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Recombinant CIRP Antibody - Primary antibody, specific to CIRBP, Rabbit IgG

  • ExactAb™
  • Recombinant
  • Validated
  • 0.3 mg/mL
Features and benefits
  • Short Overview:

    Recombinant; Rabbit anti Human CIRP Antibody; WB, IHC; Unconjugated

  • Species reactivity(Reacts with): Human
  • Isotype: Rabbit IgG
    Application:
  • IHC
  • WB
Item Number
Ab096565
Grouped product items
SKUSizeAvailabilityPrice Qty
Ab096565-10μl
10μl
In stock
$69.90
Ab096565-50μl
50μl
In stock
$199.90
Ab096565-100μl
100μl
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$299.90
Ab096565-1ml
1ml
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$2,699.90

Recombinant; Rabbit anti Human CIRP Antibody; WB, IHC; Unconjugated

Basic Description

Product NameRecombinant CIRP Antibody - Primary antibody, specific to CIRBP, Rabbit IgG
SynonymsA18 hnRNP | A18HNRNP | cirbp | CIRBP_HUMAN | CIRP | Cold inducible RNA binding protein | Cold-inducible RNA-binding protein | Glycine rich RNA binding protein | Glycine-rich RNA-binding protein CIRP | A18 hnRNP antibody | A18HNRNP antibody | cirbp antibod
Specifications & PurityExactAb™, Validated, Recombinant, 0.3 mg/mL
Host speciesRabbit
SpecificityCIRBP
ImmunogenRecombinant protein of human CIRBP (AA 1-172)
Positive ControlWB: HeLa, Hep G2, Raji and HEK293 cell lysates. IHC: Human breast cancer tissue.
ConjugationUnconjugated
GradeExactAb™, Recombinant, Validated
Product Description

Rabbit anti Human CIRP Antibody, Recombinant, could be used for WB, IHC and so on.
Application:
WB: 1/500-1/1000
IHC: 1/50-1/100
Protein Function
Cold-inducible mRNA binding protein that plays a protective role in the genotoxic stress response by stabilizing transcripts of genes involved in cell survival. Acts as a translational activator. Seems to play an essential role in cold-induced suppression of cell proliferation. Binds specifically to the 3'-untranslated regions (3'-UTRs) of stress-responsive transcripts RPA2 and TXN. Acts as a translational repressor (By similarity). Promotes assembly of stress granules (SGs), when overexpressed.

Product Properties

IsotypeRabbit IgG
SDS-PAGE150 kDa
Purification MethodAntigen affinity purified
FormLiquid
Concentration0.3 mg/mL
Storage TempStore at -20°C,Avoid repeated freezing and thawing
Shipped InIce chest + Ice pads
Stability And StorageStore at 4°C short term (1-2 weeks). Store at -20°C long term (24 months). Upon delivery aliquot. Avoid freeze/thaw cycle.

Images

Recombinant CIRP Antibody (Ab096565) - Western Blot
All lanes: Recombinant CIRP Antibody (Ab096565) at 1/1000 dilution
Samples: Lysates at 20 µg per lane
Secondary: Goat Anti-Rabbit IgG H&L (HRP) (Ab170144) at 1/20000 dilution

Predicted band size: 19 kDa
Observed band size: 19 kDa
Exposure time: 15.1 s

Associated Targets

CIRBP Tbio Cold-inducible RNA-binding protein 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

Application

ApplicationDilution info
WB

1/500-1/1000

IHC

1/50 - 1/100

Certificates

Certificate of Analysis(COA)

Enter Lot Number to search for COA:

To view the certificate results,please click on a Lot number.For Lot numbers from past orders,please use our order status section

2 results found

Lot NumberCertificate TypeDateItem
ZJ24F0303172Certificate of AnalysisMar 13, 2024 Ab096565
ZJ24F0303171Certificate of AnalysisMar 13, 2024 Ab096565

Related Documents

References

1. Sheikh, M S MS and 6 more authors..  (1997)  Identification of several human homologs of hamster DNA damage-inducible transcripts. Cloning and characterization of a novel UV-inducible cDNA that codes for a putative RNA-binding protein..  The Journal of biological chemistry,    (17):   [PMID:9334257]
2. Nishiyama, H H and 6 more authors..  (1997)  Cloning and characterization of human CIRP (cold-inducible RNA-binding protein) cDNA and chromosomal assignment of the gene..  Gene,    (19):   [PMID:9434172]
3. Yang, C C and Carrier, F F..  (2001)  The UV-inducible RNA-binding protein A18 (A18 hnRNP) plays a protective role in the genotoxic stress response..  The Journal of biological chemistry,    (14):   [PMID:11574538]
4. Grimwood, Jane J and 97 more authors..  (2004)  The DNA sequence and biology of human chromosome 19..  Nature,    (1):   [PMID:15057824]
5. Wellmann, Sven S and 7 more authors..  (2004)  Oxygen-regulated expression of the RNA-binding proteins RBM3 and CIRP by a HIF-1-independent mechanism..  Journal of cell science,    (1):   [PMID:15075239]
6. Yang, Ruiqing R, Weber, David J DJ and Carrier, France F..  (2006)  Post-transcriptional regulation of thioredoxin by the stress inducible heterogenous ribonucleoprotein A18..  Nucleic acids research,      [PMID:16513844]
7. Dephoure, Noah N and 6 more authors..  (2008)  A quantitative atlas of mitotic phosphorylation..  Proceedings of the National Academy of Sciences of the United States of America,    (5):   [PMID:18669648]
8. Mayya, Viveka V and 7 more authors..  (2009)  Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions..  Science signaling,    (18):   [PMID:19690332]
9. Zhou, Houjiang H and 6 more authors..  (2013)  Toward a comprehensive characterization of a human cancer cell phosphoproteome..  Journal of proteome research,    (4):   [PMID:23186163]
10. Bian, Yangyang Y and 9 more authors..  (2014)  An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome..  Journal of proteomics,    (16):   [PMID:24275569]

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