| SKU | Size | Availability | Price | Qty |
|---|---|---|---|---|
| rp146027-10μg | 10μg | In stock | $539.90 | |
| rp146027-50μg | 50μg | In stock | $1,209.90 | |
| rp146027-100μg | 100μg | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $1,939.90 | |
| rp146027-1mg | 1mg | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $16,499.90 |
Animal Free, >95% (SDS-PAGE), Active, HEK293, C-Fc tag, 23-312 aa
| Product Name | Recombinant Human FGL1 Protein, >95% (SDS-PAGE), high purity |
|---|---|
| Synonyms | FGL1 | fibrinogen-like 1 | fibrinogen-like protein 1 | Fibrinogen-like-protein 1 | FREP1 | Hepassocin | hepatocellular carcinoma-related sequence | Hepatocyte-derived fibrinogen-related protein 1 | HFREP-1 | HFREP1MGC12455 | HP-041 | LFIRE1 | LFIRE-1 | Li |
| Grade | ActiBioPure™, Animal Free, Azide Free, Bioactive, Carrier Free |
| Product Description | Purity |
| Specifications & Purity | ActiBioPure™, Bioactive, Animal Free, Carrier Free, Azide Free, ≥95%(SDS-PAGE) |
| Purity | >95% (SDS-PAGE) |
| Bioactivity | 1. Immobilized Recombinant Human LAG-3 Protein at 1 μg/mL can bind biotinylated Recombinant Human FGL1 Protein (rp146027).2. Loaded Human LAG-3 Protein on AMC Biosensor, can bind Recombinant Human FGL1 Protein (rp146027) with an affinity constant of 56.8 |
| Endotoxin Concentration | <1.0 EU/μg |
| Expression System | HEK293 |
| Species | Human |
| Amino Acids | 23-312 aa |
| Sequence | LEDCAQEQMRLRAQVRLLETRVKQQQVKIKQLLQENEVQFLDKGDENTVIDLGSKRQYADCSEIFNDGYKLSGFYKIKPLQSPAEFSVYCDMSDGGGWTVIQRRSDGSENFNRGWKDYENGFGNFVQKHGEYWLGNKNLHFLTTQEDYTLKIDLADFEKNSRYAQYKNFKVGDEKNFYELNIGEYSGTAGDSLAGNFHPEVQWWASHQRMKFSTWDRDHDNYEGNCAEEDQSGWWFNRCHSANLNGVYYSGPYTAKTDNGIVWYTWHGWWYSLKSVVMKIRPNDFIPNVIADDDDKEPKSSDKTHTCPPCPAPELLGGPSVFLFPPKPKDTLMISRTPEVTCVVVDVSHEDPEVKFNWYVDGVEVHNAKTKPREEQYNSTYRVVSVLTVLHQDWLNGKEYKCKVSNKALPAPIEKTISKAKGQPREPQVYTLPPSRDELTKNQVSLTCLVKGFYPSDIAVEWESNGQPENNYKTTPPVLDSDGSFFLYSKLTVDKSRWQQGNVFSCSVMHEALHNHYTQKSLSLSPGK |
| Protein Tag | C-Fc |
| Accession # | Q08830 |
| Predicted molecular weight | 60.7 kDa |
| SDS-PAGE | 61.3 kDa, under reducing conditions; 136.3 kDa, under non-reducing conditions. |
Recombinant Human FGL1 Protein (rp146027) - Protein Bioactivity
Immobilized Recombinant Human LAG-3 Protein at 1 μg/mL can bind biotinylated Recombinant Human FGL1 Protein (rp146027).
Recombinant Human FGL1 Protein (rp146027) - BLI Assay
Loaded Human LAG-3 Protein on AMC Biosensor, can bind Recombinant Human FGL1 Protein (rp146027) with an affinity constant of 56.8 nM as determined in BLI assay.
Recombinant Human FGL1 Protein (rp146027) - SDS-PAGE
3 μg/lane of Recombinant Human FGL1 Protein was resolved with SDS-PAGE under reducing (R) and non-reducing (N) conditions and visualized by Coomassie® Blue staining, showing the band at 61.3 kDa under reducing conditions and 136.3 kDa under non-reducing conditions.
| Form | Lyophilized |
|---|---|
| Reconstitution | It is recommended that sterile water be added to the vial to prepare a stock solution of 0.25mg/mL. |
| Storage Temp | Store at -20°C,Avoid repeated freezing and thawing |
| Shipped In | Ice chest + Ice pads |
| Stability And Storage | Samples are stable for twelve months from date of receipt at -20℃ to -80℃. Upon delivery aliquot. Avoid freeze/thaw cycle. |
Enter Lot Number to search for COA:
Find and download the COA for your product by matching the lot number on the packaging.
| Lot Number | Certificate Type | Date | Item |
|---|---|---|---|
 ZJ23F1101858 | Certificate of Analysis | Dec 01, 2023 | rp146027 |
| ZJ23F1101857 | Certificate of Analysis | Dec 01, 2023 | rp146027 |
| 1. Yamamoto, T T and 5 more authors.. (1993) Molecular cloning and initial characterization of a novel fibrinogen-related gene, HFREP-1.. Biochemical and biophysical research communications, (15): [PMID:8390249] |
| 2. Hara, H H and 7 more authors.. (2001) Molecular cloning and functional expression analysis of a cDNA for human hepassocin, a liver-specific protein with hepatocyte mitogenic activity.. Biochimica et biophysica acta, (30): [PMID:11470158] |
| 3. Nusbaum, Chad C and 75 more authors.. (2006) DNA sequence and analysis of human chromosome 8.. Nature, (19): [PMID:16421571] |
| 4. Liu, Zhilin Z and Ukomadu, Chinweike C.. (2008) Fibrinogen-like protein 1, a hepatocyte derived protein is an acute phase reactant.. Biochemical and biophysical research communications, (25): [PMID:18039467] |
| 5. Wang, Jun and 20 more authors.. (2019) Fibrinogen-like Protein 1 Is a Major Immune Inhibitory Ligand of LAG-3.. Cell, (10): [PMID:30580966] |
