Recombinant Hepatitis B Virus Surface Antigen (Ad/Ay) Antibody - Primary antibody, specific to Hepatitis B Virus Surface Antigen (Ad/Ay), Mouse IgG2b
Synonyms
HBsAg antibody | HBV major surface antigen antibody | HBV surface antigen antibody | Hepatitis B Virus major surface antigen antibody | Major surface antigen antibody | S antibody
Specifications & Purity
ExactAb™, Validated, Recombinant, 0.15 mg/mL
Host species
Mouse
Specificity
Hepatitis B Virus Surface Antigen (Ad/Ay)
Positive Control
IHC: Human Hepatitis B virus infected liver tissue.
Conjugation
Unconjugated
Grade
ExactAb™, Recombinant, Validated
Product Description
Mouse anti Hepatitis B Virus Surface Antigen (Ad/Ay) Antibody, Recombinant (MyM1-HbsAg), could be used for IHC and so on. Application IHC: 1/100-1/200 Relevance Hepatitis B Virus (HBV) infection induces a disease state characterised by liver damage, inflammation and viral persistence. Infection also increases the risk of hepatocellular carcinoma. HBV belongs to the Hepadnaviridae family of viruses. Its genome consists of partially double stranded circular DNA. The DNA is enclosed in a nucleocapsid, or core antigen (HBcAg), which is surrounded by a spherical envelope (surface antigen or HBsAg). The core antigen shares its sequences with the e antigen (HBeAg) but no cross reactivity between the two proteins has been observed. The HBV genome also encodes a DNA polymerase that also acts as a reverse transcriptase. Hepatitis B infection is normally diagnosed from serological tests that detect HBsAg but as the disease progresses this antigen may no longer be present in the blood and tests for HBcAg are used. If HBsAg can be detected in the blood for longer than six months, chronic hepatitis B is diagnosed. The antigenic determinant of the protein moiety of the HBsAg determines specific characteristics of different serotypes and provides the basis of immunodetection. HBsAg has antigenic heterogeneity, specifically, two pairs of sub specific determinants, d/y and w/r allow the following combinations: adw, ayw, adr, ayr.
Product Properties
Isotype
Mouse IgG2b
Light Chain Type
kappa
SDS-PAGE
150 kDa
Purification Method
Protein A purified
Form
Liquid
Concentration
0.15 mg/mL
Storage Temp
Store at 2-8°C,Avoid repeated freezing and thawing
Shipped In
Wet ice
Stability And Storage
Store at 2-8°C long term (36 months). Upon delivery aliquot. Avoid freeze/thaw cycle.
Images
Recombinant Hepatitis B Virus Surface Antigen (Ad/Ay) Antibody (Ab107271) - IHC Immunohistochemistry analysis of paraffin-embedded human Tissue corresponding to Hepatitis B virus Hepatitis B Virus Surface Antigen labelling Hepatitis B Virus Surface Antigen (Ad/Ay) with Recombinant Hepatitis B Virus Surface Antigen (Ad/Ay) Antibody (Ab107271) at 1/200 dilution. The section was incubated with Ab107271 for 30 mins at room temperature. Perform heat mediated antigen retrieval with Tris/EDTA buffer pH 9.0 was used for antigen retrieval.
Application
Application
Dilution info
IHC
1/100 - 1/200
Certificates
Certificate of Analysis(COA)
Enter Lot Number to search for COA:
Find and download the COA for your product by matching the lot number on the packaging.
ZJ24F0505228