Purity ≥95% (SDS-PAGE) Endotoxin level <0.1 EU/μg Function Binds to the receptor tyrosine kinases EPHB1 and EPHA1. Binds to, and induce the collapse of, commissural axons/growth cones in vitro. May play a role in constraining the orientation of longitudinally projecting axons.
1.Davis, S S and 7 more authors.. (1994) Ligands for EPH-related receptor tyrosine kinases that require membrane attachment or clustering for activity.. Science (New York, N.Y.), (4):[PMID:7973638]
2.Beckmann, M P MP and 9 more authors.. (1994) Molecular characterization of a family of ligands for eph-related tyrosine kinase receptors.. The EMBO journal, (15):[PMID:8070404]
3.Brückner, K K and 5 more authors.. (1999) EphrinB ligands recruit GRIP family PDZ adaptor proteins into raft membrane microdomains.. Neuron, [PMID:10197531]
4.Wieland, Ilse I and 7 more authors.. (2004) Mutations of the ephrin-B1 gene cause craniofrontonasal syndrome.. American journal of human genetics, [PMID:15124102]
5.Twigg, Stephen R F SR and 7 more authors.. (2004) Mutations of ephrin-B1 (EFNB1), a marker of tissue boundary formation, cause craniofrontonasal syndrome.. Proceedings of the National Academy of Sciences of the United States of America, (8):[PMID:15166289]
6.Zhang, Zemin Z and Henzel, William J WJ.. (2004) Signal peptide prediction based on analysis of experimentally verified cleavage sites.. Protein science : a publication of the Protein Society, [PMID:15340161]
7.Ross, Mark T MT and 281 more authors.. (2005) The DNA sequence of the human X chromosome.. Nature, (17):[PMID:15772651]
8.Wieland, Ilse I and 14 more authors.. (2005) Twenty-six novel EFNB1 mutations in familial and sporadic craniofrontonasal syndrome (CFNS).. Human mutation, [PMID:15959873]
9.Tomita, Taisuke T, Tanaka, Sayaka S, Morohashi, Yuichi Y and Iwatsubo, Takeshi T.. (2006) Presenilin-dependent intramembrane cleavage of ephrin-B1.. Molecular neurodegeneration, (12):[PMID:16930449]
Solution Calculators
Molarity Calculator
Determine the necessary mass, volume, or concentration for preparing a solution.
Dilution Calculator
Determine the dilution needed to prepare a stock solution.