferation. |
| Canonical SMILES | O=C(N)C1=CC=C(C2=CC=NN2C)C=C1OC3=CC=CC=C3F |
|---|---|
| Molecular Weight | 311.31 |
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