Recombinant HLA DMB Antibody - Primary antibody, specific to HLA-DMB, Rabbit IgG
Specifications & Purity
ExactAb™, Validated, Recombinant, Lot by Lot
Host species
Rabbit
Specificity
HLA-DMB
Immunogen
A synthetic peptide derived from human HLA DMB (AA 32-85).
Positive Control
WB: Ramos and HT-29 cell lysates.
Conjugation
Unconjugated
Grade
ExactAb™, Recombinant, Validated
Product Description
Rabbit anti Human HLA DMB Antibody, Recombinant, could be used for WB and so on. Application: WB: 1/500-1/2000 Protein Relevance: HLA-DMB belongs to the HLA class II beta chain paralogues. This class II molecule is a heterodimer consisting of an alpha (DMA) and a beta (DMB) chain, both anchored in the membrane. It is located in intracellular vesicles. DM plays a central role in the peptide loading of MHC class II molecules by helping to release the CLIP (class II-associated invariant chain peptide) molecule from the peptide binding site. Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes, dendritic cells, macrophages). The beta chain is approximately 26-28 kDa and its gene contains 6 exons. Exon one encodes the leader peptide, exons 2 and 3 encode the two extracellular domains, exon 4 encodes the transmembrane domain and exon 5 encodes the cytoplasmic tail.
Product Properties
Isotype
Rabbit IgG
Light Chain Type
kappa
SDS-PAGE
150 kDa
Purification Method
Protein A purified
Form
Liquid
Concentration
Lot by Lot
Storage Temp
Store at -20°C,Avoid repeated freezing and thawing
Shipped In
Ice chest + Ice pads
Stability And Storage
Store at 4℃ short term (1-2 weeks). Store at -20℃ long term (24 months). Upon delivery aliquot. Avoid freeze/thaw cycle.
Images
Recombinant HLA DMB Antibody (Ab108179) - Western Blot All lanes: Recombinant HLA DMB Antibody (Ab108179) at 1/1000 dilution Samples: Lysates at 20 µg per lane Secondary: Goat Anti-Rabbit IgG H&L (HRP) (Ab170144) at 1/10000 dilution
Predicted band size: 29 kDa Observed band size: 30 kDa Exposure time: 33.5 s
Associated Targets
HLA-DMBTbio HLA class II histocompatibility antigen, DM beta chain 0 Activities