Recombinant Human CCL17/TARC Protein

Features and benefits
  • Expression System: E. coli
  • Protein Tag: No tag
  • Bioactivity: Testing in progress
  • Endotoxin Concentration: <1.0 EU/μg
Item Number
rp170428
Grouped product items
SKUSizeAvailabilityPrice Qty
rp170428-10μg (Trial Size)
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10μg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$139.90
rp170428-50μg
50μg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$399.90
rp170428-100μg
100μg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$599.90
rp170428-1mg
1mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$2,999.90

Carrier Free, ≥95% (SDS-PAGE), E. coli, No tag, 24-94 aa

Basic Description

Product NameRecombinant Human CCL17/TARC Protein
GradeCarrier Free
Product Description

Chemokines are a family of small chemotactic cytokines, or proteins secreted by cells. Chemokines share the same structure similarities such as small size, and the presence of four cysteine residues in conserved locations in order to form their 3-dimensional shape. Some of the chemokines are considered pro-inflammatory which can be induced to recruit cells of the immune system to a site of infection during an immune response, while others are considered homeostatic and are implied in controlling the migration of cells during normal processes of tissue maintenance and development. There are four members of the chemokine family: C-C kemokines, C kemokines, CXC kemokines and CX3C kemokines. The C-C kemokines have two cysteines nearby the amino terminus. There have been at least 27 distinct members of this subgroup reported for mammals, called C-C chemokine ligands-1 to 28. Chemokin ligand 17 (CCL17), also known as thymus and activation regulated chemokine(TARC), is a small cytokine belonging to the C-C chemokine family. CCL17 is expressed maily in thymus and transiently in phytohemagglutinin-stimulated peripheral blood mononuclear cells. CCL17 can induce chemotaxis in T cells by binding with the chemokine receptor CCR4. 

Specifications & PurityCarrier Free, ≥95%(SDS-PAGE)
BioactivityTesting in progress
Endotoxin Concentration<1.0 EU/μg
Expression SystemE. coli
Amino Acids24-94 aa
SequenceGARGTNVGRECCLEYFKGAIPLRKLKTWYQTSEDCSRDAIVFVTVQGRAICSDPNNKRVKNAVKYLQSLERS​
Protein TagNo tag
Predicted molecular weight8.1 kDa
SDS-PAGE10.4 kDa, under reducing conditions; 11.3 kDa, under non-reducing conditions

Images

Recombinant Human CCL17/TARC Protein (rp170428) - SDS-PAGE
1 μg/lane of Recombinant Human CCL17/TARC Protein was resolved with SDS-PAGE under reducing (R) and non-reducing (N) conditions and visualized by Coomassie® Blue staining, showing a band at 10.4 kDa under reducing conditions and 11.3 kDa under non-reducing conditions.

Product Specifications

ReconstitutionWe recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute at 0.1 mg/mL in sterile distilled water. Stock solutions should be apportioned into working aliquots and stored at ≤ -20 °C. Further dilu
Storage TempStore at -20°C,Avoid repeated freezing and thawing
Shipped InIce chest + Ice pads
Stability And StorageStore at -20°C for 1 year. Avoid freeze / thaw cycle.

Certificates

Certificate of Analysis(COA)

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4 results found

Lot NumberCertificate TypeDateItem
ZJ24F0707651Certificate of AnalysisJul 05, 2024 rp170428
ZJ24F0707650Certificate of AnalysisJul 05, 2024 rp170428
ZJ24F0707649Certificate of AnalysisJul 05, 2024 rp170428
ZJ24R0600641Certificate of AnalysisJun 10, 2024 rp170428

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