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Recombinant CHRM2/CM2 Antibody - Primary antibody, specific to CHRM2, Rabbit IgG

  • ExactAb™
  • Recombinant
  • Validated
  • 0.3 mg/mL
Features and benefits
  • Short Overview:

    Recombinant; Rabbit anti Human Muscarinic Acetylcholine Receptor 2/CM2 Antibody; WB; Unconjugated

  • Species reactivity(Reacts with): Human,Mouse,Rat
  • Isotype: Rabbit IgG
    Application:
  • WB
Item Number
Ab116536
Grouped product items
SKUSizeAvailabilityPrice Qty
Ab116536-10μl
10μl
In stock
$86.90
Ab116536-50μl
50μl
In stock
$249.90
Ab116536-100μl
100μl
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$399.90
Ab116536-1ml
1ml
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$2,699.90

Recombinant; Rabbit anti Human Muscarinic Acetylcholine Receptor 2/CM2 Antibody; WB; Unconjugated

Basic Description

Product NameRecombinant CHRM2/CM2 Antibody - Primary antibody, specific to CHRM2, Rabbit IgG
Synonyms7TM receptor; cholinergic receptor, muscarinic 2; CHRM2; FLJ43243; HM2; mAChR M2; MGC120006; MGC120007; muscarinic acetylcholine receptor M2; muscarinic M2 receptor; 7TM receptor antibody; Acetylcholine receptor, muscarinic, 2 antibody; AChR antibody; Acm
Specifications & PurityExactAb™, Validated, Recombinant, 0.3 mg/mL
Host speciesRabbit
SpecificityCHRM2
ImmunogenA synthetic peptide derived from human Muscarinic Acetylcholine Receptor 2 (AA 165-178).
Positive ControlWB: K562, Hep G2, HeLa, NIH/3T3 and C6 cell lysates.
ConjugationUnconjugated
GradeExactAb™, Recombinant, Validated
Product Description

Rabbit anti Human Muscarinic Acetylcholine Receptor 2/CM2 Antibody, Recombinant, could be used for WB and so on.
Application:
WB: 1/500-1/1000
Protein function
The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. Primary transducing effect is adenylate cyclase inhibition.

Product Properties

IsotypeRabbit IgG
SDS-PAGE150 kDa
Purification MethodImmunogen affinity purified
FormLiquid
Concentration0.3 mg/mL
Storage TempStore at -20°C,Avoid repeated freezing and thawing
Shipped InIce chest + Ice pads
Stability And StorageStore at 4°C short term (1-2 weeks). Store at -20°C long term (24 months). Upon delivery aliquot. Avoid freeze/thaw cycle.

Images

Recombinant Muscarinic Acetylcholine Receptor 2/CM2 Antibody (Ab116536) - Western Blot
All lanes: Recombinant Muscarinic Acetylcholine Receptor 2/CM2 Antibody (Ab116536) at 1/1000 dilution
Samples: Lysates at 20 µg per lane
Secondary: Goat Anti-Rabbit IgG H&L (HRP) (Ab170144) at 1/20000 dilution

Predicted band size: 52 kDa
Observed band size: 49 kDa
Exposure time: 10.5 s


Associated Targets

CHRM2 Tclin Muscarinic acetylcholine receptor M2 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

Application

ApplicationDilution info
WB

1/500-1/1000

Certificates

Certificate of Analysis(COA)

Enter Lot Number to search for COA:

To view the certificate results,please click on a Lot number.For Lot numbers from past orders,please use our order status section

2 results found

Lot NumberCertificate TypeDateItem
ZJ24F0202747Certificate of AnalysisFeb 06, 2024 Ab116536
ZJ24F0202748Certificate of AnalysisFeb 06, 2024 Ab116536

Related Documents

References

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55. Chen T, Benmohamed R, Kim J, Smith K, Amante D, Morimoto RI, Kirsch DR, Ferrante RJ, Silverman RB..  (2012)  ADME-guided design and synthesis of aryloxanyl pyrazolone derivatives to block mutant superoxide dismutase 1 (SOD1) cytotoxicity and protein aggregation: potential application for the treatment of amyotrophic lateral sclerosis..  J Med Chem,  55  (1): (515-527).  [PMID:22191331]
56. Poslusney MS, Sevel C, Utley TJ, Bridges TM, Morrison RD, Kett NR, Sheffler DJ, Niswender CM, Daniels JS, Conn PJ, Lindsley CW, Wood MR..  (2012)  Synthesis and biological characterization of a series of novel diaryl amide M₁ antagonists..  Bioorg Med Chem Lett,  22  (22): (6923-6928).  [PMID:23062550]
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