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Recombinant COPS3/CSN3 Antibody - Primary antibody, specific to COPS3/CSN3, Rabbit IgG

  • ExactAb™
  • Recombinant
  • Validated
  • 1.19 mg/mL
Features and benefits
  • Short Overview:

    Recombinant; Rabbit anti Human COPS3/CSN3 Antibody; WB; Unconjugated

  • Species reactivity(Reacts with): Human,Mouse,Rat
  • Isotype: Rabbit IgG
    Application:
  • WB
Item Number
Ab097335
Grouped product items
SKUSizeAvailabilityPrice Qty
Ab097335-10μl
10μl
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$79.90
Ab097335-50μl
50μl
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$239.90
Ab097335-100μl
100μl
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$379.90
Ab097335-1ml
1ml
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$2,499.90

Recombinant; Rabbit anti Human COPS3/CSN3 Antibody; WB; Unconjugated

Basic Description

Product NameRecombinant COPS3/CSN3 Antibody - Primary antibody, specific to COPS3/CSN3, Rabbit IgG
Specifications & PurityExactAb™, Validated, Recombinant, 1.19 mg/mL
Host speciesRabbit
SpecificityCOPS3/CSN3
ImmunogenA synthetic peptide derived from human COPS3 (AA 370-423)
Positive ControlWB: HeLa, HEK293, MCF7, K562, Jurkat, A549, NIH/3T3 and C6 cell lysates.
ConjugationUnconjugated
GradeExactAb™, Recombinant, Validated
Product Description

Rabbit anti Human COPS3/CSN3 Antibody, Recombinant, could be used for WB and so on.
Application:
WB: 1/500-1/1000
Protein Function:
Component of the COP9 signalosome complex (CSN), a complex involved in various cellular and developmental processes. The CSN complex is an essential regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunits of SCF-type E3 ligase complexes, leading to decrease the Ubl ligase activity of SCF-type complexes such as SCF, CSA or DDB2. The complex is also involved in phosphorylation of p53/TP53, c-jun/JUN, IkappaBalpha/NFKBIA, ITPK1 and IRF8/ICSBP, possibly via its association with CK2 and PKD kinases. CSN-dependent phosphorylation of TP53 and JUN promotes and protects degradation by the Ubl system, respectively.

Product Properties

IsotypeRabbit IgG
Light Chain Typekappa
SDS-PAGE150 kDa
Purification MethodProtein A purified
FormLiquid
Concentration1.19 mg/mL
Storage TempStore at -20°C,Avoid repeated freezing and thawing
Shipped InIce chest + Ice pads
Stability And StorageStore at 4℃ short term (1-2 weeks). Store at -20℃ long term (24 months). Upon delivery aliquot. Avoid freeze/thaw cycle.

Images

Recombinant COPS3/CSN3 Antibody (Ab097335) - Western Blot
All lanes: Recombinant COPS3/CSN3 Antibody (Ab097335) at 1/1000 dilution
Samples: Lysates at 20 µg per lane
Secondary: Goat Anti-Rabbit IgG H&L (HRP) (Ab170144) at 1/20000 dilution
Predicted band size: 48 kDa
Observed band size: 43 kDa
Exposure time: 24.1 s

Associated Targets

COPS3 Tbio COP9 signalosome complex subunit 3 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

Application

ApplicationDilution info
WB

1/500-1/1000

Certificates

Certificate of Analysis(COA)

Enter Lot Number to search for COA:

To view the certificate results,please click on a Lot number.For Lot numbers from past orders,please use our order status section

2 results found

Lot NumberCertificate TypeDateItem
ZJ24F0708716Certificate of AnalysisJul 24, 2024 Ab097335
ZJ24F0708715Certificate of AnalysisJul 24, 2024 Ab097335

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