Recombinant; Rabbit anti Human Ataxin 1 Antibody; WB; Unconjugated
| SKU | Size | Availability | Price | Qty |
|---|---|---|---|---|
| Ab089896-10μl | 10μl | In stock | $69.90 | |
| Ab089896-50μl | 50μl | In stock | $199.90 | |
| Ab089896-100μl | 100μl | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $279.90 | |
| Ab089896-1ml | 1ml | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $2,699.90 |
Recombinant; Rabbit anti Human Ataxin 1 Antibody; WB; Unconjugated
| Product Name | Recombinant Ataxin 1 Antibody - Primary antibody, specific to ATXN1, Rabbit IgG |
|---|---|
| Synonyms | ATX1 | SCA1 | Ataxin 1 | Ataxin-1 | Ataxin1 | Spinocerebellar ataxia type 1 | ATX1_HUMAN | alternative ataxin1 antibody | Ataxin-1 antibody | ATX1 antibody | ATX1_HUMAN antibody | Atxn1 antibody | D6S504E antibody | OTTHUMP00000016065 antibody | SCA1 anti |
| Specifications & Purity | ExactAb™, Validated, Recombinant, 0.7 mg/mL |
| Host species | Rabbit |
| Specificity | ATXN1 |
| Immunogen | Recombinant protein of human Ataxin 1 (AA 562-693) |
| Positive Control | WB: HEK293, HeLa and NIH/3T3 cell lysates |
| Conjugation | Unconjugated |
| Grade | ExactAb™, Recombinant, Validated |
| Product Description | Rabbit anti Human Ataxin 1 Antibody, Recombinant, could be used for WB and so on. |
| Isotype | Rabbit IgG |
|---|---|
| SDS-PAGE | 150 kDa |
| Purification Method | Antigen affinity purified |
| Form | Liquid |
| Concentration | 0.7 mg/mL |
| Storage Temp | Store at -20°C,Avoid repeated freezing and thawing |
| Shipped In | Ice chest + Ice pads |
| Stability And Storage | Store at 4°C short term (1-2 weeks). Store at -20°C long term (24 months). Upon delivery aliquot. Avoid freeze/thaw cycle. |
Recombinant Ataxin 1 Antibody (Ab089896) - Western Blot
All lanes: Recombinant Ataxin 1 Antibody (Ab089896) at 1/1000 dilution
Samples: Lysates at 20 µg per lane
Secondary: Goat Anti-Rabbit IgG H&L (HRP) (Ab170144) at 1/20000 dilution
Predicted band size: 87 kDa
Observed band size: 104 kDa
Exposure time: 20.4 s
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
|---|
| Application | Dilution info |
|---|---|
| WB | 1/500-1/1000 |
Enter Lot Number to search for COA:
To view the certificate results,please click on a Lot number.For Lot numbers from past orders,please use our order status section
| Lot Number | Certificate Type | Date | Item |
|---|---|---|---|
 ZJ24F0303799 | Certificate of Analysis | Mar 27, 2024 | Ab089896 |
| ZJ24F0303798 | Certificate of Analysis | Mar 27, 2024 | Ab089896 |
| 1. Servadio, A A and 5 more authors.. (1995) Expression analysis of the ataxin-1 protein in tissues from normal and spinocerebellar ataxia type 1 individuals.. Nature genetics, [PMID:7647801] |
| 2. Banfi, S S and 9 more authors.. (1994) Identification and characterization of the gene causing type 1 spinocerebellar ataxia.. Nature genetics, [PMID:7951322] |
| 3. Quan, F F, Janas, J J and Popovich, B W BW.. (1995) A novel CAG repeat configuration in the SCA1 gene: implications for the molecular diagnostics of spinocerebellar ataxia type 1.. Human molecular genetics, [PMID:8634720] |
| 4. Burright, E N EN and 5 more authors.. (1997) Identification of a self-association region within the SCA1 gene product, ataxin-1.. Human molecular genetics, [PMID:9097953] |
| 5. Matilla, A A and 5 more authors.. (1997) The cerebellar leucine-rich acidic nuclear protein interacts with ataxin-1.. Nature, (30): [PMID:9353121] |
| 6. Davidson, J D JD and 5 more authors.. (2000) Identification and characterization of an ataxin-1-interacting protein: A1Up, a ubiquitin-like nuclear protein.. Human molecular genetics, (22): [PMID:11001934] |
| 7. Yue, S S, Serra, H G HG, Zoghbi, H Y HY and Orr, H T HT.. (2001) The spinocerebellar ataxia type 1 protein, ataxin-1, has RNA-binding activity that is inversely affected by the length of its polyglutamine tract.. Human molecular genetics, (1): [PMID:11136710] |
| 8. Okazawa, Hitoshi H and 13 more authors.. (2002) Interaction between mutant ataxin-1 and PQBP-1 affects transcription and cell death.. Neuron, (30): [PMID:12062018] |
| 9. Hong, Sunghoi S, Kim, Sung-Jo SJ, Ka, Sojeong S, Choi, Inho I and Kang, Seongman S.. (2002) USP7, a ubiquitin-specific protease, interacts with ataxin-1, the SCA1 gene product.. Molecular and cellular neurosciences, [PMID:12093161] |
| 10. Emamian, Effat S ES and 7 more authors.. (2003) Serine 776 of ataxin-1 is critical for polyglutamine-induced disease in SCA1 transgenic mice.. Neuron, (8): [PMID:12741986] |
| 11. Chen, Yu Wai YW, Allen, Mark D MD, Veprintsev, Dmitry B DB, Löwe, Jan J and Bycroft, Mark M.. (2004) The structure of the AXH domain of spinocerebellar ataxin-1.. The Journal of biological chemistry, (30): [PMID:14583607] |
| 12. Riley, Brigit E BE, Zoghbi, Huda Y HY and Orr, Harry T HT.. (2005) SUMOylation of the polyglutamine repeat protein, ataxin-1, is dependent on a functional nuclear localization signal.. The Journal of biological chemistry, (10): [PMID:15824120] |
| 13. Mizutani, Akifumi A and 6 more authors.. (2005) Boat, an AXH domain protein, suppresses the cytotoxicity of mutant ataxin-1.. The EMBO journal, (21): [PMID:16121196] |
| 14. Dephoure, Noah N and 6 more authors.. (2008) A quantitative atlas of mitotic phosphorylation.. Proceedings of the National Academy of Sciences of the United States of America, (5): [PMID:18669648] |
| 15. Tong, Xin X and 7 more authors.. (2011) Ataxin-1 and Brother of ataxin-1 are components of the Notch signalling pathway.. EMBO reports, [PMID:21475249] |
| 16. Zhou, Houjiang H and 6 more authors.. (2013) Toward a comprehensive characterization of a human cancer cell phosphoproteome.. Journal of proteome research, (4): [PMID:23186163] |
| 17. Gennarino, Vincenzo A VA and 13 more authors.. (2015) Pumilio1 haploinsufficiency leads to SCA1-like neurodegeneration by increasing wild-type Ataxin1 levels.. Cell, (12): [PMID:25768905] |
