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Recombinant DYNLL1/PIN Antibody - Primary antibody, specific to DYNLL1, Rabbit IgG

  • ExactAb™
  • Recombinant
  • Validated
  • 1.0 mg/mL
Features and benefits
  • Short Overview:

    Recombinant; Rabbit anti Human DYNLL1/PIN Antibody; WB, IHC; Unconjugated

  • Species reactivity(Reacts with): Human,Mouse,Rat
  • Isotype: Rabbit IgG
    Application:
  • IHC
  • WB
Item Number
Ab100668
Grouped product items
SKUSizeAvailabilityPrice Qty
Ab100668-10μl
10μl
In stock
$66.90
Ab100668-50μl
50μl
In stock
$199.90
Ab100668-100μl
100μl
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$299.90
Ab100668-1ml
1ml
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$2,699.90

Recombinant; Rabbit anti Human DYNLL1/PIN Antibody; WB, IHC; Unconjugated

Basic Description

Product NameRecombinant DYNLL1/PIN Antibody - Primary antibody, specific to DYNLL1, Rabbit IgG
Synonymscytoplasmic dynein light polypeptide; DLC1; DLC1DNCLC1; DLC8; DLC8MGC126137; DNCL1; DNCL1MGC126138; DNCLC1; dynein light chain 1, cytoplasmic; Dynein light chain LC8-type 1; dynein, cytoplasmic, light polypeptide 1; dynein, light chain, LC8-type 1,8 kDa d
Specifications & PurityExactAb™, Validated, Recombinant, 1.0 mg/mL
Host speciesRabbit
SpecificityDYNLL1
ImmunogenA synthetic peptide derived from human DYNLL1 (AA 2-14)
Positive ControlWB: HeLa, Hep G2, MCF7, NIH/3T3 and C6 cell lysates. IHC: Human colon cancer tissue.
ConjugationUnconjugated
GradeExactAb™, Recombinant, Validated
Product Description

Rabbit anti Human DYNLL1/PIN Antibody, Recombinant, could be used for WB, IHC and so on.
Application:
WB: 1/500-1/1000
IHC: 1/50-1/100
Protein Function
Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in changing or maintaining the spatial distribution of cytoskeletal structures.
Binds and inhibits the catalytic activity of neuronal nitric oxide synthase.
Promotes transactivation functions of ESR1 and plays a role in the nuclear localization of ESR1.
Regulates apoptotic activities of BCL2L11 by sequestering it to microtubules. Upon apoptotic stimuli the BCL2L11-DYNLL1 complex dissociates from cytoplasmic dynein and translocates to mitochondria and sequesters BCL2 thus neutralizing its antiapoptotic activity.

Product Properties

IsotypeRabbit IgG
SDS-PAGE150 kDa
Purification MethodImmunogen affinity purified
FormLiquid
Concentration1.0 mg/mL
Storage TempStore at -20°C,Avoid repeated freezing and thawing
Shipped InIce chest + Ice pads
Stability And StorageStore at 4°C short term (1-2 weeks). Store at -20°C long term (24 months). Upon delivery aliquot. Avoid freeze/thaw cycle.

Images

Recombinant DYNLL1/PIN Antibody (Ab100668) - Western Blot
All lanes: Recombinant DYNLL1/PIN Antibody (Ab100668) at 1/1000 dilution
Samples: Lysates at 20 µg per lane
Secondary: Goat Anti-Rabbit IgG H&L (HRP) (Ab170144) at 1/20000 dilution

Predicted band size: 10 kDa
Observed band size: 12 kDa
Exposure time: 30.0 s

Recombinant DYNLL1/PIN Antibody (Ab100668) - IHC
Immunohistochemistry analysis of paraffin-embedded Human colon cancer using Recombinant DYNLL1/PIN Antibody (Ab100668). High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.

Associated Targets

DYNLL1 Tbio Dynein light chain 1, cytoplasmic 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

Application

ApplicationDilution info
WB

1/500-1/1000

IHC

1/50 - 1/100

Certificates

Certificate of Analysis(COA)

Enter Lot Number to search for COA:

To view the certificate results,please click on a Lot number.For Lot numbers from past orders,please use our order status section

2 results found

Lot NumberCertificate TypeDateItem
ZJ24F0303274Certificate of AnalysisMar 14, 2024 Ab100668
ZJ24F0303273Certificate of AnalysisMar 14, 2024 Ab100668

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