Recombinant CPEB1 Antibody - Primary antibody, specific to CPEB1, Rabbit IgG
Specifications & Purity
ExactAb™, Validated, Recombinant, Lot by Lot
Host species
Rabbit
Specificity
CPEB1
Immunogen
A synthesized peptide derived from human CPEB1 (AA 265-325)
Positive Control
WB: A549, K562, HeLa and SK-N-SH cell lysates.
Conjugation
Unconjugated
Grade
ExactAb™, Recombinant, Validated
Product Description
Purity
Rabbit anti Human CPEB1 Antibody, Recombinant, could be used for WB and so on. Application: WB: 1/500-1/2000 Protein Function Sequence-specific RNA-binding protein that regulates mRNA cytoplasmic polyadenylation and translation initiation during oocyte maturation, early development and at postsynapse sites of neurons. Binds to the cytoplasmic polyadenylation element (CPE), an uridine-rich sequence element (consensus sequence 5'-UUUUUAU-3') within the mRNA 3'-UTR. In absence of phosphorylation and in association with TACC3 is also involved as a repressor of translation of CPE-containing mRNA; a repression that is relieved by phosphorylation or degradation (By similarity). Involved in the transport of CPE-containing mRNA to dendrites; those mRNAs may be transported to dendrites in a translationally dormant form and translationally activated at synapses (By similarity). Its interaction with APLP1 promotes local CPE-containing mRNA polyadenylation and translation activation (By similarity). Induces the assembly of stress granules in the absence of stress.
Product Properties
Isotype
Rabbit IgG
Light Chain Type
kappa
SDS-PAGE
150 kDa
Purification Method
Protein A purified
Form
Liquid
Concentration
Lot by Lot
Storage Temp
Store at -20°C,Avoid repeated freezing and thawing
Shipped In
Ice chest + Ice pads
Stability And Storage
Store at 4°C short term (1-2 weeks). Store at -20°C long term (24 months). Upon delivery aliquot. Avoid freeze/thaw cycle.
Images
Recombinant CPEB1 Antibody (Ab097517) - Western Blot All lanes: Recombinant CPEB1 Antibody (Ab097517) at 1/2000 dilution Samples: Lysates at 20 µg per lane Secondary: Goat Anti-Rabbit IgG H&L (HRP) (Ab170144) at 1/20000 dilution
Predicted band size: 63 kDa Observed band size: 68 kDa Exposure time: 26.0 s
Associated Targets
CPEB1Tbio Cytoplasmic polyadenylation element-binding protein 1 0 Activities