Recombinant Human IGFBP3 Protein, ≥95% (SDS-PAGE), high purity

Features and benefits
  • Expression System: HEK293
  • Accession #: P17936
  • Protein Tag: C-His
  • Bioactivity: Immobilized Human IGFBP3 Protein (rp147276) at 1.0 μg/mL can bind IGF-1 with a linear range of 0.7 - 50.0 ng/mL. The EC50 for this effect is 73.39 ng/mL.
  • Endotoxin Concentration: <0.1 EU/μg
Item Number
rp147276
Grouped product items
SKUSizeAvailabilityPrice Qty
rp147276-10μg
10μg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$99.90
rp147276-50μg
50μg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$279.90
rp147276-100μg
100μg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$529.90
rp147276-1mg
1mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$2,599.90

Animal Free, ≥95% (SDS-PAGE), Active, HEK293, C-His tag, 28-291 aa

Basic Description

Product NameRecombinant Human IGFBP3 Protein, ≥95% (SDS-PAGE), high purity
Synonymsacid stable subunit of the 140 K IGF complex | binding protein 29 | binding protein 53 | growth hormone-dependent binding protein | IBP-3 | IBP3BP-53 | IGF-binding protein 3 | IGFBP3 | IGFBP-3 | insulin-like growth factor binding protein 3 | insulin-like
GradeActiBioPure™, Animal Free, Azide Free, Bioactive, Carrier Free
Product Description

Purity
≥95% (SDS-PAGE)
Endotoxin level
<0.1 EU/μg
Function
IGF-binding proteins prolong the half-life of the IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs on cell culture. They alter the interaction of IGFs with their cell surface receptors.

Specifications & PurityActiBioPure™, Bioactive, Animal Free, Carrier Free, Azide Free, ≥95%(SDS-PAGE)
Purity≥95% (SDS-PAGE)
BioactivityImmobilized Human IGFBP3 Protein (rp147276) at 1.0 μg/mL can bind IGF-1 with a linear range of 0.7 - 50.0 ng/mL. The EC50 for this effect is 73.39 ng/mL.
Endotoxin Concentration<0.1 EU/μg
Expression SystemHEK293
SpeciesHuman
Amino Acids28-291 aa
SequenceGASSAGLGPVVRCEPCDARALAQCAPPPAVCAELVREPGCGCCLTCALSEGQPCGIYTERCGSGLRCQPSPDEARPLQALLDGRGLCVNASAVSRLRAYLLPAPPAPGNASESEEDRSAGSVESPSVSSTHRVSDPKFHPLHSKIIIIKKGHAKDSQRYKVDYESQSTDTQNFSSESKRETEYGPCRREMEDTLNHLKFLNVLSPRGVHIPNCDKKGFYKKKQCRPSKGRKRGFCWCVDKYGQPLPGYTTKGKED
Protein TagC-His
ConjugationUnconjugated
Accession #P17936
Predicted molecular weight29.7 kDa
SDS-PAGE40.0 - 50.0 kDa, under reducing conditions; 40.0 - 50.0 kDa, under non-reducing conditions.

Images

Recombinant Human IGFBP3 Protein (rp147276) - Protein Bioactivity
Immobilized Human IGFBP3 Protein (rp147276) at 1.0 μg/mL can bind IGF-1 with a linear range of 0.7 - 50.0 ng/mL. The EC₅₀ for this effect is 73.39 ng/mL.

Recombinant Human IGFBP3 Protein (rp147276) - SDS-PAGE
3 μg/lane of Recombinant Human IGFBP3 Protein was resolved with SDS-PAGE under reducing (R) and non-reducing (N) conditions and visualized by Coomassie® Blue staining, showing the band at 40.0 - 50.0 kDa.

Product Specifications

FormLyophilized
ReconstitutionReconstitute in sterile water to a concentration of 0.1-0.5 mg/ml.
Storage TempStore at -20°C,Avoid repeated freezing and thawing
Shipped InIce chest + Ice pads
Stability And StorageStore at -20~-80℃ for more than 1 year. Upon delivery aliquot. Avoid freeze/thaw cycle.

Certificates

Certificate of Analysis(COA)

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3 results found

Lot NumberCertificate TypeDateItem
ZJ24F0607348Certificate of AnalysisJun 28, 2024 rp147276
ZJ24F0607347Certificate of AnalysisJun 28, 2024 rp147276
ZJ24F0607346Certificate of AnalysisJun 28, 2024 rp147276

Related Documents

References

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