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Recombinant CD1c Antibody - Primary antibody, specific to CD1c, Rabbit IgG

  • ExactAb™
  • Recombinant
  • Validated
  • 0.8 mg/mL
Features and benefits
  • Short Overview:

    Recombinant; Rabbit anti Human CD1c Antibody; WB; Unconjugated

  • Species reactivity(Reacts with): Human
  • Isotype: Rabbit IgG
    Application:
  • WB
Item Number
Ab094135
Grouped product items
SKUSizeAvailabilityPrice Qty
Ab094135-10μl
10μl
In stock
$66.90
Ab094135-50μl
50μl
In stock
$199.90
Ab094135-100μl
100μl
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$299.90
Ab094135-1ml
1ml
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$2,499.90

Recombinant; Rabbit anti Human CD1c Antibody; WB; Unconjugated

View related series
Accession#:P29017 CD1C Gene ID:911

Basic Description

Product NameRecombinant CD1c Antibody - Primary antibody, specific to CD1c, Rabbit IgG
SynonymsBDCA1 antibody; CD1 antibody; CD1A antibody; CD1c antibody; CD1c antigen antibody; CD1C antigen c polypeptide antibody; CD1c molecule antibody; CD1C_HUMAN antibody; Cortical thymocyte antigen CD1C antibody; Differentiation antigen CD1 alpha 3 antibody; R7
Specifications & PurityExactAb™, Validated, Recombinant, 0.8 mg/mL
Host speciesRabbit
SpecificityCD1c
ImmunogenA synthetic peptide derived from human CD1c (AA 100-169)
Positive ControlWB: Jurkat and MOLT-4 cell lysates.
ConjugationUnconjugated
GradeExactAb™, Recombinant, Validated
Product Description

Rabbit anti Human CD1c Antibody, Recombinant, could be used for WB and so on.
Application
WB: 1/500-1/1000
Protein Function
Antigen-presenting protein that binds self and non-self lipid and glycolipid antigens and presents them to T-cell receptors on natural killer T-cells.

Product Properties

IsotypeRabbit IgG
Light Chain Typekappa
SDS-PAGE150 kDa
Purification MethodProtein A purified
FormLiquid
Concentration0.8 mg/mL
Storage TempStore at -20°C,Avoid repeated freezing and thawing
Shipped InIce chest + Ice pads
Stability And StorageStore at 4℃ short term (1-2 weeks). Store at -20℃ long term (24 months). Upon delivery aliquot. Avoid freeze/thaw cycle.

Images

Recombinant CD1c Antibody (Ab094135) - Western Blot
All lanes: Recombinant CD1c Antibody (Ab094135) at 1/1000 dilution
Samples: Lysates at 20 µg per lane
Secondary: Goat Anti-Rabbit IgG H&L (HRP) (Ab170144) at 1/20000 dilution
Predicted band size: 38 kDa
Observed band size: 40 kDa
Exposure time: 50.0 s 

Associated Targets

CD1C Tbio T-cell surface glycoprotein CD1c 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

Application

ApplicationDilution info
WB

1/500-1/1000

Certificates

Certificate of Analysis(COA)

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2 results found

Lot NumberCertificate TypeDateItem
ZJ24F0404995Certificate of AnalysisApr 29, 2024 Ab094135
ZJ24F0404994Certificate of AnalysisApr 29, 2024 Ab094135

Related Documents

References

1. Martin, L H LH, Calabi, F F, Lefebvre, F A FA, Bilsland, C A CA and Milstein, C C..  (1987)  Structure and expression of the human thymocyte antigens CD1a, CD1b, and CD1c..  Proceedings of the National Academy of Sciences of the United States of America,      [PMID:2447586]
2. Aruffo, A A and Seed, B B..  (1989)  Expression of cDNA clones encoding the thymocyte antigens CD1a, b, c demonstrates a hierarchy of exclusion in fibroblasts..  Journal of immunology (Baltimore, Md. : 1950),    (1):   [PMID:2701945]
3. Martin, L H LH, Calabi, F F and Milstein, C C..  (1986)  Isolation of CD1 genes: a family of major histocompatibility complex-related differentiation antigens..  Proceedings of the National Academy of Sciences of the United States of America,      [PMID:3097645]
4. Han, M M, Hannick, L I LI, DiBrino, M M and Robinson, M A MA..  (1999)  Polymorphism of human CD1 genes..  Tissue antigens,      [PMID:10488738]
5. Moody, D B DB and 10 more authors..  (2000)  CD1c-mediated T-cell recognition of isoprenoid glycolipids in Mycobacterium tuberculosis infection..  Nature,    (20):   [PMID:10786796]
6. Sugita, M M, van Der Wel, N N, Rogers, R A RA, Peters, P J PJ and Brenner, M B MB..  (2000)  CD1c molecules broadly survey the endocytic system..  Proceedings of the National Academy of Sciences of the United States of America,    (18):   [PMID:10890914]
7. Briken, V V, Jackman, R M RM, Watts, G F GF, Rogers, R A RA and Porcelli, S A SA..  (2000)  Human CD1b and CD1c isoforms survey different intracellular compartments for the presentation of microbial lipid antigens..  The Journal of experimental medicine,    (17):   [PMID:10899914]
8. Gregory, S G SG and 178 more authors..  (2006)  The DNA sequence and biological annotation of human chromosome 1..  Nature,    (18):   [PMID:16710414]
9. Wollscheid, Bernd B and 7 more authors..  (2009)  Mass-spectrometric identification and relative quantification of N-linked cell surface glycoproteins..  Nature biotechnology,      [PMID:19349973]
10. Scharf, Louise L and 14 more authors..  (2010)  The 2.5 Å structure of CD1c in complex with a mycobacterial lipid reveals an open groove ideally suited for diverse antigen presentation..  Immunity,    (14):   [PMID:21167756]

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