Bioactivity: Measured in a cell proliferation assay using MCF‑7 human breast cancer cells in the presence of 2 μg/mL of heparin sodium. The ED50 for this effect is typically <21ng/mL.
Endotoxin Concentration: <0.1 EU/μg
Item Number
rp145913
Grouped product items
SKU
Size
Availability
Price
Qty
rp145913-10μg
10μg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$139.90
rp145913-25μg
25μg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$269.90
rp145913-100μg
100μg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$599.90
rp145913-1mg
1mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
Measured in a cell proliferation assay using MCF‑7 human breast cancer cells in the presence of 2 μg/mL of heparin sodium. The ED50 for this effect is typically <21ng/mL.
19.8 kDa, under reducing conditions; 19.8 kDa, under non-reducing conditions.
Images
Recombinant Human FGF10 Protein (rp145913)-Protein Bioactivity Measured in a cell proliferation assay using MCF‑7 human breast cancer cells in the presence of 2 μg/mL of heparin sodium. The ED₅₀ for this effect is typically <21ng/mL.
Recombinant Human FGF10 Protein (rp145913)-SDS-PAGE 3μg/lane of Recombinant Human FGF10 Protein was resolved with SDS-PAGE under reducing (R) and non-reducing (N) conditions and visualized by Coomassie® Blue staining, showing a single band at 19.8 kDa.
Product Specifications
Form
Lyophilized
Reconstitution
Centrifuge first and redissolve with deionized water to proposal concentration.
Storage Temp
Store at -20°C
Shipped In
Ice chest + Ice pads
Stability And Storage
Shipped at 4°C. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
Certificates
Certificate of Analysis(COA)
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1.Gerhard DS, Wagner L, Feingold EA, Shenmen CM, Grouse LH, Schuler G, Klein SL, Old S, Rasooly R, Good P et al.. (2004) The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).. Genome Res, 14 (10B):(2121-7). [PMID:15489334][10.1021/op500134e]
2.Yeh BK, Igarashi M, Eliseenkova AV, Plotnikov AN, Sher I, Ron D, Aaronson SA, Mohammadi M. (2003) Structural basis by which alternative splicing confers specificity in fibroblast growth factor receptors.. Proc Natl Acad Sci USA, 100 (5):(2266-71). [PMID:12591959][10.1021/op500134e]
3.Emoto, H H and 10 more authors.. (1997) Structure and expression of human fibroblast growth factor-10.. The Journal of biological chemistry, (12):[PMID:9287324]
4.Entesarian, Miriam M and 12 more authors.. (2005) Mutations in the gene encoding fibroblast growth factor 10 are associated with aplasia of lacrimal and salivary glands.. Nature genetics, [PMID:15654336]
5.Beer, Hans-Dietmar HD and 6 more authors.. (2005) The fibroblast growth factor binding protein is a novel interaction partner of FGF-7, FGF-10 and FGF-22 and regulates FGF activity: implications for epithelial repair.. Oncogene, (11):[PMID:15806171]
6.Rohmann, Edyta E and 21 more authors.. (2006) Mutations in different components of FGF signaling in LADD syndrome.. Nature genetics, [PMID:16501574]
7.Zhang, Xiuqin X and 5 more authors.. (2006) Receptor specificity of the fibroblast growth factor family. The complete mammalian FGF family.. The Journal of biological chemistry, (9):[PMID:16597617]
8.Milunsky, J M JM, Zhao, G G, Maher, T A TA, Colby, R R and Everman, D B DB.. (2006) LADD syndrome is caused by FGF10 mutations.. Clinical genetics, [PMID:16630169]
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