Click Here for 5% Off Your First Aladdin Purchase!

Recombinant Human CD30/TNFRSF8 Protein

  • ActiBioPure™
  • Animal Free
  • Bioactive
  • Carrier Free
  • ≥95%(SDS-PAGE)
Features and benefits
  • Expression System: HEK293
  • Protein Tag: C-His
  • Bioactivity: Immobilized Recombinant Human CD30 Protein (rp169577) at 1.0 μg/mL can bind Brentuximab (anti-TNFRSF8) (Ab170548) with the EC50 of 119.9 ng/mL.
  • Endotoxin Concentration: <1 EU/μg
Item Number
rp169577
Grouped product items
SKUSizeAvailabilityPrice Qty
rp169577-10μg (Trial Size)
Apply for free trial size(?)
Every year, as a valued customer, you have the exclusive opportunity to explore and enjoy three different trial products of your choice, absolutely free!
10μg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$139.90
rp169577-50μg
50μg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$299.90
rp169577-100μg
100μg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$439.90
rp169577-1mg
1mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$2,999.90

Animal Free, ≥95% (SDS-PAGE), Active, 293F, C-His tag, 1-379 aa

Basic Description

Product NameRecombinant Human CD30/TNFRSF8 Protein
GradeActiBioPure™, Animal Free, Bioactive, Carrier Free
Product Description

Protein Function::
CD30, also known as TNFRSF8, is a cell membrane protein of the tumor necrosis factor receptor (TNFR) superfamily. CD30 protein is expressed by activated, but not resting, T and B cells. CD30 can regulate proliferation of lymphocytes and may also play an important role in human immunodeficiency virus replication. As a regulator of apoptosis, CD30 protein induces cell death or proliferation, depending on the cell type, and has been shown to limit the proliferative potential of autoreactive CD8 effector T cells and protect the body against autoimmunity. CD30 protein expression is upregulated in various hematological malignancies, including Reed-Sternberg cells in Hodgkin's disease (HD), anaplastic large cell lymphoma (ALCL) and subsets of Non-Hodgkin's lymphomas (NHLs), and CD30 is also linked to leukocytes in patients with chronic inflammatory diseases, including lupus erythematosus, asthma, rheumatoid arthritis and atopic dermatitis (AD). 

Specifications & PurityAnimal Free, Carrier Free, Bioactive, ActiBioPure™, ≥95%(SDS-PAGE)
BioactivityImmobilized Recombinant Human CD30 Protein (rp169577) at 1.0 μg/mL can bind Brentuximab (anti-TNFRSF8) (Ab170548) with the EC50 of 119.9 ng/mL.
Endotoxin Concentration<1 EU/μg
Expression SystemHEK293
Amino Acids1-379 aa
SequenceMRVLLAALGLLFLGALRAFPQDRPFEDTCHGNPSHYYDKAVRRCCYRCPMGLFPTQQCPQRPTDCRKQCEPDYYLDEADRCTACVTCSRDDLVEKTPCAWNSSRVCECRPGMFCSTSAVNSCARCFFHSVCPAGMIVKFPGTAQKNTVCEPASPGVSPACASPENCKEPSSGTIPQAKPTPVSPATSSASTMPVRGGTRLAQEAASKLTRAPDSPSSVGRPSSDPGLSPTQPCPEGSGDCRKQCEPDYYLDEAGR
Protein TagC-His
Predicted molecular weight39.2 kDa
SDS-PAGE55.0-99.0 kDa, under reducing conditions

Images

Recombinant Human CD30/TNFRSF8 Protein (rp169577) - ELISA
Immobilized Recombinant Human CD30/TNFRSF8 Protein (rp169577) at 1.0 μg/mL can bind Brentuximab (anti-TNFRSF8) (Ab170548) with the EC₅₀ of 119.9 ng/mL.


Recombinant Human CD30/TNFRSF8 Protein (rp169577) - SDS-PAGE
3 μg/lane of Recombinant Human CD30/TNFRSF8 Protein was resolved with SDS-PAGE under reducing (R) and visualized by Coomassie® Blue staining, showing a band at 55.0-99.0 kDa under reducing conditions.

Product Specifications

ReconstitutionWe recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute at 1.0 mg/mL in sterile distilled water. Stock solutions should be apportioned into working aliquots and stored at ≤ -20 °C. Further dilu
Storage TempStore at -20°C,Avoid repeated freezing and thawing
Shipped InIce chest + Ice pads
Stability And StorageStore at -20°C for 1 year. Avoid freeze / thaw cycle.

Certificates

Certificate of Analysis(COA)

Enter Lot Number to search for COA:

To view the certificate results,please click on a Lot number.For Lot numbers from past orders,please use our order status section

4 results found

Lot NumberCertificate TypeDateItem
ZJ24F0708053Certificate of AnalysisJul 12, 2024 rp169577
ZJ24F0708052Certificate of AnalysisJul 12, 2024 rp169577
ZJ24F0708051Certificate of AnalysisJul 12, 2024 rp169577
ZJ24F0708050Certificate of AnalysisJul 12, 2024 rp169577

Related Documents

Solution Calculators