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Recombinant Human HGF GMP Protein

  • ActiBioPure™
  • Animal Free
  • Bioactive
  • Carrier Free
  • GMP
  • High Performance
  • ≥95%(SDS-PAGE&SEC-HPLC)
Features and benefits
  • Expression System: HEK293
  • Bioactivity: Measured by its ability to induce IL-11 secretion by Saos‑2 human osteosarcoma cells. The ED50 for this effect is equal or less than 4.00 ng/mL. The specific activity of recombinant human HGF is >1.0 x 10^6 IU/mg, which is calibrated against the human HGF
  • Endotoxin Concentration: < 0.1 EU/μg
Item Number
rp168049-GMP
Grouped product items
SKUSizeAvailabilityPrice Qty
rp168049-GMP-25μg
25μg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$1,569.90

GMP, ≥95% (SDS-PAGE&SEC-HPLC), Active, HEK293, C-His tag, 32-728 aa (D384N, D416N, L622S, H645R, V678I)

View related series
Accession#:P14210 Gene ID:3082 HGF

Basic Description

Product NameRecombinant Human HGF GMP Protein
GradeActiBioPure™, Animal Free, Bioactive, Carrier Free, GMP, High Performance
Specifications & PurityAnimal Free, Carrier Free, GMP, ActiBioPure™, Bioactive, High performance, ≥95%(SDS-PAGE&SEC-HPLC)
Biochemical and Physiological MechanismsPotent mitogen for mature parenchymal hepatocyte cells, seems to be a hepatotrophic factor, and acts as a growth factor for a broad spectrum of tissues and cell types. Activating ligand for the receptor tyrosine kinase MET by binding to it and promoting i
BioactivityMeasured by its ability to induce IL-11 secretion by Saos‑2 human osteosarcoma cells. The ED50 for this effect is equal or less than 4.00 ng/mL. The specific activity of recombinant human HGF is >1.0 x 10^6 IU/mg, which is calibrated against the human HGF
Endotoxin Concentration< 0.1 EU/μg
Expression SystemHEK293
Amino Acids32-728 aa (D384N, D416N, L622S, H645R, V678I)
SequenceQRKRRNTIHEFKKSAKTTLIKIDPALKIKTKKVNTADQCANRCTRNKGLPFTCKAFVFDKARKQCLWFPFNSMSSGVKKEFGHEFDLYENKDYIRNCIIGKGRSYKGTVSITKSGIKCQPWSSMIPHEHSFLPSSYRGKDLQENYCRNPRGEEGGPWCFTSNPEVRYEVCDIPQCSEVECMTCNGESYRGLMDHTESGKICQRWDHQTPHRHKFLPERYPDKGFDDNYCRNPDGQPRPWCYTLDPHTRWEYCAIK
N-terminal SequenceGln32-Arg-Lys-Arg-Arg-Asn-Thr-Ile-His-Glu (α-chain) Val495-Val-Asn-Gly-Ile-Pro-Thr-Arg-Thr-Asn (β-chain)
Predicted molecular weightα chain: 53.7 kDa, β chain: 26 kDa
SDS-PAGE71-85 kDa, non-reducing conditions. 56-65 kDa and 30-40 kDa, reducing conditions.

Product Specifications

ReconstitutionReconstitute at 100 μg/mL in PBS.
Storage TempStore at -20°C,Avoid repeated freezing and thawing
Shipped InIce chest + Ice pads
Stability And StorageA minimum of 12 months when stored at ≤ -20 ℃ as supplied. 1 month, 2 to 8 ℃ under sterile conditions after reconstitution. 3 months, ≤ -20 ℃ under sterile conditions after reconstitution. Upon delivery aliquot. Avoid freeze/thaw cycle.

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Solution Calculators