Recombinant Human CXADR Protein

Features and benefits
  • Expression System: HEK293
  • Protein Tag: C-His
  • Bioactivity: Testing in progress
  • Endotoxin Concentration: <1.0 EU/μg
Item Number
rp183611
Grouped product items
SKUSizeAvailabilityPrice Qty
rp183611-10μg (Trial Size)
Apply for free trial size(?)
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10μg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$69.90
rp183611-50μg
50μg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$199.90
rp183611-100μg
100μg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$299.90
rp183611-1mg
1mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$2,599.90

Animal Free, ≥95% (SDS-PAGE), 293F cell, C-His tag, 1-237 aa

Basic Description

Product NameRecombinant Human CXADR Protein
SynonymsCAR4/6 | coxsackie virus and adenovirus receptor | coxsackie virus B receptor | coxsackievirus and adenovirus receptor | CVB3 binding protein | CVB3 BP | CVB3-binding protein | CXADR | HCAR | HCVADR | CAR10Coxsackievirus B-adenovirus receptor
GradeAnimal Free, Carrier Free
Product Description

Protein Function:
CXADR (coxsackie virus and adenovirus receptor), also known as CAR, is a type I transmembrane glycoprotein belonging to the CTX family of the Ig superfamily, and is essential for normal cardiac development in the mouse. Proposed as a homophilic cell adhesion molecule, CXADR is a component of the epithelial apical junction complex that is essential for the tight junction integrity, and probably involved in transepithelial migration of polymorphonuclear leukocytes (PMN). Mature mouse CXADR structrually comprises a 218 aa extracellular domain (ECD) with a V-type (D1) and a C2-type (D2) Ig-like domain, a 21 aa transmembrane segment and a 17 aa intracellular domain, among which,D1 is thought to be responsible for homodimer formation in trans within tight junctions. The ECD of mouse CXADR shares 97%, 9% sequence identity with the corresponding regions of rat, human CXADR.

Specifications & PurityAnimal Free, Carrier Free, ≥95%(SDS-PAGE)
BioactivityTesting in progress
Endotoxin Concentration<1.0 EU/μg
Expression SystemHEK293
Amino Acids1-237 aa
SequenceMALLLCFVLLCGVVDFARSLSITTPEEMIEKAKGETAYLPCKFTLSPEDQGPLDIEWLISPADNQKVDQVIILYSGDKIYDDYYPDLKGRVHFTSNDLKSGDASINVTNLQLSDIGTYQCKVKKAPGVANKKIHLVVLVKPSGARCYVDGSEEIGSDFKIKCEPKEGSLPLQYEWQKLSDSQKMPTSWLAEMTSSVISVKNASSEYSGTYSCTVRNRVGSDQCLLRLNVVPPSNKAGHHHHHH
Protein TagC-His
Predicted molecular weight24.8 kDa
SDS-PAGE29.0-34.0 kDa, under reducing conditions; 24.0-30.0 kDa, under non-reducing conditions

Images

Recombinant Human CXADR Protein (rp183611) - SDS-PAGE
3 μg/lane of Recombinant Human CXADR Protein was resolved with SDS-PAGE under reducing (R) and non-reducing (N) conditions and visualized by Coomassie® Blue staining, showing a band at 29.0-34.0 kDa under reducing conditions and 24.0-30.0 kDa under non-reducing conditions.

Product Specifications

ReconstitutionWe recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute at 0.5 mg/mL in sterile distilled water. Stock solutions should be apportioned into working aliquots and stored at ≤ -20 °C. Further dilu
Storage TempStore at -20°C,Avoid repeated freezing and thawing
Shipped InIce chest + Ice pads
Stability And StorageStore at -20°C for 1 year. Avoid freeze / thaw cycle.

Certificates

Certificate of Analysis(COA)

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4 results found

Lot NumberCertificate TypeDateItem
ZJ24F0708021Certificate of AnalysisJul 12, 2024 rp183611
ZJ24F0708020Certificate of AnalysisJul 12, 2024 rp183611
ZJ24F0708019Certificate of AnalysisJul 12, 2024 rp183611
ZJ24R0600710Certificate of AnalysisJun 23, 2024 rp183611

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