Recombinant Human FGFR4 protein, >95%(SDS-PAGE), high purity

Features and benefits
  • Expression System: HEK293
  • Accession #: P22455
  • Protein Tag: C-Fc & His
  • Bioactivity: Measured by its ability to inhibit FGF-acidic dependent proliferation of Balb/c 3T3 mouse fibroblasts. The ED50 for this effect is typically 0.03-0.12 ng/mL.
  • Endotoxin Concentration: <0.1 EU/μg
Item Number
rp146021
Grouped product items
SKUSizeAvailabilityPrice Qty
rp146021-10μg
10μg
In stock
$69.90
rp146021-50μg
50μg
In stock
$309.90
rp146021-100μg
100μg
In stock
$599.90
rp146021-1mg
1mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$4,999.90

Animal Free , >95%(SDS-PAGE), Active, 293F, Fc&His tag, 22-376 aa

Basic Description

Product NameRecombinant Human FGFR4 protein, >95%(SDS-PAGE), high purity
SynonymsCD 334 | CD334 | CD334 antigen | fc13h 10 | fc13h10 | Fgfr 4 | FGFR-4 | Fgfr4 | FGFR4_HUMAN | Fibroblast growth factor receptor 4 | Hydroxyaryl protein kinase | JTK 2 | JTK2 | MGC20292 | Protein tyrosine kinase | TKF | Tyrosine kinase related to fibroblas
GradeActiBioPure™, Animal Free, Azide Free, Bioactive, Carrier Free
Product Description

Purity

>95% SDS-PAGE


Function

Receptor for acidic fibroblast growth factor. Does not bind to basic fibroblast growth factor. Binds FGF19.


Post-translational

Glycosylated. Phosphorylated on tyrosine residue (By similarity). Phosphorylation requires the presence of a functional (phosphorylated) FGFR1 and not necessarily by means of FGFR heterodimerization.

Specifications & PurityActiBioPure™, Bioactive, Animal Free, Carrier Free, Azide Free, ≥95%(SDS-PAGE)
Purity>95%(SDS-PAGE)
BioactivityMeasured by its ability to inhibit FGF-acidic dependent proliferation of Balb/c 3T3 mouse fibroblasts. The ED50 for this effect is typically 0.03-0.12 ng/mL.
Endotoxin Concentration<0.1 EU/μg
Expression SystemHEK293
SpeciesHuman
Amino Acids22-376 aa
SequenceLEASEEVELEPCLAPSLEQQEQELTVALGQPVRLCCGRAERGGHWYKEGSRLAPAGRVRGWRGRLEIASFLPEDAGRYLCLARGSMIVLQNLTLITGDSLTSSNDDEDPKSHRDPSNRHSYPQQAPYWTHPQRMEKKLHAVPAGNTVKFRCPAAGNPTPTIRWLKDGQAFHGENRIGGIRLRHQHWSLVMESVVPSDRGTYTCLVENAVGSIRYNYLLDVLERSPHRPILQAGLPANTTAVVGSDVELLCKVYSD
Protein TagC-Fc & His
Accession #P22455
Predicted molecular weight66 kDa
SDS-PAGE91.8 kDa, under reducing conditions; 210.5 kDa, under non-reducing conditions.

Images

Recombinant Human FGFR4 protein (rp146021) - Protein Bioactivity
Measured by its ability to inhibit FGF-acidic dependent proliferation of Balb/c 3T3 mouse fibroblasts. The ED₅₀ for this effect is typically 0.03 - 0.12 ng/mL.

Recombinant Human FGFR4 protein (rp146021) - SDS-PAGE
3 μg/lane of Recombinant Human FGFR4 protein was resolved with SDS-PAGE under reducing (R) and non-reducing (N) conditions and visualized by Coomassie® Blue staining, showing a band at 91.8 kDa under reducing conditions and 210.5 kDa under non-reducing conditions.

Product Specifications

FormLyophilized
ReconstitutionReconstitute in water to a concentration of 0.1-0.5 mg/ml.
Storage TempStore at -20°C,Avoid repeated freezing and thawing
Shipped InIce chest + Ice pads
Stability And StorageStore at -20~-80℃ for more than 1 year

Certificates

Certificate of Analysis(COA)

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3 results found

Lot NumberCertificate TypeDateItem
ZJ23F1202259Certificate of AnalysisDec 28, 2023 rp146021
ZJ23F1202258Certificate of AnalysisDec 28, 2023 rp146021
ZJ23F1202257Certificate of AnalysisDec 28, 2023 rp146021

Related Documents

References

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