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Recombinant Human 4-1BB Ligand/TNFSF9 Protein

  • Bioactive
  • Carrier Free
  • ≥95%(SDS-PAGE)
Features and benefits
  • Expression System: E. coli
  • Protein Tag: N-His
  • Bioactivity: Immobilized Recombinant Human 4-1BB/TNFRSF9 Protein (rp169624) at 2.0 μg/mL can bind Recombinant Human 4-1BB Ligand/TNFSF9 Protein (rp169691) with the EC50 of 6.053 ng/mL.​
  • Endotoxin Concentration: <1 EU/μg
Item Number
rp169691
Grouped product items
SKUSizeAvailabilityPrice Qty
rp169691-10μg (Trial Size)
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10μg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$69.90
rp169691-50μg
50μg
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Production requires sourcing of materials. We appreciate your patience and understanding.
$239.90
rp169691-100μg
100μg
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$359.90
rp169691-1mg
1mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$2,599.90

Carrier Free,≥95% (SDS-PAGE), Active, E. coli, N-His tag, 71-254 aa

Basic Description

Product NameRecombinant Human 4-1BB Ligand/TNFSF9 Protein
GradeBioactive, Carrier Free
Product Description

Purity:≥95%, by SDS-PAGE visualized with Coomassie® Blue Staining.
Description:
4-1BB ligand is the high affinity ligand of 4-1BB, also known as CD137L or TNFSF9. It is shown to be a type II surface glycoprotein belonging to the TNF superfamily. Expression of 4-1BBL is restricted to APCs, such as dendritic cells, macrophages, and activated B cells. Members of the TNF-TNF receptor superfamily have been shown to play critical roles in regulating cellular activation, differentiation and apoptosis. Several studies have reported that 4-1BBL/4-1BB interaction provided a co-stimulatory signal to T cells, and increased T cell proliferation and cytokines production. In addition, 4-1BBL is involved in cancers, infectious diseases and autoimmune diseases.

Specifications & PurityCarrier Free, Bioactive, ≥95%(SDS-PAGE)
BioactivityImmobilized Recombinant Human 4-1BB/TNFRSF9 Protein (rp169624) at 2.0 μg/mL can bind Recombinant Human 4-1BB Ligand/TNFSF9 Protein (rp169691) with the EC50 of 6.053 ng/mL.​
Endotoxin Concentration<1 EU/μg
Expression SystemE. coli
Amino Acids71-254 aa
SequenceMGMKHHHHHHENLYFQGSREGPELSPDDPAGLLDLRQGMFAQLVAQNVLLIDGPLSWYSDPGLAGVSLTGGLSYKEDTKELVVAKAGVYYVFFQLELRRVVAGEGSGSVSLALHLQPLRSAAGAAALALTVDLPPASSEARNSAFGFQGRLLHLSAGQRLGVHLHTEARARHAWQLTQGATVLGLFRVTPEIPAGLPSPRSE
Protein TagN-His
Predicted molecular weight21.7 kDa
SDS-PAGE20.6 kDa, under reducing conditions; 20.6 kDa, under non-reducing conditions

Images

Recombinant Human 4-1BB Ligand/TNFSF9 Protein (rp169691) - ELISA

Measured by its binding ability in a functional ELISA. Immobilized Human 4-1BB Ligand/TNFSF9 Protein (rp169691) at 2.0 μg/mL can bind Human 4-1BB Ligand/TNFSF9-biotin with the EC₅₀ of 6.053 ng/mL.


Recombinant Human 4-1BB Ligand/TNFSF9 Protein (rp169691) - SDS-PAGE
2 μg/lane of Recombinant Human 4-1BB Ligand/TNFSF9 Protein was resolved with SDS-PAGE under reducing (R) and non-reducing (N) conditions and visualized by Coomassie® Blue staining, showing a band at 20.6 kDa.

Product Specifications

FormLyophilized
ReconstitutionWe recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute at 0.1 mg/mL in sterile distilled water. Stock solutions should be apportioned into working aliquots and stored at ≤ -20 °C. Further dilu
Storage TempStore at -20°C,Avoid repeated freezing and thawing
Shipped InIce chest + Ice pads
Stability And StorageStore at -20°C for 1 year. Avoid freeze / thaw cycle.

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Lot NumberCertificate TypeDateItem
ZJ24R0500527Certificate of AnalysisMay 10, 2024 rp169691

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