| SKU | Size | Availability | Price | Qty |
|---|---|---|---|---|
| rp143746-10μg | 10μg | Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience! | $139.90 | |
| rp143746-50μg | 50μg | Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience! | $459.90 | |
| rp143746-100μg | 100μg | Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience! | $739.90 | |
| rp143746-1mg | 1mg | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $2,999.90 |
Animal Free, >96%(SDS-PAGE, HPLC), Active, E.coli, No tag, 24-92 aa
| Product Name | Recombinant Human CCL4/MIP-1 beta Protein, ＞96%(SDS-PAGE, HPLC), high purity |
|---|---|
| Synonyms | ACT2 | ACT-2 | AT744.1 | C-C motif chemokine 4 | CCL4 | chemokine (C-C motif) ligand 4 | Exodus-3 | G-26 T-lymphocyte-secreted protein | G-26 | HC21 | LAG1 | LAG-1 | Lymphocyte activation gene 1 protein | Macrophage inflammatory protein 1-beta | MIP1 beta |
| Grade | ActiBioPure™, Animal Free, Azide Free, Bioactive, Carrier Free, High Performance |
| Product Description | Purity > 96 % by SDS-PAGE and HPLC analyses. Function Monokine with inflammatory and chemokinetic properties. Binds to CCR5. One of the major HIV-suppressive factors produced by CD8+ T-cells. Recombinant MIP-1-beta induces a dose-dependent inhibition of different strains of HIV-1, HIV-2, and simian immunodeficiency virus (SIV). The processed form MIP-1-beta(3-69) retains the abilities to induce down-modulation of surface expression of the chemokine receptor CCR5 and to inhibit the CCR5-mediated entry of HIV-1 in T-cells. MIP-1-beta(3-69) is also a ligand for CCR1 and CCR2 isoform B. |
| Specifications & Purity | ActiBioPure™, Bioactive, Animal Free, Carrier Free, Azide Free, High performance, ≥96%(SDS-PAGE&HPLC) |
| Purity | ＞96%(SDS-PAGE, HPLC) |
| Bioactivity | Fully biologically active when compared to standard. The biological activity determined by a chemotaxis bioassay using human peripheral blood monocytes is in a concentration range of 5.0-20 ng/ml. |
| Endotoxin Concentration | <1.0 EU/μg |
| Expression System | E.coli |
| Species | Human |
| Amino Acids | 24-92 aa |
| Sequence | APMGSDPPTA CCFSYTARKL PRNFVVDYYE TSSLCSQPAV VFQTKRSKQV CADPSESWVQ EYVYDLELN |
| Protein Tag | No tag |
| Accession # | P13236 |
| Predicted molecular weight | 7.8 kDa |
Protein Bioactivity-Recombinant Human CCL4/MIP-1 beta Protein (rp143746)-Protein Bioactivity
Fully biologically active when compared to standard. The biological activity determined by a chemotaxis bioassay using human peripheral blood monocytes is in a concentration range of 5.0-20 ng/mL.
Recombinant Human CCL4/MIP-1 beta Protein (rp143746)-SDS-PAGE
Recombinant Human CCL4/MIP-1 beta Protein was resolved with SDS-PAGE under reducing (R) and visualized by Coomassie® Blue staining, showing a band at 7.8 kDa.
| Form | Lyophilized |
|---|---|
| Reconstitution | We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1 % BSA to a concentration of 0.1-1.0 mg/mL. Stock solutions should be apportio |
| Storage Temp | Store at -20°C,Avoid repeated freezing and thawing |
| Shipped In | Ice chest + Ice pads |
| Stability And Storage | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ℃ as supplied. 1 month, 2 to 8 ℃ under sterile conditions after reconstitution. 3 months, -20 to -70 ℃ under sterile conditions after reconstitu |
Enter Lot Number to search for COA:
Find and download the COA for your product by matching the lot number on the packaging.
| Lot Number | Certificate Type | Date | Item |
|---|---|---|---|
 ZJ23F0600408 | Certificate of Analysis | Mar 26, 2024 | rp143746 |
| ZJ23F0600409 | Certificate of Analysis | Mar 26, 2024 | rp143746 |
| ZJ23F0600410 | Certificate of Analysis | Mar 26, 2024 | rp143746 |
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