Recombinant Human CXCL10/IP-10 Protein

Features and benefits
  • Expression System: E. coli
  • Protein Tag: No tag
  • Bioactivity: Immobilized Recombinant Human CXCL10/IP-10 Protein (rp170434) at 1.0 μg/mL can bind Eldelumab (anti-CXCL10) (Ab170882) with the EC50 of 268.7 ng/mL.
  • Endotoxin Concentration: <1.0 EU/μg
Item Number
rp170434
Grouped product items
SKUSizeAvailabilityPrice Qty
rp170434-10μg (Trial Size)
Apply for free trial size(?)
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10μg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$139.90
rp170434-50μg
50μg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$399.90
rp170434-100μg
100μg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$599.90
rp170434-1mg
1mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$2,599.90

Animal Free, ≥90% (SDS-PAGE), Active, E. coli, No tag, 22-98 aa

Basic Description

Product NameRecombinant Human CXCL10/IP-10 Protein
Synonymschemokine (C-X-C motif) ligand 10 | CRG2 | CRG-2 | CXCL10 | gIP-10 | IFI10 | INP10 | IP-10 | mob-1 | SCYB10 | C7
GradeActiBioPure™, Bioactive, Carrier Free
Product Description

Protein Function:
(C-X-C motif) ligand (CXCL)10 (CXCL10) belongs to the ELR(-) CXC subfamily chemokine. CXCL10/IP-10 exerts its function through binding to chemokine (C-X-C motif) receptor 3 (CXCR3), a seven trans-membrane receptor coupled to G proteins. CXCL10/IP-10 and its receptor, CXCR3, appear to contribute to the pathogenesis of many autoimmune diseases, organ specific (such as type 1 diabetes, autoimmune thyroiditis, Graves' disease and ophthalmopathy), or systemic (such as rheumatoid arthritis, psoriatic arthritis, systemic lupus erythematosus, mixed cryoglobulinemia, Sjögren syndrome, or systemic sclerosis). CXCL10/IP-10 is secreted by several cell types including endothelial cells, fibroblasts, keratinocytes, thyrocytes, preadipocytes, etc. Determination of high level of CXCL10/IP-10 in peripheral fluids is therefore a marker of host immune response.

Specifications & PurityActiBioPure™, Bioactive, Carrier Free, ≥90%(SDS-PAGE)
BioactivityImmobilized Recombinant Human CXCL10/IP-10 Protein (rp170434) at 1.0 μg/mL can bind Eldelumab (anti-CXCL10) (Ab170882) with the EC50 of 268.7 ng/mL.
Endotoxin Concentration<1.0 EU/μg
Expression SystemE. coli
Amino Acids22-98 aa
SequenceVPLSRTVRCTCISISNQPVNPRSLEKLEIIPASQFCPRVEIIATMKKKGEKRCLNPESKAIKNLLKAVSKERSKRSP
Protein TagNo tag
Predicted molecular weight20.8 kDa
SDS-PAGE11.3 kDa, under reducing conditions

Images

Recombinant Human CXCL10/IP-10 Protein (rp170434) - ELISA
Immobilized Recombinant Human CXCL10/IP-10 Protein (rp170434) at 1.0 μg/mL can bind Eldelumab (anti-CXCL10) (Ab170882) with the EC₅₀of 268.7 ng/mL.


Recombinant Human CXCL10/IP-10 Protein (rp170434) - SDS-PAGE
1 μg/lane of Recombinant Human CXCL10/IP-10 Protein was resolved with SDS-PAGE under reducing (R) conditions and visualized by Coomassie® Blue staining, showing a band at 11.3 kDa under reducing conditions.

Product Specifications

ReconstitutionWe recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute at 0.5 mg/mL in sterile distilled water. Stock solutions should be apportioned into working aliquots and stored at ≤ -20 °C. Further dilu
Storage TempStore at -20°C,Avoid repeated freezing and thawing
Shipped InIce chest + Ice pads
Stability And StorageStore at -20°C for 1 year. Avoid freeze / thaw cycle.

Certificates

Certificate of Analysis(COA)

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3 results found

Lot NumberCertificate TypeDateItem
ZJ24F0708056Certificate of AnalysisJul 12, 2024 rp170434
ZJ24F0708055Certificate of AnalysisJul 12, 2024 rp170434
ZJ24F0708054Certificate of AnalysisJul 12, 2024 rp170434

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