Bioactivity: When Recombinant Human CEACAM‑3/CD66d is immobilized at 2 µg/mL (100 µL/well), the concentration of Recombinant Human CEACAM-7 that produces 50% of the optimal binding response is 0.6-3.6 μg/mL.
Endotoxin Concentration: <1.0 EU/μg
Item Number
rp144254
Grouped product items
SKU
Size
Availability
Price
Qty
rp144254-10μg
10μg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$139.90
rp144254-50μg
50μg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$469.90
rp144254-100μg
100μg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$759.90
rp144254-1mg
1mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
Purity ≥95% (SDS-PAGE) Endotoxin level <1.0 EU/μg Function Major granulocyte receptor mediating recognition and efficient opsonin-independent phagocytosis of CEACAM-binding microorganisms, including Neissiria, Moxarella and Haemophilus species, thus playing an important role in the clearance of pathogens by the innate immune system. Responsible for RAC1 stimulation in the course of pathogen phagocytosis.
When Recombinant Human CEACAM‑3/CD66d is immobilized at 2 µg/mL (100 µL/well), the concentration of Recombinant Human CEACAM-7 that produces 50% of the optimal binding response is 0.6-3.6 μg/mL.
15 - 20 kDa, under reducing conditions; 15 - 20 kDa, under non-reducing conditions.
Images
Recombinant Human CEACAM-3/CD66d Protein (rp144254) - Protein Bioactivity Immobilized Recombinant Human CEACAM-3/CD66d Protein (rp144254) at 2.0 μg/mL, the concentration of Recombinant Human CEACAM-7 that produces 50% of the optimal binding response is 2.2 μg/mL.
Recombinant Human CEACAM-3/CD66d Protein (rp144254) - SDS-PAGE 3 μg/lane of Recombinant Human CEACAM-3/CD66d Protein was resolved with SDS-PAGE under reducing (R) and non-reducing (N) conditions and visualized by Coomassie® Blue staining, showing a band at 15 - 20 kDa.
Product Specifications
Form
Lyophilized
Reconstitution
Reconstitute in sterile water to a concentration of 0.1-0.5 mg/ml.
Storage Temp
Store at -20°C,Avoid repeated freezing and thawing
Shipped In
Wet ice
Stability And Storage
Store at -20~-80℃ for more than 1 year. Upon delivery aliquot. Avoid freeze/thaw cycle.
1.Khan, W N WN and 5 more authors.. (1992) Identification of three new genes and estimation of the size of the carcinoembryonic antigen family.. Genomics, [PMID:1427854]
2.Kuroki, M M and 6 more authors.. (1991) Molecular cloning of nonspecific cross-reacting antigens in human granulocytes.. The Journal of biological chemistry, (25):[PMID:2050678]
3.Nagel, G G and 5 more authors.. (1993) Genomic organization, splice variants and expression of CGM1, a CD66-related member of the carcinoembryonic antigen gene family.. European journal of biochemistry, (15):[PMID:8508798]
4.Streichert, T T and 5 more authors.. (2001) The microbial receptor CEACAM3 is linked to the calprotectin complex in granulocytes.. Biochemical and biophysical research communications, (23):[PMID:11708798]
5.McCaw, Shannon E SE, Schneider, Jutta J, Liao, Edward H EH, Zimmermann, Wolfgang W and Gray-Owen, Scott D SD.. (2003) Immunoreceptor tyrosine-based activation motif phosphorylation during engulfment of Neisseria gonorrhoeae by the neutrophil-restricted CEACAM3 (CD66d) receptor.. Molecular microbiology, [PMID:12864848]
6.Schmitter, Tim T, Agerer, Franziska F, Peterson, Lisa L, Munzner, Petra P and Hauck, Christof R CR.. (2004) Granulocyte CEACAM3 is a phagocytic receptor of the innate immune system that mediates recognition and elimination of human-specific pathogens.. The Journal of experimental medicine, (5):[PMID:14707113]
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