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Recombinant EYA2 Antibody - Primary antibody, specific to EYA2, Rabbit IgG

  • ExactAb™
  • High performance
  • Recombinant
  • Validated
  • 0.6 mg/mL
Features and benefits
  • Short Overview:

    Recombinant; Rabbit anti Human EYA2 Antibody; WB; Unconjugated

  • Species reactivity(Reacts with): Human,Mouse,Rat
  • Isotype: Rabbit IgG
    Application:
  • WB
Item Number
Ab102536
Grouped product items
SKUSizeAvailabilityPrice Qty
Ab102536-10μl
10μl
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$69.90
Ab102536-1ml
1ml
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$2,699.90
Ab102536-50μl
50μl
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$199.90
Ab102536-100μl
100μl
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$309.90

Recombinant; Rabbit anti Human EYA2 Antibody; WB; Unconjugated

Basic Description

Product NameRecombinant EYA2 Antibody - Primary antibody, specific to EYA2, Rabbit IgG
Specifications & PurityExactAb™, Validated, Recombinant, High performance, 0.6 mg/mL
Host speciesRabbit
SpecificityEYA2
ImmunogenA synthetic peptide derived from human EYA2 (AA 28-40)
Positive ControlWB: HeLa, A549, U-2 OS, HEK293, NIH/3T3 and C6 cell lysates.
ConjugationUnconjugated
GradeExactAb™, High performance, Recombinant, Validated
Product Description

Rabbit anti Human EYA2 Antibody, Recombinant, could be used for WB and so on.
Application:
WB: 1/1000-1/50000
Protein Function
Tyrosine phosphatase that specifically dephosphorylates 'Tyr-142' of histone H2AX (H2AXY142ph). 'Tyr-142' phosphorylation of histone H2AX plays a central role in DNA repair and acts as a mark that distinguishes between apoptotic and repair responses to genotoxic stress. Promotes efficient DNA repair by dephosphorylating H2AX, promoting the recruitment of DNA repair complexes containing MDC1. Its function as histone phosphatase probably explains its role in transcription regulation during organogenesis. Coactivates SIX1. Seems to coactivate SIX2, SIX4 and SIX5. Together with SIX1 and DACH2 seem to be involved in myogenesis. May be involved in development of the eye. Interaction with GNAZ and GNAI2 prevents nuclear translocation and transcriptional activity.

Product Properties

IsotypeRabbit IgG
Light Chain Typekappa
SDS-PAGE150 kDa
Purification MethodProtein A purified
FormLiquid
Concentration0.6 mg/mL
Storage TempStore at -20°C,Avoid repeated freezing and thawing
Shipped InIce chest + Ice pads
Stability And StorageStore at 4°C short term (1-2 weeks). Store at -20°C long term (24 months). Upon delivery aliquot. Avoid freeze/thaw cycle.

Images

Recombinant EYA2 Antibody (Ab102536) - Western Blot
All lanes: Recombinant EYA2 Antibody (Ab102536) at 1/1000 dilution
Samples: Lysates at 20 µg per lane
Secondary: Goat Anti-Rabbit IgG H&L (HRP) (Ab170144) at 1/20000 dilution
Predicted band size: 59 kDa
Observed band size: 63 kDa
Exposure time: 10.3 s

Associated Targets

EYA2 Tbio Eyes absent homolog 2 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

Application

ApplicationDilution info
WB

1/1000-1/50000

Certificates

Certificate of Analysis(COA)

Enter Lot Number to search for COA:

To view the certificate results,please click on a Lot number.For Lot numbers from past orders,please use our order status section

2 results found

Lot NumberCertificate TypeDateItem
ZJ24F0606675Certificate of AnalysisJun 11, 2024 Ab102536
ZJ24F0606676Certificate of AnalysisJun 11, 2024 Ab102536

Related Documents

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