Recombinant Human CCL11/Eotaxin Protein, >95% (SDS-PAGE), high purity

Features and benefits
  • Expression System: E. coli
  • Protein Tag: No tag
  • Bioactivity: Testing in progress
  • Endotoxin Concentration: <1.0 EU/μg
Item Number
rp170419
Grouped product items
SKUSizeAvailabilityPrice Qty
rp170419-10μg (Trial Size)
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10μg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$59.90
rp170419-50μg
50μg
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Production requires sourcing of materials. We appreciate your patience and understanding.
$199.90
rp170419-100μg
100μg
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Production requires sourcing of materials. We appreciate your patience and understanding.
$299.90
rp170419-1mg
1mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$1,999.90

Carrier Free, >95% (SDS-PAGE), E. coli, No tag, 24-97 aa

Basic Description

Product NameRecombinant Human CCL11/Eotaxin Protein, >95% (SDS-PAGE), high purity
SynonymsC-C motif chemokine 11 | CCL 11 | CCL11 | CCL11_HUMAN | chemokine (C-C motif) ligand 11 | Chemokine C C motif ligand 11 | Chemokine CC Motif Ligand 11 | Chemokine ligand 11 | Eosinophil chemotactic protein | Eotaxin | eotaxin-1 | MGC22554 | SCYA 11 | SCYA
GradeActiBioPure™, Azide Free, Bioactive, Carrier Free
Product Description

Purity:>95%, by SDS-PAGE visualized with Coomassie® Blue Staining.

Description

CCL11 or chemokine (C-C motif) ligand 11 is a member of the chemokine (C-C motif) ligand family. Chemokin (C-C motif) ligand 11 is a member of the chemokine family. There are four members of the chemokine family: C-C kemokines, C kemokines, CXC kemokines and CX3C kemokines. The C-C kemokines have two cysteines nearby the amino terminus. There have been at least 27 distinct members of this subgroup reported for mammals, called C-C chemokine ligands (CCL)-1 to 28. Chemokines are a family of small chemotactic cytokines, or proteins secreted by cells. They share the same structure similarities such as small size, and the presence of four cysteine residues in conserved locations in order to form their 3-dimensional shape. Some of the chemokines are considered pro-inflammatory which can be induced to recruit cells of the immune system to a site of infection during an immune response, while others are considered homeostatic and are implied in controlling the migration of cells during normal processes of tissue maintenance and development. CCL11 is implicated in allergic responses through selectively recruiting eosinophils by inducing their chemotaxis. The effects of CCL11 are mediated by its binding to chemokine receptor. Increased CCL11 levels in blood plasma are associated with aging in mice.

Specifications & PurityActiBioPure™, Bioactive, Carrier Free, Azide Free, ≥95%(SDS-PAGE)
Purity>95% (SDS-PAGE)
BioactivityTesting in progress
Endotoxin Concentration<1.0 EU/μg
Expression SystemE. coli
Amino Acids24-97 aa
SequenceGPASVPTTCCFNLANRKIPLQRLESYRRITSGKCPQKAVIFKTKLAKDICADPKKKWVQDSMKYLDQKSPTPKP
Protein TagNo tag
N-terminal SequenceGly24
Predicted molecular weight8.4 kDa
SDS-PAGE11.4 kDa, under reducing conditions; 11.4 kDa, under non-reducing conditions

Images

Recombinant Human CCL11/Eotaxin Protein (rp170419) - SDS-PAGE
2 μg/lane of Recombinant Human CCL11/Eotaxin Protein was resolved with SDS-PAGE under reducing (R) and non-reducing (N) conditions and visualized by Coomassie® Blue staining, showing a band at 11.4 kDa.

Product Specifications

FormLyophilized
ReconstitutionWe recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute at 1.0 mg/mL in sterile distilled water. Stock solutions should be apportioned into working aliquots and stored at ≤ -20 °C. Further dilu
Storage TempStore at -20°C,Avoid repeated freezing and thawing
Shipped InIce chest + Ice pads
Stability And StorageStore at -20°C for 1 year. Avoid freeze / thaw cycle.

Certificates

Certificate of Analysis(COA)

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4 results found

Lot NumberCertificate TypeDateItem
ZJ24F0404527Certificate of AnalysisApr 22, 2024 rp170419
ZJ24F0404525Certificate of AnalysisApr 22, 2024 rp170419
ZJ24F0404528Certificate of AnalysisApr 19, 2024 rp170419
ZJ24F0404526Certificate of AnalysisApr 19, 2024 rp170419

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