Recombinant Human B7-2/CD86 Protein, ≥95% (SDS-PAGE), high purity

Features and benefits
  • Expression System: HEK293
  • Accession #: P42081
  • Protein Tag: C-His
  • Bioactivity: Immobilized Recombinant Human CD86 at 2 μg/mL (100 μL/well) can bind Recombinant Human CTLA-4 with a linear range of 10-40 ng/mL.
  • Endotoxin Concentration: <0.1 EU/μg
Item Number
rp144144
Grouped product items
SKUSizeAvailabilityPrice Qty
rp144144-10μg
10μg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$49.90
rp144144-50μg
50μg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$129.90
rp144144-100μg
100μg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$199.90
rp144144-1mg
1mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$1,499.90

Animal Free, ≥95% (SDS-PAGE), Active, 293F, C-His tag, 26-247 aa

View related series
Accession#:P42081 B7-2 CD86 Gene ID:942

Basic Description

Product NameRecombinant Human B7-2/CD86 Protein, ≥95% (SDS-PAGE), high purity
SynonymsActivation B7-2 antigen; Activation B7-2 antigen 3; B-lymphocyte activation antigen B7-2; B-lymphocyte activation antigen B7-2 2; B7; B7 2; B7-2; B7.2; B70; B72; B72 antigen; BU63; CD28 antigen ligand 2; CD28 antigen ligand 2 2; Cd28l2; CD28LG2; CD86; CD8
GradeActiBioPure™, Animal Free, Azide Free, Bioactive, Carrier Free
Product Description

Purity

≥95% (SDS-PAGE)

Endotoxin level

<0.1 EU/μg

Function

Receptor involved in the costimulatory signal essential for T-lymphocyte proliferation and interleukin-2 production, by binding CD28 or CTLA-4. May play a critical role in the early events of T-cell activation and costimulation of naive T-cells, such as deciding between immunity and anergy that is made by T-cells within 24 hours after activation. Isoform 2 interferes with the formation of CD86 clusters, and thus acts as a negative regulator of T-cell activation.


Specifications & PurityActiBioPure™, Bioactive, Animal Free, Carrier Free, Azide Free, ≥95%(SDS-PAGE)
Purity≥95% (SDS-PAGE)
BioactivityImmobilized Recombinant Human CD86 at 2 μg/mL (100 μL/well) can bind Recombinant Human CTLA-4 with a linear range of 10-40 ng/mL.
Endotoxin Concentration<0.1 EU/μg
Expression SystemHEK293
SpeciesHuman
Amino Acids26-247 aa
SequenceLKIQAYFNETADLPCQFANSQNQSLSELVVFWQDQENLVLNEVYLGKEKFDSVHSKYMGRTSFDSDSWTLRLHNLQIKDKGLYQCIIHHKKPTGMIRIHQMNSELSVLANFSQPEIVPISNITENVYINLTCSSIHGYPEPKKMSVLLRTKNSTIEYDGVMQKSQDNVTELYDVSISLSVSFPDVTSNMTIFCILETDKTRLLSSPFSIELEDPQPPPDHIPHHHHHH
Protein TagC-His
Accession #P42081
Predicted molecular weight25 kDa
SDS-PAGE40.0 - 60.0 kDa, under reducing conditions; 40.0 - 60.0 kDa, under non-reducing conditions.

Images

Recombinant Human B7-2/CD86 Protein (rp144144) - Protein Bioactivity
Immobilized Recombinant Human B7-2/CD86 Protein (rp144144) at 2.0 µg/mL can bind Recombinant Human CTLA-4 with a linear range of 10 - 40 ng/mL.

Recombinant Human B7-2/CD86 Protein (rp144144) - SDS-PAGE
3 μg/lane of Recombinant Human B7-2/CD86 Protein was resolved with SDS-PAGE under reducing (R) and non-reducing (N) conditions and visualized by Coomassie® Blue staining, showing the band at 40.0 - 60.0 kDa.

Product Specifications

FormLyophilized
ReconstitutionReconstitute in sterile water to a concentration of 0.1-0.5 mg/ml.
Storage TempStore at -20°C,Avoid repeated freezing and thawing
Shipped InIce chest + Ice pads
Stability And StorageStore at -20~-80℃ for more than 1 year. Upon delivery aliquot. Avoid freeze/thaw cycle.

Certificates

Certificate of Analysis(COA)

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3 results found

Lot NumberCertificate TypeDateItem
ZJ24F0404960Certificate of AnalysisApr 30, 2024 rp144144
ZJ24F0404959Certificate of AnalysisApr 30, 2024 rp144144
ZJ24F0404958Certificate of AnalysisApr 30, 2024 rp144144

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