| SKU | Size | Availability | Price | Qty |
|---|---|---|---|---|
| rp146266-10μg (Trial Size) Apply for free trial size（?） Every year, as a valued customer, you have the exclusive opportunity to explore and enjoy three different trial products of your choice, absolutely free! | 10μg | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $79.90 | |
| rp146266-50μg | 50μg | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $199.90 | |
| rp146266-100μg | 100μg | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $289.90 | |
| rp146266-1mg | 1mg | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $1,999.90 |
Animal Free, >98% (SDS-PAGE&HPLC), Active, E.coli, No tag, 2-250 aa
| Product Name | Recombinant Human Galectin 3 Protein, >98% (SDS-PAGE&HPLC), high purity |
|---|---|
| Synonyms | AGE-R3; Carbohydrate-binding protein 35; CBP 35,35 kDa lectin; CBP35; GAL3; Gal-3; galactin-3; Galactose-specific lectin 3; Galactoside-binding protein; GALBPCBP35; Galectin3; Galectin-3; GALIG; IgE-binding protein; L29; L31; L-31; Laminin-binding protein |
| Specifications & Purity | ActiBioPure™, Bioactive, Animal Free, Carrier Free, Azide Free, High performance, ≥98%(SDS-PAGE&HPLC) |
| Purity | >98% (SDS-PAGE&HPLC) |
| Species | Human |
| Amino Acids | 2-250 aa |
| Sequence | ADNFSLHDALSGSGNPNPQGWPGAWGNQPAGAGGYPGASYPGAYPGQAPPGAYPGQAPPGAYPGAPGAYPGAPAPGVYPGPPSGPGAYPSSGQPSATGAYPATGPYGAPAGPLIVPYNLPLPGGVVPRMLITILGTVKPNANRIALDFQRGNDVAFHFNPRFNENNRRVIVCNTKLDNNWGREERQSVFPFESGKPFKIQVLVEPDHFKVAVNDAHLLQYNHRVKKLNEISKLGISGDIDLTSASYTMI |
| Protein Tag | No tag |
| Accession # | P17931 |
| Predicted molecular weight | 26.0 kDa |
| SDS-PAGE | 26.0 kDa |
| Grade | ActiBioPure™, Animal Free, Azide Free, Bioactive, Carrier Free, High performance |
Recombinant Human Galectin 3 Protein (rp146266) - Protein Bioactivity
Fully biologically active when compared to standard. The ED₅₀ as determined by its ability to agglutinate human red blood cells is less than 10 μg/mL.
Recombinant Human Galectin 3 Protein (rp146266) - SDS-PAGE
Recombinant Human Galectin 3 Protein was resolved with SDS-PAGE under reducing (R) and non-reducing (N) conditions and visualized by Coomassie® Blue staining, showing a band at 26.0 kDa.
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
|---|
| Form | Lyophilized |
|---|---|
| Reconstitution | We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1 % BSA to a concentration of 0.1-1.0 mg/mL. Stock solutions should be apporti |
| Storage Temp | Store at -20°C,Avoid repeated freezing and thawing |
| Shipped In | Dry ice |
| Stability And Storage | 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 3 months, -20 to -70 °C under sterile conditions after reconstitution. Upon delivery aliquot. Avoid freeze/thaw cycle. |
Enter Lot Number to search for COA:
To view the certificate results,please click on a Lot number.For Lot numbers from past orders,please use our order status section
| Lot Number | Certificate Type | Date | Item |
|---|---|---|---|
 ZJ23F1001360 | Certificate of Analysis | Oct 19, 2023 | rp146266 |
| ZJ23F1001361 | Certificate of Analysis | Oct 19, 2023 | rp146266 |
| ZJ23F1001362 | Certificate of Analysis | Oct 19, 2023 | rp146266 |
| 1. Gerhard DS, Wagner L, Feingold EA, Shenmen CM, Grouse LH, Schuler G, Klein SL, Old S, Rasooly R, Good P et al.. (2004) The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).. Genome Res, 14 (10B): (2121-7). [PMID:15489334] |
