Recombinant Human CD68 Protein

Features and benefits
  • Expression System: HEK293
  • Protein Tag: C-His
  • Endotoxin Concentration: <1.0 EU/μg
Item Number
rp175904
Grouped product items
SKUSizeAvailabilityPrice Qty
rp175904-10μg (Trial Size)
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10μg
In stock
$139.90
rp175904-50μg
50μg
In stock
$399.90
rp175904-100μg
100μg
In stock
$599.90
rp175904-1mg
1mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$4,999.90

Animal Free, >90% (SDS-PAGE), 293F cell, C-His tag, 22-319 aa

Basic Description

Product NameRecombinant Human CD68 Protein
SynonymsCD_antigen: CD68 | CD68 antigen | CD68 molecule | CD68 | DKFZp686M18236 | gp110 | LAMP4 | macrophage antigen CD68 | Macrosialin | SCARD1 | SRD1 | scavenger receptor class D, member 1 | SR-D1 | CD 68 | CD68_HUMAN
GradeAnimal Free, Azide Free, Carrier Free
Product Description

Purity:>90%, by SDS-PAGE visualized with Coomassie® Blue Staining.
Description:
Macrosialin, also known as CD68 and Gp11, is a single-pass type I membrane protein which belongs to theLAMP family. CD68 is highly expressed by blood monocytes and tissue macrophages. It is also expressed in lymphocytes, fibroblasts and endothelial cells. CD68 is expressed in many tumor cell lines which could allow them to attach to selectins on vascular endothelium, facilitating their dissemination to secondary sites. CD68 plays a role in phagocytic activities of tissue macrophages, both in intracellular lysosomal metabolism and extracellular cell-cell and cell-pathogen interactions. It is a commonly used marker for macrophages. However, a number of studies have shown that CD68 antibodies react with other hematopoietic and non-hematopoietic cell types, suggesting that CD68 may not be a macrophage-specific antigen. CD68 binds to tissue- and organ-specific lectins or selectins, allowing homing of macrophage subsets to particular sites. Rapid recirculation of CD68 from endosomes and lysosomes to the plasma membrane may allow macrophages to crawl over selectin-bearing substrates or other cells.

Specifications & PurityAnimal Free, Carrier Free, Azide Free, ≥90%(SDS-PAGE)
Endotoxin Concentration<1.0 EU/μg
Expression SystemHEK293
Amino Acids22-319 aa
SequenceNDCPHKKSATLLPSFTVTPTVTESTGTTSHRTTKSHKTTTHRTTTTGTTSHGPTTATHNPTTTSHGNVTVHPTSNSTATSQGPSTATHSPATTSHGNATVHPTSNSTATSPGFTSSAHPEPPPPSPSPSPTSKETIGDYTWTNGSQPCVHLQAQIQIRVMYTTQGGGEAWGISVLNPNKTKVQGSCEGAHPHLLLSFPYGHLSFGFMQDLQQKVVYLSYMAVEYNVSFPHAAQWTFSAQNASLRDLQAPLGQSFS
Protein TagC-His
Predicted molecular weight32.4 kDa
SDS-PAGE72.9-125.0 kDa, under reducing conditions; 72.9-125.0 kDa, under non-reducing conditions

Images

Recombinant Human CD68 Protein (rp175904) - SDS-PAGE
3 μg/lane of Recombinant Human CD68 Protein was resolved with SDS-PAGE under reducing (R) and non-reducing (N) conditions and visualized by Coomassie® Blue staining, showing a band at 72.9-125.0 kDa under reducing conditions and 72.9-125.0 kDa under non-reducing conditions.

Product Specifications

FormLyophilized
ReconstitutionWe recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute at 0.5 mg/mL in sterile distilled water. Stock solutions should be apportioned into working aliquots and stored at ≤ -20 °C. Further dilu
Storage TempStore at -20°C,Avoid repeated freezing and thawing
Shipped InIce chest + Ice pads
Stability And StorageStore at -20°C for 1 year. Avoid freeze / thaw cycle.

Certificates

Certificate of Analysis(COA)

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4 results found

Lot NumberCertificate TypeDateItem
ZJ24F0303309Certificate of AnalysisMar 22, 2024 rp175904
ZJ24F0303310Certificate of AnalysisMar 22, 2024 rp175904
ZJ24F0303311Certificate of AnalysisMar 22, 2024 rp175904
ZJ24R0300322Certificate of AnalysisMar 08, 2024 rp175904

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