Recombinant Human GFR alpha-2/GFRA2 Protein, ≥95% (SDS-PAGE), high purity

Features and benefits
  • Expression System: HEK293
  • Accession #: O00451-1
  • Protein Tag: C-His
  • Bioactivity: Immobilized Recombinant Human Neurturin Protein at 5.0 μg/mL can bind Recombinant Human GFR alpha-2/GFRA2 Protein (rp146403), the EC50 of this effect is 1.99 μg/mL.
  • Endotoxin Concentration: <0.1 EU/μg
Item Number
rp146403
Grouped product items
SKUSizeAvailabilityPrice Qty
rp146403-10μg
10μg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$99.90
rp146403-50μg
50μg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$249.90
rp146403-100μg
100μg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$399.90
rp146403-1mg
1mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$1,999.90

Animal Free, ≥95% (SDS-PAGE), Active, HEK293, C-His tag, 22-441 aa

Basic Description

Product NameRecombinant Human GFR alpha-2/GFRA2 Protein, ≥95% (SDS-PAGE), high purity
SynonymsGDNF family receptor alpha 2; GDNF family receptor alpha-2; GDNF receptor alpha-2; GDNF receptor beta; GDNFR beta; GDNFR-alpha-2; GDNFR-beta; GDNFRB; GFR alpha 2; GFR-alpha-2; GFRA 2; Gfra2; GFRA2_HUMAN; Glial cell line derived neurotrophic factor family
GradeActiBioPure™, Animal Free, Azide Free, Bioactive, Carrier Free
Product Description

Purity

≥95% (SDS-PAGE)

Endotoxin level

<0.1 EU/μg

Function

Receptor for neurturin. Mediates the NRTN-induced autophosphorylation and activation of the RET receptor. Also able to mediate GDNF signaling through the RET tyrosine kinase receptor. Isoform 2: Participates to NRTN-induced 'Ser-727' phosphorylation of STAT3.

Specifications & PurityActiBioPure™, Bioactive, Animal Free, Carrier Free, Azide Free, ≥95%(SDS-PAGE)
Purity≥95% (SDS-PAGE)
BioactivityImmobilized Recombinant Human Neurturin Protein at 5.0 μg/mL can bind Recombinant Human GFR alpha-2/GFRA2 Protein (rp146403), the EC50 of this effect is 1.99 μg/mL.
Endotoxin Concentration<0.1 EU/μg
Expression SystemHEK293
SpeciesHuman
Amino Acids22-441 aa
SequenceSPSSLQGPELHGWRPPVDCVRANELCAAESNCSSRYRTLRQCLAGRDRNTMLANKECQAALEVLQESPLYDCRCKRGMKKELQCLQIYWSIHLGLTEGEEFYEASPYEPVTSRLSDIFRLASIFSGTGADPVVSAKSNHCLDAAKACNLNDNCKKLRSSYISICNREISPTERCNRRKCHKALRQFFDRVPSEYTYRMLFCSCQDQACAERRRQTILPSCSYEDKEKPNCLDLRGVCRTDHLCRSRLADFHANCR
Protein TagC-His
Accession #O00451-1
Predicted molecular weight47 kDa
SDS-PAGE75.0 kDa, under reducing conditions; 70.0 kDa, under non-reducing conditions.

Images

Recombinant Human GFR alpha-2/GFRA2 Protein (rp146403) - Protein Bioactivity
Immobilized Recombinant Human Neurturin Protein at 5.0 μg/mL can bind Recombinant Human GFR alpha-2/GFRA2 Protein (rp146403), the EC₅₀ of this effect is 1.99 μg/mL.

Recombinant Human GFR alpha-2/GFRA2 Protein (rp146403) - SDS-PAGE
3 μg/lane of Recombinant Human GFR alpha-2/GFRA2 Protein was resolved with SDS-PAGE under reducing (R) and non-reducing (N) conditions and visualized by Coomassie® Blue staining, showing the band at 75.0 kDa under reducing conditions and 70.0 kDa under non-reducing conditions.

Product Specifications

FormLyophilized
ReconstitutionReconstitute in sterile water to a concentration of 0.1-0.5 mg/ml.
Storage TempStore at -20°C,Avoid repeated freezing and thawing
Shipped InIce chest + Ice pads
Stability And StorageStore at -20~-80℃ for more than 1 year. Upon delivery aliquot. Avoid freeze/thaw cycle.

Certificates

Certificate of Analysis(COA)

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3 results found

Lot NumberCertificate TypeDateItem
ZJ24F0607373Certificate of AnalysisJun 28, 2024 rp146403
ZJ24F0607374Certificate of AnalysisJun 28, 2024 rp146403
ZJ24F0607375Certificate of AnalysisJun 28, 2024 rp146403

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