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Recombinant HSPA2 Antibody - Primary antibody, specific to HSPA2, Rabbit IgG

  • ExactAb™
  • Recombinant
  • Validated
  • 0.8 mg/mL
Features and benefits
  • Short Overview:

    Recombinant; Rabbit anti Human HSPA2 Antibody; WB, IHC; Unconjugated

  • Species reactivity(Reacts with): Human,Mouse,Rat
  • Isotype: Rabbit IgG
    Application:
  • IHC
Item Number
Ab108960
Grouped product items
SKUSizeAvailabilityPrice Qty
Ab108960-10μl
10μl
In stock
$89.90
Ab108960-50μl
50μl
In stock
$269.90
Ab108960-100μl
100μl
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$399.90
Ab108960-1ml
1ml
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$2,999.90

Recombinant; Rabbit anti Human HSPA2 Antibody; WB, IHC; Unconjugated

View related series
Accession#:P54652 Gene ID:3306

Basic Description

Product NameRecombinant HSPA2 Antibody - Primary antibody, specific to HSPA2, Rabbit IgG
SynonymsHeat shock 70 kDa protein 2 | Heat shock 70 kDa protein 2 | heat shock 70kD protein 2 | heat shock 70kDa protein 2 | heat shock-related 70 kDa protein 2 | HSP70-2 | HSP70-3 | HSPA2 | 70kDa antibody | Hcp70.2 antibody | Heat shock 70 kDa protein 2 antibody
Specifications & PurityExactAb™, Validated, Recombinant, 0.8 mg/mL
Host speciesRabbit
SpecificityHSPA2
ImmunogenRecombinant protein of human HSPA2 (AA 488-637)
Positive ControlWB: A549, A431, MCF7, NIH/3T3 and C6 cell lysates. IHC: Human colon cancer tissue.
ConjugationUnconjugated
GradeExactAb™, Recombinant, Validated
Product Description

Rabbit anti Human HSPA2 Antibody, Recombinant, could be used for WB, IHC and so on.
Application:
WB: 1/500-1/1000
IHC: 1/50-1/100
Protein Function
In cooperation with other chaperones, Hsp70s stabilize preexistent proteins against aggregation and mediate the folding of newly translated polypeptides in the cytosol as well as within organelles. These chaperones participate in all these processes through their ability to recognize nonnative conformations of other proteins. They bind extended peptide segments with a net hydrophobic character exposed by polypeptides during translation and membrane translocation, or following stress-induced damage.

Product Properties

IsotypeRabbit IgG
SDS-PAGE150 kDa
Purification MethodAntigen affinity purified
FormLiquid
Concentration0.8 mg/mL
Storage TempStore at -20°C,Avoid repeated freezing and thawing
Shipped InIce chest + Ice pads
Stability And StorageStore at 4°C short term (1-2 weeks). Store at -20°C long term (24 months). Upon delivery aliquot. Avoid freeze/thaw cycle.

Images

Recombinant HSPA2 Antibody (Ab108960) - Western Blot
All lanes: Recombinant HSPA2 Antibody (Ab108960) at 1/1000 dilution
Samples: Lysates at 20 µg per lane
Secondary: Goat Anti-Rabbit IgG H&L (HRP) (Ab170144) at 1/20000 dilution

Predicted band size: 70 kDa
Observed band size: 71 kDa
Exposure time: 29.1 s

Recombinant HSPA2 Antibody (Ab108960) - IHC
Immunohistochemistry analysis of paraffin-embedded Human colon cancer using Recombinant HSPA2 Antibody (Ab108960). High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.

Associated Targets

HSPA2 Tchem Heat shock-related 70 kDa protein 2 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

Application

ApplicationDilution info
IHC

1/50 - 1/100

Certificates

Certificate of Analysis(COA)

Enter Lot Number to search for COA:

To view the certificate results,please click on a Lot number.For Lot numbers from past orders,please use our order status section

2 results found

Lot NumberCertificate TypeDateItem
ZJ24F0506061Certificate of AnalysisMay 24, 2024 Ab108960
ZJ24F0506062Certificate of AnalysisMay 24, 2024 Ab108960

Related Documents

References

1. Radons J.  (2016)  The human HSP70 family of chaperones: where do we stand?.  Cell Stress Chaperones,  21  (3): (379-404).  [PMID:26865365]
2. Wang RE, Hunt CR, Chen J, Taylor JS..  (2011)  Biotinylated quercetin as an intrinsic photoaffinity proteomics probe for the identification of quercetin target proteins..  Bioorg Med Chem,  19  (16): (4710-4720).  [PMID:21798748]
3. Bonnycastle, L L LL and 7 more authors..  (1994)  Cloning, sequencing, and mapping of the human chromosome 14 heat shock protein gene (HSPA2)..  Genomics,    (1):   [PMID:7829106]
4. Roux, A F AF, Nguyen, V T VT, Squire, J A JA and Cox, D W DW..  (1994)  A heat shock gene at 14q22: mapping and expression..  Human molecular genetics,      [PMID:7849706]
5. Jarczowski, Franziska F, Fischer, Gunter G and Edlich, Frank F..  (2008)  FKBP36 forms complexes with clathrin and Hsp72 in spermatocytes..  Biochemistry,    (1):   [PMID:18529014]
6. Wisniewska, Magdalena and 6 more authors..  (2010)  Crystal structures of the ATPase domains of four human Hsp70 isoforms: HSPA1L/Hsp70-hom, HSPA2/Hsp70-2, HSPA6/Hsp70B', and HSPA5/BiP/GRP78..  PloS one,    (11):   [PMID:20072699]
7. Jakobsson, Magnus E ME and 6 more authors..  (2013)  Identification and characterization of a novel human methyltransferase modulating Hsp70 protein function through lysine methylation..  The Journal of biological chemistry,    (27):   [PMID:23921388]

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