Recombinant Human Flt-3 Ligand/FLT3L GMP Protein

Features and benefits
  • Expression System: E. coli
  • Protein Tag: No tag
  • Bioactivity: Measured in a cell proliferation assay using OCI-AML5 acute myeloid leukemia cells. The ED50 for this effect is 0.200-2.00 ng/mL. The specific activity of Recombinant Human Flt-3 Ligand/FLT3L is >5.00 x 10^5 units/mg, which is calibrated against the human
  • Endotoxin Concentration: <0.1 EU/μg
Item Number
rp163960-GMP
Grouped product items
SKUSizeAvailabilityPrice Qty
rp163960-GMP-50μg
50μg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$1,279.90
rp163960-GMP-1mg
1mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$10,239.90

GMP, ≥97% (SDS-PAGE&SEC-HPLC), Active, E.coli, No tag, 27-181 aa

Basic Description

Product NameRecombinant Human Flt-3 Ligand/FLT3L GMP Protein
Synonymsfms-like Tyrosine Kinase 3 Ligand | FL | FLG3L | Flt3 ligand | Flt-3 Ligand | Flt3L | FLT3LG | fms-related tyrosine kinase 3 ligand | SL cytokine | IMD125
GradeActiBioPure™, Animal Free, Bioactive, Carrier Free, GMP, High Performance
Specifications & PurityAnimal Free, Carrier Free, GMP, Bioactive, ActiBioPure™, High performance, ≥97%(SDS-PAGE&SEC-HPLC)
Biochemical and Physiological Mechanisms Stimulates the proliferation of early hematopoietic cells by activating FLT3. Synergizes well with a number of other colony stimulating factors and interleukins.
BioactivityMeasured in a cell proliferation assay using OCI-AML5 acute myeloid leukemia cells. The ED50 for this effect is 0.200-2.00 ng/mL. The specific activity of Recombinant Human Flt-3 Ligand/FLT3L is >5.00 x 10^5 units/mg, which is calibrated against the human
Endotoxin Concentration<0.1 EU/μg
Expression SystemE. coli
Amino Acids27-181 aa
SequenceMTQDCSFQHSPISSDFAVKIRELSDYLLQDYPVTVASNLQDEELCGGLWRLVLAQRWMERLKTVAGSKMQGLLERVNTEIHFVTKCAFQPPPSCLRFVQTNISRLLQETSEQLVALKPWITRQNFSRCLELQCQPDSSTLPPPWSPRPLEATAPTA
Protein TagNo tag
N-terminal SequenceMet-Thr27-Gln-Asp-(Cys)-Ser-Phe-Gln-His-Ser & Thr27-Gln-Asp-(Cys)-Ser-Phe-Gln-His-Ser-Pro
Predicted molecular weight18 kDa
SDS-PAGE17 kDa under reducing conditions.

Associated Targets(Human)

FLT3LG Tbio Fms-related tyrosine kinase 3 ligand (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

Product Specifications

ReconstitutionReconstitute at 500 μg/mL in PBS.
Storage TempStore at -20°C,Avoid repeated freezing and thawing
Shipped InIce chest + Ice pads
Stability And StorageA minimum of 12 months when stored at ≤ -20 ℃ as supplied. 1 month, 2 to 8 ℃ under sterile conditions after reconstitution. 3 months, ≤ -20 ℃ under sterile conditions after reconstitution. Upon delivery aliquot. Avoid freeze/thaw cycle.

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