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| 7. Gabr M,Rehman AU,Chen HF. (2020) Quinoline-Pyrazole Scaffold as a Novel Ligand of Galectin-3 and Suppressor of TREM2 Signaling.. ACS Med Chem Lett, 11 (9): (1759-1765). [PMID:32944144] |
| 8. Raz, A A and 5 more authors.. (1991) Molecular cloning and chromosomal mapping of a human galactoside-binding protein.. Cancer research, (15): [PMID:2009535] |
| 9. Oda, Y Y, Leffler, H H, Sakakura, Y Y, Kasai, K K and Barondes, S H SH.. (1991) Human breast carcinoma cDNA encoding a galactoside-binding lectin homologous to mouse Mac-2 antigen.. Gene, (15): [PMID:2022338] |
| 10. Robertson, M W MW, Albrandt, K K, Keller, D D and Liu, F T FT.. (1990) Human IgE-binding protein: a soluble lectin exhibiting a highly conserved interspecies sequence and differential recognition of IgE glycoforms.. Biochemistry, (4): [PMID:2261464] |
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| 13. Huflejt, M E ME, Turck, C W CW, Lindstedt, R R, Barondes, S H SH and Leffler, H H.. (1993) L-29, a soluble lactose-binding lectin, is phosphorylated on serine 6 and serine 12 in vivo and by casein kinase I.. The Journal of biological chemistry, (15): [PMID:8253806] |
| 14. Kadrofske, M M MM, Openo, K P KP and Wang, J L JL.. (1998) The human LGALS3 (galectin-3) gene: determination of the gene structure and functional characterization of the promoter.. Archives of biochemistry and biophysics, (1): [PMID:9439577] |
| 15. Sasaki, T T, Brakebusch, C C, Engel, J J and Timpl, R R.. (1998) Mac-2 binding protein is a cell-adhesive protein of the extracellular matrix which self-assembles into ring-like structures and binds beta1 integrins, collagens and fibronectin.. The EMBO journal, (16): [PMID:9501082] |
| 16. Seetharaman, J J and 5 more authors.. (1998) X-ray crystal structure of the human galectin-3 carbohydrate recognition domain at 2.1-A resolution.. The Journal of biological chemistry, (22): [PMID:9582341] |
| 17. Heilig, Roland R and 98 more authors.. (2003) The DNA sequence and analysis of human chromosome 14.. Nature, (6): [PMID:12508121] |
| 18. Fukushi, Jun-ichi J, Makagiansar, Irwan T IT and Stallcup, William B WB.. (2004) NG2 proteoglycan promotes endothelial cell motility and angiogenesis via engagement of galectin-3 and alpha3beta1 integrin.. Molecular biology of the cell, [PMID:15181153] |
| 19. Seidel, Ronald D RD, Zhuang, Tiandi T and Prestegard, James H JH.. (2007) Bound-state residual dipolar couplings for rapidly exchanging ligands of His-tagged proteins.. Journal of the American Chemical Society, (18): [PMID:17385862] |
| 20. Than, Nandor Gabor NG and 24 more authors.. (2009) A primate subfamily of galectins expressed at the maternal-fetal interface that promote immune cell death.. Proceedings of the National Academy of Sciences of the United States of America, (16): [PMID:19497882] |
| 21. Haudek, Kevin C and 5 more authors.. (2010) Dynamics of galectin-3 in the nucleus and cytoplasm.. Biochimica et biophysica acta, [PMID:19616076] |
| 22. Zhou, Houjiang H and 6 more authors.. (2013) Toward a comprehensive characterization of a human cancer cell phosphoproteome.. Journal of proteome research, (4): [PMID:23186163] |
| 23. Escoda-Ferran, Cristina C and 8 more authors.. (2014) Modulation of CD6 function through interaction with Galectin-1 and -3.. FEBS letters, (25): [PMID:24945728] |
| 24. Chauhan, Santosh S and 11 more authors.. (2016) TRIMs and Galectins Globally Cooperate and TRIM16 and Galectin-3 Co-direct Autophagy in Endomembrane Damage Homeostasis.. Developmental cell, (10): [PMID:27693506] |
