Receptor involved in the costimulatory signal essential for T-lymphocyte proliferation and interleukin-2 production, by binding CD28 or CTLA-4. May play a critical role in the early events of T-cell activation and costimulation of naive T-cells, such as deciding between immunity and anergy that is made by T-cells within 24 hours after activation. Isoform 2 interferes with the formation of CD86 clusters, and thus acts as a negative regulator of T-cell activation.
40.0 - 60.0 kDa, under reducing conditions; 40.0 - 60.0 kDa, under non-reducing conditions.
Images
Recombinant Human B7-2/CD86 Protein (rp144144) - Protein Bioactivity Immobilized Recombinant Human B7-2/CD86 Protein (rp144144) at 2.0 µg/mL can bind Recombinant Human CTLA-4 with a linear range of 10 - 40 ng/mL.
Recombinant Human B7-2/CD86 Protein (rp144144) - SDS-PAGE 3 μg/lane of Recombinant Human B7-2/CD86 Protein was resolved with SDS-PAGE under reducing (R) and non-reducing (N) conditions and visualized by Coomassie® Blue staining, showing the band at 40.0 - 60.0 kDa.
Product Specifications
Form
Lyophilized
Reconstitution
Reconstitute in sterile water to a concentration of 0.1-0.5 mg/ml.
Storage Temp
Store at -20°C,Avoid repeated freezing and thawing
Shipped In
Ice chest + Ice pads
Stability And Storage
Store at -20~-80℃ for more than 1 year. Upon delivery aliquot. Avoid freeze/thaw cycle.
Certificates
Certificate of Analysis(COA)
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