Recombinant Human Cyclophilin A Protein, >95% (SDS-PAGE), high purity

Features and benefits
  • Expression System: E. coli
  • Protein Tag: N-His & SUMO
  • Endotoxin Concentration: <1.0 EU/μg
Item Number
rp183694
Grouped product items
SKUSizeAvailabilityPrice Qty
rp183694-10μg (Trial Size)
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10μg
Available within 8-12 weeks(?)
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$59.90
rp183694-100μg
100μg
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$329.90
rp183694-1mg
1mg
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$2,299.90

Carrier Free, >95% (SDS-PAGE), E. coli, N-His-Sumo tag, 2-165 aa

Basic Description

Product NameRecombinant Human Cyclophilin A Protein, >95% (SDS-PAGE), high purity
SynonymsCyclophilin A | Cyclosporin A-binding protein | CYPA | CYPAMGC12404 | CYPH | EC 5.2.1.8 | MGC117158 | MGC23397 | peptidyl-prolyl cis-trans isomerase A | peptidylprolyl isomerase A (cyclophilin A) | PPIA | PPIase A | Rotamase A | Rotamase | T cell cyclophi
GradeAzide Free, Carrier Free
Product Description

Purity: >95%, by SDS-PAGE visualized with Coomassie® Blue Staining.
Description:
Cyclophilin A, also called Peptidyl-prolyl Isomerase A, PPIA, CYPA, and CYPH, was originally characterized for its ability to catalyze the transition between cis- and trans-proline residues critical for proper folding of proteins. Cyclophilin is also incorporated into many viruses, including HIV-1, where it has been speculated to be involved in functions such as viral assembly and infectivity. The immunosuppressive activity of cyclosporins has been correlated with their ability to form complexes with cyclophilins that inhibit calcineurin phosphatase activity and prevent incorporation of cyclophilin into viral particles. The cyclosporin/cyclophilin complex selectively binds and inactivates calcineurin, making it a useful inhibitor for studying calcineurin activity.

Specifications & PurityCarrier Free, Azide Free, ≥95%(SDS-PAGE)
Purity>95% (SDS-PAGE)
Endotoxin Concentration<1.0 EU/μg
Expression SystemE. coli
Amino Acids2-165 aa
SequenceMGSSHHHHHHSSGLVPRGSHMASMSDSEVNQEAKPEVKPEVKPETHINLKVSDGSSEIFFKIKKTTPLRRLMEAFAKRQGKEMDSLRFLYDGIRIQADQTPEDLDMEDNDIIEAHREQIGGVNPTVFFDIAVDGEPLGRVSFELFADKVPKTAENFRALSTGEKGFGYKGSCFHRIIPGFMCQGGDFTRHNGTGGKSIYGEKFEDENFILKHTGPGILSMANAGPNTNGSQFFICTAKTEWLDGKHVVFGKVKEGMNIVEAMERFGSRNGKTSKKITIADCGQLE
Protein TagN-His & SUMO
Predicted molecular weight31.6 kDa
SDS-PAGE32.6 kDa, under reducing conditions; 32.6 kDa, under non-reducing conditions

Images

Recombinant Human Cyclophilin A Protein (rp183694) - SDS-PAGE
3 μg/lane of Recombinant Human Cyclophilin A Protein was resolved with SDS-PAGE under reducing (R) and non-reducing (N) conditions and visualized by Coomassie® Blue staining, showing a band at 32.6 kDa.

Product Specifications

FormLyophilized
ReconstitutionWe recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute at 1.0 mg/mL in sterile distilled water. Stock solutions should be apportioned into working aliquots and stored at ≤ -20 °C. Further dilu
Storage TempStore at -20°C,Avoid repeated freezing and thawing
Shipped InIce chest + Ice pads
Stability And StorageStore at -20°C stable up to 1 year. Avoid freeze / thaw cycle.

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Solution Calculators